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Reviewed, UniProtKB/Swiss-Prot Q8X5J9 (MHPF_ECO57)

Last modified November 25, 2008. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Acetaldehyde dehydrogenase
    EC=1.2.1.10
Alternative name(s):
    Acetaldehyde dehydrogenase [acetylating]
Gene names
Name: mhpF
Ordered Locus Names: Z0450, ECs0406
OrganismEscherichia coli O157:H7 [Complete proteome] [HAMAP]
Taxonomic identifier83334 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the terminal reaction in meta-cleavage pathways, that is, the transformation of acetaldehyde into acetyl coenzyme A By similarity.

Catalytic activity

Acetaldehyde + CoA + NAD(+) = acetyl-CoA + NADH.

Pathway

Aromatic compound metabolism; 3-phenylpropionic acid degradation.

Subunit structure

Interacts with mhpE By similarity.

Sequence similarities

Belongs to the acetaldehyde dehydrogenase family. MhpF subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 316316Acetaldehyde dehydrogenase
PRO_0000337980

Sequences

Sequence LengthMass (Da)Tools
Q8X5J9-1 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 6709FAC7425DFFB5

FASTA31633,587
        10         20         30         40         50         60 
MSKRKVAIIG SGNIGTDLMI KILRHDQHLE MAVMVGIDPQ SDGLARARRM GVATTHEGVI 

        70         80         90        100        110        120 
GLMNMPEFAD IDIVFDATSA GAHVKNDAAL REAKPDIRLI DLTPAAIGPY CVPVVNLEEN 

       130        140        150        160        170        180 
VDQLNVNMVT CGGQATIPMV AAVSRVVRVH YAEIIASIAS KSAGPGTRAN IDEFTETTSR 

       190        200        210        220        230        240 
AIEVVGGAAK GKAIIVLNPA EPPLMMRDTV YVLSDEASQD DIEASINEMA EAVQAYVPGY 

       250        260        270        280        290        300 
RLKQRVQFEV IPQDKPVNLP GVGQFSGLKT AVWLEVEGAA HYLPAYAGNL DIMTSSALAT 

       310 
AEKMAQSLAR KAGEAA 

« Hide

References

Cross-references

Sequence databases

AE005174 Genomic DNA. Translation: AAG54702.1.
BA000007 Genomic DNA. Translation: BAB33829.1.
PIRB85530.
F90679.
RefSeqNP_286094.1.
NP_308433.1.

3D structure databases

SMRQ8X5J9. Positions 3-308.
ModBaseSearch...

Genome annotation databases

GeneID914508.
957291.
GenomeReviewsGene locus ECs0406 in contig BA000007_GR.
Gene locus Z0450 in contig AE005174_GR.
KEGGece:Z0450.
ecs:ECs0406.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ8X5J9.

Enzyme and pathway databases

BioCycECOL83334:ECS0406-MON.

Family and domain databases

HAMAPMF_01657.
[Tree]
InterProIPR003361. Acetylald_dehydrogenase.
IPR015426. Acetylald_DHase_C.
IPR000534. Semialdehyde_DHase_NAD-bd.
[Graphical view]
PANTHERPTHR21123. Acetylald_dh. 1 hit.
PfamPF09290. AcetDehyd-dimer. 1 hit.
PF01118. Semialdhyde_dh. 1 hit.
[Graphical view]
PIRSFPIRSF015689. Actaldh_dh_actl. 1 hit.
TIGRFAMsTIGR03215. ac_ald_DH_ac. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMHPF_ECO57
AccessionPrimary (citable) accession number: Q8X5J9
Secondary accession number(s): Q7AH50
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 1, 2002
Last modified: November 25, 2008
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents