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Q8X123 (Q8X123_9AGAR) Unreviewed, UniProtKB/TrEMBL

Last modified July 27, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Agglutinin EMBL AAL47680.1
OrganismMarasmius oreades EMBL AAL47680.1
Taxonomic identifier181124 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Homobasidiomycetes › Agaricomycetidae › Agaricales › Marasmiaceae › Marasmius

Protein attributes

Sequence length293 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   LigandCalcium PDB 3EF2
Metal-binding PDB 3EF2
   Technical term3D-structure PDB 2IHO PDB 3EF2
Gene Ontology (GO)
   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region20 – 234Galactose binding PDB 2IHO PDB 3EF2
Region35 – 384Galactose binding PDB 2IHO PDB 3EF2
Region43 – 453Galactose binding PDB 2IHO PDB 3EF2
Region72 – 754Galactose binding PDB 2IHO PDB 3EF2
Region87 – 882Galactose binding PDB 2IHO
Region95 – 973Galactose binding PDB 2IHO PDB 3EF2

Sites

Metal binding1821Calcium 1; via carbonyl oxygen PDB 3EF2
Metal binding1831Calcium 1 PDB 3EF2
Metal binding1831Calcium 2 PDB 3EF2
Metal binding2111Calcium 2; via carbonyl oxygen PDB 3EF2
Metal binding2141Calcium 1 PDB 3EF2
Metal binding2141Calcium 2 PDB 3EF2
Metal binding2161Calcium 1 PDB 3EF2
Metal binding2161Calcium 2 PDB 3EF2
Metal binding2171Calcium 2 PDB 3EF2
Binding site231N-acetyl-D-glucosamine PDB 2IHO
Binding site751N-acetyl-D-glucosamine PDB 2IHO

Sequences

Sequence LengthMass (Da)Tools
Q8X123 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: AC67E1420EB5700B

FASTA29332,301
        10         20         30         40         50         60 
MSLRRGIYHI ENAGVPSAID LKDGSSSDGT PIVGWQFTPD TINWHQLWLA EPIPNVADTF 

        70         80         90        100        110        120 
TLCNLFSGTY MDLYNGSSEA GTAVNGWQGT AFTTNPHQLW TIKKSSDGTS YKIQNYGSKT 

       130        140        150        160        170        180 
FVDLVNGDSS DGAKIAGWTG TWDEGNPHQK WYFNRMSVSS AEAQAAIARN PHIHGTYRGY 

       190        200        210        220        230        240 
ILDGEYLVLP NATFTQIWKD SGLPGSKWRE QIYDCDDFAI AMKAAVGKWG ADSWKANGFA 

       250        260        270        280        290 
IFCGVMLGVN KAGDAAHAYN FTLTKDHADI VFFEPQNGGY LNDIGYDSYM AFY

« Hide

References

[1]"Cloning, Expression, and Characterization of MOA the Gal-alpha1,3-gal High Affinity Lectin from the Mushroom Marasmius oreades."
Kruger R.P., Winter H.C., Simonson-Leff N., Dixon J.E., Goldstein I.J.
Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Crystal structure of the Marasmius oreades mushroom lectin in complex with a xenotransplantation epitope."
Grahn E., Askarieh G., Holmner A., Tateno H., Winter H.C., Goldstein I.J., Krengel U.
J. Mol. Biol. 369:710-721(2007) [PubMed: 17442345] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.41 ANGSTROMS) IN COMPLEX WITH GALACTOSE AND N-ACETYL-D-GLUCOSAMINE.
[3]"Structural characterization of a lectin from the mushroom Marasmius oreades in complex with the blood group B trisaccharide and calcium."
Grahn E.M., Winter H.C., Tateno H., Goldstein I.J., Krengel U.
J. Mol. Biol. 390:457-466(2009) [PubMed: 19426740] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH CALCIUM AND GALACTOSE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY066013 mRNA. Translation: AAL47680.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2IHOX-ray2.41A1-293[»]
3EF2X-ray1.80A/B/C/D1-293[»]
ProteinModelPortalQ8X123.
SMRQ8X123. Positions 2-293.
ModBaseSearch...

Protein family/group databases

CAZyCBM13. Carbohydrate-Binding Module Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR008997. Ricin_B-rel_lectin.
IPR000772. Ricin_B_lectin.
[Graphical view]
SUPFAMSSF50370. RicinB_like. 1 hit.
PROSITEPS50231. RICIN_B_LECTIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8X123_9AGAR
AccessionPrimary (citable) accession number: Q8X123
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: July 27, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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