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Q8X6R3 (FUCK_ECO57) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
L-fuculokinase

EC=2.7.1.51
Alternative name(s):
L-fuculose kinase
Gene names
Name:fucK
Ordered Locus Names:Z4120, ECs3663
OrganismEscherichia coli O157:H7 [Complete proteome] [HAMAP]
Taxonomic identifier83334 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length482 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of L-fuculose By similarity. HAMAP-Rule MF_00986

Catalytic activity

ATP + L-fuculose = ADP + L-fuculose 1-phosphate. HAMAP-Rule MF_00986

Cofactor

Divalent metal cation By similarity. HAMAP-Rule MF_00986

Pathway

Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 2/3. HAMAP-Rule MF_00986

Sequence similarities

Belongs to the FGGY kinase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Fucose metabolism
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processfucose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

L-fuculokinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 482482L-fuculokinase HAMAP-Rule MF_00986
PRO_0000059424

Sequences

Sequence LengthMass (Da)Tools
Q8X6R3 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 42C7D3BC97D7D4C9

FASTA48253,234
        10         20         30         40         50         60 
MLSGYIAGAI MKQEVILVLD CGATNVRAIA VNRQGKIVAR ASTPNASDIA MENNTWHQWS 

        70         80         90        100        110        120 
LDAILQRFAD CCRQINSELT ECHIRGIAVT TFGVDGALVD KQGNLLYPII SWKCPRTAAV 

       130        140        150        160        170        180 
MDNIERLISA QRLQAISGVG AFSFNTLYKL VWLKENHPQL LERAHAWLFI SSLINHRLTG 

       190        200        210        220        230        240 
EFTTDITMAG TSQMLDIQQR DFSPQILQAT GIPRRLFPRL VEAGEQIGTL QNSAAAMLGL 

       250        260        270        280        290        300 
PVGIPVISAG HDTQFALFGA GAEQNEPVLS SGTWEILMVR SAQVDTSLLS QYAGSTCELD 

       310        320        330        340        350        360 
SQAGLYNPGM QWLASGVLEW VRKLFWTAET PWQMLIEEAR LIAPGADGVK MQCDLLSCQN 

       370        380        390        400        410        420 
AGWQGVTLNT TRGHFYRAAL EGLTAQLQRN LQMLEKIGHF KASELLLVGG GSRNTLWNQI 

       430        440        450        460        470        480 
KANMLDIPLK VLDDAETTVA GAALFGWYGV GEFNSPEEAR AQIHYQFRYF YPQTEPEFIE 


EV 

« Hide

References

[1]"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7."
Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W. expand/collapse author list , Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R.
Nature 409:529-533(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
[2]"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T. expand/collapse author list , Kuhara S., Shiba T., Hattori M., Shinagawa H.
DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005174 Genomic DNA. Translation: AAG57917.1.
BA000007 Genomic DNA. Translation: BAB37086.1.
PIRA85932.
G91086.
RefSeqNP_289358.1. NC_002655.2.
NP_311690.1. NC_002695.1.

3D structure databases

ProteinModelPortalQ8X6R3.
SMRQ8X6R3. Positions 11-481.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING155864.Z4120.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG57917; AAG57917; Z4120.
BAB37086; BAB37086; BAB37086.
GeneID916532.
958268.
KEGGece:Z4120.
ecs:ECs3663.
PATRIC18356805. VBIEscCol44059_3585.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1070.
HOGENOMHOG000124178.
KOK00879.
OMANIENDDW.
OrthoDBEOG6X9MHN.

Enzyme and pathway databases

BioCycECOL386585:GJFA-3627-MONOMER.
ECOO157:FUCK-MONOMER.
UniPathwayUPA00563; UER00625.

Family and domain databases

HAMAPMF_00986. Fuculokinase.
InterProIPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR013450. Fuculokinase.
[Graphical view]
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02628. fuculo_kin_coli. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFUCK_ECO57
AccessionPrimary (citable) accession number: Q8X6R3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways