##gff-version 3
Q8WZ75	UniProtKB	Signal peptide	1	27	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8WZ75	UniProtKB	Chain	28	1007	.	.	.	ID=PRO_0000031040;Note=Roundabout homolog 4	
Q8WZ75	UniProtKB	Domain	32	131	.	.	.	Note=Ig-like C2-type 1	
Q8WZ75	UniProtKB	Domain	137	224	.	.	.	Note=Ig-like C2-type 2	
Q8WZ75	UniProtKB	Domain	248	345	.	.	.	Note=Fibronectin type-III 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00316	
Q8WZ75	UniProtKB	Domain	347	442	.	.	.	Note=Fibronectin type-III 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00316	
Q8WZ75	UniProtKB	Region	531	551	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8WZ75	UniProtKB	Region	713	793	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8WZ75	UniProtKB	Region	806	826	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8WZ75	UniProtKB	Region	971	1007	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8WZ75	UniProtKB	Compositional bias	531	548	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8WZ75	UniProtKB	Compositional bias	724	739	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8WZ75	UniProtKB	Compositional bias	752	766	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8WZ75	UniProtKB	Compositional bias	767	790	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8WZ75	UniProtKB	Modified residue	805	805	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:24275569;Dbxref=PMID:24275569	
Q8WZ75	UniProtKB	Modified residue	938	938	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8C310	
Q8WZ75	UniProtKB	Glycosylation	246	246	.	.	.	Note=N-linked (GlcNAc...) (complex) asparagine;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16335952,ECO:0000269|PubMed:19139490;Dbxref=PMID:16335952,PMID:19139490	
Q8WZ75	UniProtKB	Glycosylation	360	360	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8WZ75	UniProtKB	Glycosylation	389	389	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8WZ75	UniProtKB	Glycosylation	396	396	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8WZ75	UniProtKB	Glycosylation	680	680	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8WZ75	UniProtKB	Disulfide bond	53	114	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00114	
Q8WZ75	UniProtKB	Disulfide bond	158	207	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00114	
Q8WZ75	UniProtKB	Alternative sequence	24	133	.	.	.	ID=VSP_010654;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q8WZ75	UniProtKB	Alternative sequence	813	1007	.	.	.	ID=VSP_010657;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q8WZ75	UniProtKB	Alternative sequence	932	933	.	.	.	ID=VSP_010658;Note=In isoform 2. DA->GM;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q8WZ75	UniProtKB	Alternative sequence	934	1007	.	.	.	ID=VSP_010659;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q8WZ75	UniProtKB	Natural variant	54	54	.	.	.	ID=VAR_062146;Note=Q->R;Dbxref=dbSNP:rs59648931	
Q8WZ75	UniProtKB	Natural variant	64	64	.	.	.	ID=VAR_083093;Note=In AOVD3%3B loss of endothelial barrier function in a dextran permeability assay. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs201393279,PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	95	95	.	.	.	ID=VAR_083094;Note=In AOVD3%3B uncertain significance. A->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs138370967,PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	232	232	.	.	.	ID=VAR_083095;Note=In AOVD3%3B uncertain significance. T->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs150700978,PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	247	247	.	.	.	ID=VAR_083096;Note=In AOVD3%3B uncertain significance. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs779392207,PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	280	280	.	.	.	ID=VAR_083097;Note=In AOVD3%3B uncertain significance. Y->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs755747435,PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	411	411	.	.	.	ID=VAR_083098;Note=In AOVD3%3B uncertain significance. H->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs1565326476,PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	510	510	.	.	.	ID=VAR_083099;Note=In AOVD3%3B uncertain significance. D->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs1565325937,PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	568	1007	.	.	.	ID=VAR_083100;Note=In AOVD3%3B uncertain significance. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	622	622	.	.	.	ID=VAR_083101;Note=In AOVD3%3B uncertain significance. D->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs138111911,PMID:30455415	
Q8WZ75	UniProtKB	Natural variant	669	669	.	.	.	ID=VAR_053644;Note=R->Q;Dbxref=dbSNP:rs4408324	
Q8WZ75	UniProtKB	Natural variant	749	749	.	.	.	ID=VAR_083102;Note=In AOVD3%3B uncertain significance%3B requires 2 nucleotide substitutions. A->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30455415;Dbxref=dbSNP:rs1565322176,PMID:30455415	
Q8WZ75	UniProtKB	Sequence conflict	175	175	.	.	.	Note=G->E;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8WZ75	UniProtKB	Sequence conflict	498	498	.	.	.	Note=H->L;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8WZ75	UniProtKB	Sequence conflict	652	652	.	.	.	Note=Q->P;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8WZ75	UniProtKB	Sequence conflict	662	662	.	.	.	Note=G->D;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8WZ75	UniProtKB	Sequence conflict	860	860	.	.	.	Note=P->L;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8WZ75	UniProtKB	Sequence conflict	864	864	.	.	.	Note=L->F;Ontology_term=ECO:0000305;evidence=ECO:0000305