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Protein

Superoxide dismutase [Cu-Zn]

Gene

Z3312

Organism
Escherichia coli O157:H7
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Z3312Imported
OrganismiEscherichia coli O157:H7Imported
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiQ8X6B6.

Structurei

3D structure databases

ProteinModelPortaliQ8X6B6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini189 – 327Sod_CuInterPro annotationAdd BLAST139

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108Z7T. Bacteria.
COG2032. LUCA.
HOGENOMiHOG000263449.
KOiK04565.

Family and domain databases

CDDicd00305. Cu-Zn_Superoxide_Dismutase. 1 hit.
Gene3Di2.60.40.200. 1 hit.
InterProiView protein in InterPro
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
PfamiView protein in Pfam
PF00080. Sod_Cu. 1 hit.
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiView protein in PROSITE
PS00332. SOD_CU_ZN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8X6B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFADVMVRVT GFAFVTSTPS PVSAPEDSKP SGGVCSCSPA RQTAVTPCIT
60 70 80 90 100
GLPSVSVSGV LFTRILCSPF TGPSIGPSPI ASITLIICVD LRLSFASRGV
110 120 130 140 150
CALPPPLPIM FLSIGIINRS DRILHSYCAI SSERCLLPCN QQAQSVNGIN
160 170 180 190 200
EGFMKCKIIA AIAMLTAASC GYAAEQEVPM NLVSADGKEV SIGKITIQET
210 220 230 240 250
PYGLLFTPAL HSLSEGIHGF HVHEKGNCAP ALKDGKPVAA LSAGGHFDPK
260 270 280 290 300
NTGKHLGPWS PDGHLGDLPA LFVTHDGKAN YPVLAPRLNS LKEIKGRSLM
310 320
LHAGGDNHHD HPEPLGGGGA RMACGIIQ
Length:328
Mass (Da):34,218
Last modified:March 1, 2002 - v1
Checksum:iE9DE6E85C988E5A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG57201.1.
PIRiE85842.
E90877.

Genome annotation databases

EnsemblBacteriaiAAG57201; AAG57201; Z3312.
KEGGiece:Z3312.

Similar proteinsi

Entry informationi

Entry nameiQ8X6B6_ECO57
AccessioniPrimary (citable) accession number: Q8X6B6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: September 27, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported