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Q8X169 (GLNA_AMAMU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

Short name=GS
EC=6.3.1.2
Alternative name(s):
Glutamate--ammonia ligase
Gene names
Name:GLN1
OrganismAmanita muscaria (Fly agaric)
Taxonomic identifier41956 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesAmanitaceaeAmanita

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homooctamer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the glutamine synthetase family.

Sequence caution

The sequence CAD22045.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 354354Glutamine synthetase
PRO_0000153150

Sequences

Sequence LengthMass (Da)Tools
Q8X169 [UniParc].

Last modified April 13, 2004. Version 2.
Checksum: 10C9AC87BCF5257E

FASTA35439,337
        10         20         30         40         50         60 
MANQYHNDLL APYLALDQGG KFHAEYVWID GDGGLRSKTT TVDQKVTDIS QLRVWDFDGS 

        70         80         90        100        110        120 
STNQAPSGNS DVYLRPSAIF KDPFRGGENI LVLSETYNND GTPNRTNHRH HTAKVMELAK 

       130        140        150        160        170        180 
DEIPWFGIEQ EYTLFDADGS PYGWPKGGFP GPQGPYYCGA GTGKVFARDL IEAHYRACLY 

       190        200        210        220        230        240 
AGVNISGINA EVMPSQWEFQ VGPCEGISMG DHLWMARYLL IRVAEQWGVK VSFHPKPLQG 

       250        260        270        280        290        300 
DWNGAGAHTN YSTLAMREPG GMKYIEAAIE KLAKRHDEHI AVYGEDNEMR LTGRHETGHI 

       310        320        330        340        350 
GTFSSGVANR GASIRVPRHV ANKGYGYLED RRPASNIDPY RVTGIIIETT ILDK 

« Hide

References

[1]"Glutamine synthetase in Amanita muscaria."
Nehls U., Kleber R., Hampp R.
Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ428992 mRNA. Translation: CAD22045.1. Different initiation.

3D structure databases

ProteinModelPortalQ8X169.
SMRQ8X169. Positions 17-354.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ8X169.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
PROSITEPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA_AMAMU
AccessionPrimary (citable) accession number: Q8X169
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: April 13, 2004
Last modified: October 16, 2013
This is version 42 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families