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Q8WZ47 (Q8WZ47_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Sex-determining region Y protein PIRNR PIRNR037653
Gene names
Name:SRY EMBL CAD13147.1
OrganismHomo sapiens (Human) EMBL CAD13147.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length198 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transcriptional regulator that controls a genetic switch in male development By similarity. PIRNR PIRNR037653

Sequence similarities

Belongs to the SRY family. PIRNR PIRNR037653

Contains HMG box DNA-binding domain. SAAS SAAS017253

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue1981 EMBL CAD13147.1

Sequences

Sequence LengthMass (Da)Tools
Q8WZ47 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 7725A9452C308121

FASTA19823,032
        10         20         30         40         50         60 
MQSYASAMLS VFNSDDYSPA VQENIPALRR SSSFLCTESC NSKYQCETGE NSKGNVQDGV 

        70         80         90        100        110        120 
KRPMNAFIVW SRDQRRKMAL ENPRMRNSEI SKQLGYQWKM LTEAEKWPFF QEAQKLQAMH 

       130        140        150        160        170        180 
REKYPNYKYR PRRKAKMLPK NCSLLPADPA SVLCSEVQLD NRLYRDDCTK ATHSRMEHQL 

       190 
GHLPPINAAS SPQQRDRY 

« Hide

References

[1]"A point mutation R59G within the HMG-SRY box in a female 45,X/46,X,psu dic(Y)(pter=AEq11::q11=AEpter)."
Fernandez R., Marchal J.A., Sanchez A., Pasaro E.
Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ421270 Genomic DNA. Translation: CAD13147.1.
UniGeneHs.1992.

3D structure databases

ProteinModelPortalQ8WZ47.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-1208803.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG008712.

Family and domain databases

Gene3D1.10.30.10. 1 hit.
InterProIPR009071. HMG_box_dom.
IPR017253. TF_Sry.
[Graphical view]
PANTHERPTHR10270:SF48. PTHR10270:SF48. 1 hit.
PfamPF00505. HMG_box. 1 hit.
[Graphical view]
PIRSFPIRSF037653. SRY. 1 hit.
SMARTSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMSSF47095. SSF47095. 1 hit.
PROSITEPS50118. HMG_BOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8WZ47_HUMAN
AccessionPrimary (citable) accession number: Q8WZ47
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: February 19, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.