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Q8X178

- PP2A2_BLUGH

UniProt

Q8X178 - PP2A2_BLUGH

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Protein
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit
Gene
PP2A-2
Organism
Blumeria graminis f. sp. hordei (Barley powdery mildew) (Oidium monilioides f. sp. hordei)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi76 – 761Manganese 1 By similarity
Metal bindingi78 – 781Manganese 1 By similarity
Metal bindingi104 – 1041Manganese 1 By similarity
Metal bindingi104 – 1041Manganese 2 By similarity
Metal bindingi136 – 1361Manganese 2 By similarity
Active sitei137 – 1371Proton donor By similarity
Metal bindingi186 – 1861Manganese 2 By similarity
Metal bindingi260 – 2601Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit (EC:3.1.3.16)
Gene namesi
Name:PP2A-2
OrganismiBlumeria graminis f. sp. hordei (Barley powdery mildew) (Oidium monilioides f. sp. hordei)
Taxonomic identifieri62688 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaLeotiomycetesErysiphalesErysiphaceaeBlumeria

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 328328Serine/threonine-protein phosphatase PP2A-2 catalytic subunit
PRO_0000058869Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei328 – 3281Leucine methyl ester By similarity

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiQ8X178.

Structurei

3D structure databases

ProteinModelPortaliQ8X178.
SMRiQ8X178. Positions 29-328.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8X178-1 [UniParc]FASTAAdd to Basket

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MDTKMEDVGK TPEPIRFQTT TEPASISTLD GWIENLMACK QLPEVDVLRL    50
CEKAREVLHS ESNVQPVKCP VTVCGDIHGQ FHDLMELFRI GGPNPDTNYL 100
FMGDYVDRGY YSVETVTLLV ALKIRYPQRI TILRGNHESR QITQVYGFYD 150
ECLRKYGNAN VWKYFTNLFD FLPLTALIEN QIFCLHGGLS PSIDTLDNIK 200
SLDRIQEVPH EGPMCDLLWS DPDDRCGWGI SPRGAGYTFG QDISEAFNHN 250
NGLTLVARAH QLVMEGYNWS QDRNVVTIFS APNYCYRCGN QAAIMEIDEH 300
LKYTFLQFDP CPRAGEPMVT RRTPDYFL 328
Length:328
Mass (Da):37,486
Last modified:March 1, 2002 - v1
Checksum:iC5339E5D238618AE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF462042 Genomic DNA. Translation: AAL69898.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF462042 Genomic DNA. Translation: AAL69898.1 .

3D structure databases

ProteinModelPortali Q8X178.
SMRi Q8X178. Positions 29-328.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q8X178.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Zhang Z., Scott P., Gurr S.J.
    Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiPP2A2_BLUGH
AccessioniPrimary (citable) accession number: Q8X178
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: March 1, 2002
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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