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Q8WXX7

- AUTS2_HUMAN

UniProt

Q8WXX7 - AUTS2_HUMAN

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Protein

Autism susceptibility gene 2 protein

Gene

AUTS2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Autism susceptibility gene 2 protein
Gene namesi
Name:AUTS2
Synonyms:KIAA0442
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:14262. AUTS2.

Pathology & Biotechi

Involvement in diseasei

Mental retardation, autosomal dominant 26 (MRD26) [MIM:615834]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Additional MRD26 features include autism, short stature, microcephaly, cerebral palsy, and facial dysmorphisms.1 Publication
Note: The disease is caused by mutations affecting the gene represented in this entry.

Keywords - Diseasei

Mental retardation

Organism-specific databases

MIMi615834. phenotype.
Orphaneti106. Autism.
352490. Autism spectrum disorder due to AUTS2 deficiency.
99860. Precursor B-cell acute lymphoblastic leukemia.
PharmGKBiPA134863175.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12591259Autism susceptibility gene 2 proteinPRO_0000064767Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1198 – 11981Phosphoserine1 Publication
Modified residuei1233 – 12331Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8WXX7.
PRIDEiQ8WXX7.

PTM databases

PhosphoSiteiQ8WXX7.

Expressioni

Tissue specificityi

Strongly expressed in brain, skeletal muscle and kidney. Also expressed in placenta, lung and leukocytes.2 Publications

Gene expression databases

BgeeiQ8WXX7.
CleanExiHS_AUTS2.
ExpressionAtlasiQ8WXX7. baseline and differential.
GenevestigatoriQ8WXX7.

Organism-specific databases

HPAiHPA000390.

Interactioni

Protein-protein interaction databases

BioGridi117516. 5 interactions.
IntActiQ8WXX7. 2 interactions.
STRINGi9606.ENSP00000344087.

Structurei

3D structure databases

ProteinModelPortaliQ8WXX7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi383 – 41028Ser-richAdd
BLAST
Compositional biasi525 – 54824His-richAdd
BLAST
Compositional biasi1122 – 118160His-richAdd
BLAST

Sequence similaritiesi

Belongs to the AUTS2 family.Curated

Phylogenomic databases

eggNOGiNOG41815.
GeneTreeiENSGT00390000001466.
HOGENOMiHOG000143450.
HOVERGENiHBG050644.
InParanoidiQ8WXX7.
OMAiYEADRSF.
OrthoDBiEOG7CG6ZH.
PhylomeDBiQ8WXX7.
TreeFamiTF331929.

Family and domain databases

InterProiIPR023246. AUTS2.
[Graphical view]
PRINTSiPR02044. FIBROSIN1LPF.

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1Curated (identifier: Q8WXX7-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDGPTRGHGL RKKRRSRSQR DRERRSRGGL GAGAAGGGGA GRTRALSLAS
60 70 80 90 100
SSGSDKEDNG KPPSSAPSRP RPPRRKRRES TSAEEDIIDG FAMTSFVTFE
110 120 130 140 150
ALEKDVALKP QERVEKRQTP LTKKKREALT NGLSFHSKKS RLSHPHHYSS
160 170 180 190 200
DRENDRNLCQ HLGKRKKMPK ALRQLKPGQN SCRDSDSESA SGESKGFHRS
210 220 230 240 250
SSRERLSDSS APSSLGTGYF CDSDSDQEEK ASDASSEKLF NTVIVNKDPE
260 270 280 290 300
LGVGTLPEHD SQDAGPIVPK ISGLERSQEK SQDCCKEPIF EPVVLKDPCP
310 320 330 340 350
QVAQPIPQPQ TEPQLRAPSP DPDLVQRTEA PPQPPPLSTQ PPQGPPEAQL
360 370 380 390 400
QPAPQPQVQR PPRPQSPTQL LHQNLPPVQA HPSAQSLSQP LSAYNSSSLS
410 420 430 440 450
LNSLSSSRSS TPAKTQPAPP HISHHPSASP FPLSLPNHSP LHSFTPTLQP
460 470 480 490 500
PAHSHHPNMF APPTALPPPP PLTSGSLQVA GHPAGSTYSE QDILRQELNT
510 520 530 540 550
RFLASQSADR GASLGPPPYL RTEFHQHQHQ HQHTHQHTHQ HTFTPFPHAI
560 570 580 590 600
PPTAIMPTPA PPMFDKYPTK VDPFYRHSLF HSYPPAVSGI PPMIPPTGPF
610 620 630 640 650
GSLQGAFQPK TSNPIDVAAR PGTVPHTLLQ KDPRLTDPFR PMLRKPGKWC
660 670 680 690 700
AMHVHIAWQI YHHQQKVKKQ MQSDPHKLDF GLKPEFLSRP PGPSLFGAIH
710 720 730 740 750
HPHDLARPST LFSAAGAAHP TGTPFGPPPH HSNFLNPAAH LEPFNRPSTF
760 770 780 790 800
TGLAAVGGNA FGGLGNPSVT PNSMFGHKDG PSVQNFSNPH EPWNRLHRTP
810 820 830 840 850
PSFPTPPPWL KPGELERSAS AAAHDRDRDV DKRDSSVSKD DKERESVEKR
860 870 880 890 900
HSSHPSPAPV LPVNALGHTR SSTEQIRAHL NTEAREKDKP KERERDHSES
910 920 930 940 950
RKDLAADEHK AKEGHLPEKD GHGHEGRAAG EEAKQLARVP SPYVRTPVVE
960 970 980 990 1000
SARPNSTSSR EAEPRKGEPA YENPKKSSEV KVKEERKEDH DLPPEAPQTH
1010 1020 1030 1040 1050
RASEPPPPNS SSSVHPGPLA SMPMTVGVTG IHPMNSISSL DRTRMMTPFM
1060 1070 1080 1090 1100
GISPLPGGER FPYPSFHWDP IRDPLRDPYR ELDIHRRDPL GRDFLLRNDP
1110 1120 1130 1140 1150
LHRLSTPRLY EADRSFRDRE PHDYSHHHHH HHHPLSVDPR REHERGGHLD
1160 1170 1180 1190 1200
ERERLHMLRE DYEHTRLHSV HPASLDGHLP HPSLITPGLP SMHYPRISPT
1210 1220 1230 1240 1250
AGNQNGLLNK TPPTAALSAP PPLISTLGGR PVSPRRTTPL SAEIRERPPS

HTLKDIEAR
Length:1,259
Mass (Da):138,982
Last modified:March 1, 2002 - v1
Checksum:iA64D17AFF816E591
GO
Isoform 2Curated (identifier: Q8WXX7-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     611-634: Missing.

Note: No experimental confirmation available.

Show »
Length:1,235
Mass (Da):136,416
Checksum:iC5875E61E209B949
GO
Isoform 3Curated (identifier: Q8WXX7-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     221-266: CDSDSDQEEK...PEHDSQDAGP → RSGKMCLGEE...FSLVKLLKGF
     267-1259: Missing.

Note: No experimental confirmation available.

Show »
Length:266
Mass (Da):29,323
Checksum:i5DE33CA2D1AD11A4
GO
Isoform 5Curated (identifier: Q8WXX7-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-555: Missing.
     611-634: Missing.

Show »
Length:680
Mass (Da):75,998
Checksum:i694A64D7257BBA46
GO

Sequence cautioni

The sequence BAA23714.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortenedCurated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti177 – 1771P → S in BAA23714. (PubMed:9455477)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti303 – 3031A → S.1 Publication
Corresponds to variant rs2293507 [ dbSNP | Ensembl ].
VAR_013864

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 555555Missing in isoform 5. 1 PublicationVSP_057063Add
BLAST
Alternative sequencei221 – 26646CDSDS…QDAGP → RSGKMCLGEEACLKSGNDMK RDVSNTSSWASNRESFFSLV KLLKGF in isoform 3. 1 PublicationVSP_043556Add
BLAST
Alternative sequencei267 – 1259993Missing in isoform 3. 1 PublicationVSP_043557Add
BLAST
Alternative sequencei611 – 63424Missing in isoform 2 and isoform 5. 3 PublicationsVSP_003792Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ670866 mRNA. Translation: AFY24235.1.
JQ670867 mRNA. Translation: AFY24236.1.
AF326917 mRNA. Translation: AAL37411.1.
AB007902 mRNA. Translation: BAA23714.2. Different initiation.
AC004773 Genomic DNA. No translation available.
AC004881 Genomic DNA. No translation available.
AC004927 Genomic DNA. No translation available.
AC006012 Genomic DNA. No translation available.
AC006317 Genomic DNA. No translation available.
AC006318 Genomic DNA. No translation available.
AC006319 Genomic DNA. No translation available.
AC006361 Genomic DNA. No translation available.
AC073148 Genomic DNA. No translation available.
AC073873 Genomic DNA. No translation available.
AC093487 Genomic DNA. No translation available.
AC093679 Genomic DNA. No translation available.
AC093685 Genomic DNA. No translation available.
CH236952 Genomic DNA. Translation: EAL23968.1.
BC011643 mRNA. Translation: AAH11643.1.
BC064693 mRNA. Translation: AAH64693.1.
CCDSiCCDS47601.1. [Q8WXX7-2]
CCDS47602.1. [Q8WXX7-3]
CCDS5539.1. [Q8WXX7-1]
PIRiT00065.
RefSeqiNP_001120703.1. NM_001127231.2. [Q8WXX7-2]
NP_001120704.1. NM_001127232.2. [Q8WXX7-3]
NP_056385.1. NM_015570.3. [Q8WXX7-1]
UniGeneiHs.21631.
Hs.712991.

Genome annotation databases

EnsembliENST00000342771; ENSP00000344087; ENSG00000158321. [Q8WXX7-1]
ENST00000403018; ENSP00000385572; ENSG00000158321. [Q8WXX7-3]
ENST00000406775; ENSP00000385263; ENSG00000158321. [Q8WXX7-2]
GeneIDi26053.
KEGGihsa:26053.
UCSCiuc003tvv.4. human. [Q8WXX7-3]
uc003tvw.4. human. [Q8WXX7-1]
uc003tvx.4. human. [Q8WXX7-2]

Polymorphism databases

DMDMi23396464.

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ670866 mRNA. Translation: AFY24235.1 .
JQ670867 mRNA. Translation: AFY24236.1 .
AF326917 mRNA. Translation: AAL37411.1 .
AB007902 mRNA. Translation: BAA23714.2 . Different initiation.
AC004773 Genomic DNA. No translation available.
AC004881 Genomic DNA. No translation available.
AC004927 Genomic DNA. No translation available.
AC006012 Genomic DNA. No translation available.
AC006317 Genomic DNA. No translation available.
AC006318 Genomic DNA. No translation available.
AC006319 Genomic DNA. No translation available.
AC006361 Genomic DNA. No translation available.
AC073148 Genomic DNA. No translation available.
AC073873 Genomic DNA. No translation available.
AC093487 Genomic DNA. No translation available.
AC093679 Genomic DNA. No translation available.
AC093685 Genomic DNA. No translation available.
CH236952 Genomic DNA. Translation: EAL23968.1 .
BC011643 mRNA. Translation: AAH11643.1 .
BC064693 mRNA. Translation: AAH64693.1 .
CCDSi CCDS47601.1. [Q8WXX7-2 ]
CCDS47602.1. [Q8WXX7-3 ]
CCDS5539.1. [Q8WXX7-1 ]
PIRi T00065.
RefSeqi NP_001120703.1. NM_001127231.2. [Q8WXX7-2 ]
NP_001120704.1. NM_001127232.2. [Q8WXX7-3 ]
NP_056385.1. NM_015570.3. [Q8WXX7-1 ]
UniGenei Hs.21631.
Hs.712991.

3D structure databases

ProteinModelPortali Q8WXX7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 117516. 5 interactions.
IntActi Q8WXX7. 2 interactions.
STRINGi 9606.ENSP00000344087.

PTM databases

PhosphoSitei Q8WXX7.

Polymorphism databases

DMDMi 23396464.

Proteomic databases

PaxDbi Q8WXX7.
PRIDEi Q8WXX7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000342771 ; ENSP00000344087 ; ENSG00000158321 . [Q8WXX7-1 ]
ENST00000403018 ; ENSP00000385572 ; ENSG00000158321 . [Q8WXX7-3 ]
ENST00000406775 ; ENSP00000385263 ; ENSG00000158321 . [Q8WXX7-2 ]
GeneIDi 26053.
KEGGi hsa:26053.
UCSCi uc003tvv.4. human. [Q8WXX7-3 ]
uc003tvw.4. human. [Q8WXX7-1 ]
uc003tvx.4. human. [Q8WXX7-2 ]

Organism-specific databases

CTDi 26053.
GeneCardsi GC07P069063.
HGNCi HGNC:14262. AUTS2.
HPAi HPA000390.
MIMi 607270. gene.
615834. phenotype.
neXtProti NX_Q8WXX7.
Orphaneti 106. Autism.
352490. Autism spectrum disorder due to AUTS2 deficiency.
99860. Precursor B-cell acute lymphoblastic leukemia.
PharmGKBi PA134863175.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG41815.
GeneTreei ENSGT00390000001466.
HOGENOMi HOG000143450.
HOVERGENi HBG050644.
InParanoidi Q8WXX7.
OMAi YEADRSF.
OrthoDBi EOG7CG6ZH.
PhylomeDBi Q8WXX7.
TreeFami TF331929.

Miscellaneous databases

ChiTaRSi AUTS2. human.
GenomeRNAii 26053.
NextBioi 47920.
PROi Q8WXX7.
SOURCEi Search...

Gene expression databases

Bgeei Q8WXX7.
CleanExi HS_AUTS2.
ExpressionAtlasi Q8WXX7. baseline and differential.
Genevestigatori Q8WXX7.

Family and domain databases

InterProi IPR023246. AUTS2.
[Graphical view ]
PRINTSi PR02044. FIBROSIN1LPF.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins."
    Sultana R., Yu C.-H., Yu J., Munson J., Chen D., Hua W., Estes A., Cortes F., de la Barra F., Yu D., Haider S.T., Trask B.J., Green E.D., Raskind W.H., Disteche C.M., Wijsman E., Dawson G., Storm D.R., Schellenberg G.D., Villacres E.C.
    Genomics 80:129-134(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, VARIANT SER-303.
  2. "Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus."
    Beunders G., Voorhoeve E., Golzio C., Pardo L.M., Rosenfeld J.A., Talkowski M.E., Simonic I., Lionel A.C., Vergult S., Pyatt R.E., van de Kamp J., Nieuwint A., Weiss M.M., Rizzu P., Verwer L.E., van Spaendonk R.M., Shen Y., Wu B.L.
    , Yu T., Yu Y., Chiang C., Gusella J.F., Lindgren A.M., Morton C.C., van Binsbergen E., Bulk S., van Rossem E., Vanakker O., Armstrong R., Park S.M., Greenhalgh L., Maye U., Neill N.J., Abbott K.M., Sell S., Ladda R., Farber D.M., Bader P.I., Cushing T., Drautz J.M., Konczal L., Nash P., de Los Reyes E., Carter M.T., Hopkins E., Marshall C.R., Osborne L.R., Gripp K.W., Thrush D.L., Hashimoto S., Gastier-Foster J.M., Astbury C., Ylstra B., Meijers-Heijboer H., Posthuma D., Menten B., Mortier G., Scherer S.W., Eichler E.E., Girirajan S., Katsanis N., Groffen A.J., Sistermans E.A.
    Am. J. Hum. Genet. 92:210-220(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 5), INVOLVEMENT IN MRD26, TISSUE SPECIFICITY.
  3. "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro."
    Ishikawa K., Nagase T., Nakajima D., Seki N., Ohira M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 4:307-313(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Brain.
  4. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.
  5. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "Human chromosome 7: DNA sequence and biology."
    Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
    , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.-C.
    Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
    Tissue: Muscle and Placenta.
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1233, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1198, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiAUTS2_HUMAN
AccessioniPrimary (citable) accession number: Q8WXX7
Secondary accession number(s): A4D1Y9
, L7QET3, L7QF75, Q5D049, Q6PJU5, Q9Y4F2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3