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Q8X169

- GLNA_AMAMU

UniProt

Q8X169 - GLNA_AMAMU

Protein

Glutamine synthetase

Gene

GLN1

Organism
Amanita muscaria (Fly agaric)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 2 (13 Apr 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamate-ammonia ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glutamine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine synthetase (EC:6.3.1.2)
    Short name:
    GS
    Alternative name(s):
    Glutamate--ammonia ligase
    Gene namesi
    Name:GLN1
    OrganismiAmanita muscaria (Fly agaric)
    Taxonomic identifieri41956 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesAmanitaceaeAmanita

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 354354Glutamine synthetasePRO_0000153150Add
    BLAST

    Proteomic databases

    PRIDEiQ8X169.

    Interactioni

    Subunit structurei

    Homooctamer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ8X169.
    SMRiQ8X169. Positions 17-354.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutamine synthetase family.Curated

    Family and domain databases

    Gene3Di3.30.590.10. 1 hit.
    InterProiIPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view]
    PfamiPF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54368. SSF54368. 1 hit.
    PROSITEiPS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8X169-1 [UniParc]FASTAAdd to Basket

    « Hide

    MANQYHNDLL APYLALDQGG KFHAEYVWID GDGGLRSKTT TVDQKVTDIS    50
    QLRVWDFDGS STNQAPSGNS DVYLRPSAIF KDPFRGGENI LVLSETYNND 100
    GTPNRTNHRH HTAKVMELAK DEIPWFGIEQ EYTLFDADGS PYGWPKGGFP 150
    GPQGPYYCGA GTGKVFARDL IEAHYRACLY AGVNISGINA EVMPSQWEFQ 200
    VGPCEGISMG DHLWMARYLL IRVAEQWGVK VSFHPKPLQG DWNGAGAHTN 250
    YSTLAMREPG GMKYIEAAIE KLAKRHDEHI AVYGEDNEMR LTGRHETGHI 300
    GTFSSGVANR GASIRVPRHV ANKGYGYLED RRPASNIDPY RVTGIIIETT 350
    ILDK 354
    Length:354
    Mass (Da):39,337
    Last modified:April 13, 2004 - v2
    Checksum:i10C9AC87BCF5257E
    GO

    Sequence cautioni

    The sequence CAD22045.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ428992 mRNA. Translation: CAD22045.1. Different initiation.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ428992 mRNA. Translation: CAD22045.1 . Different initiation.

    3D structure databases

    ProteinModelPortali Q8X169.
    SMRi Q8X169. Positions 17-354.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q8X169.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.30.590.10. 1 hit.
    InterProi IPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view ]
    Pfami PF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54368. SSF54368. 1 hit.
    PROSITEi PS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Glutamine synthetase in Amanita muscaria."
      Nehls U., Kleber R., Hampp R.
      Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiGLNA_AMAMU
    AccessioniPrimary (citable) accession number: Q8X169
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 13, 2004
    Last sequence update: April 13, 2004
    Last modified: October 1, 2014
    This is version 43 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3