Q8WXU1 (Q8WXU1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
BCL2-associated X protein EMBL AAL73333.1

Gene names

Name:

BAX EMBL AAL73333.1

Organism

Homo sapiens (Human) EMBL AAL73333.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	24 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	B cell apoptotic process Inferred from electronic annotation. Source: Compara B cell homeostasis Inferred from electronic annotation. Source: Compara B cell homeostatic proliferation Inferred from electronic annotation. Source: Compara B cell negative selection Inferred from electronic annotation. Source: Compara Sertoli cell proliferation Inferred from electronic annotation. Source: Compara T cell homeostatic proliferation Inferred from electronic annotation. Source: Compara activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c Inferred from electronic annotation. Source: Compara blood vessel remodeling Inferred from electronic annotation. Source: Compara cellular response to UV Inferred from electronic annotation. Source: Compara cellular response to organic substance Inferred from electronic annotation. Source: Compara cerebral cortex development Inferred from electronic annotation. Source: Compara development of secondary sexual characteristics Inferred from electronic annotation. Source: Compara fertilization Inferred from electronic annotation. Source: Compara germ cell development Inferred from electronic annotation. Source: Compara germ cell programmed cell death Inferred from electronic annotation. Source: Compara glycosphingolipid metabolic process Inferred from electronic annotation. Source: Compara homeostasis of number of cells within a tissue Inferred from electronic annotation. Source: Compara hypothalamus development Inferred from electronic annotation. Source: Compara induction of apoptosis Inferred from electronic annotation. Source: Compara intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Inferred from electronic annotation. Source: Compara kidney development Inferred from electronic annotation. Source: Compara limb morphogenesis Inferred from electronic annotation. Source: Compara myeloid cell homeostasis Inferred from electronic annotation. Source: Compara negative regulation of fibroblast proliferation Inferred from electronic annotation. Source: Compara negative regulation of neuron apoptotic process Inferred from electronic annotation. Source: Compara negative regulation of peptidyl-serine phosphorylation Inferred from electronic annotation. Source: Compara neuron apoptotic process Inferred from electronic annotation. Source: Compara neuron migration Inferred from electronic annotation. Source: Compara nuclear fragmentation involved in apoptotic nuclear change Inferred from electronic annotation. Source: Compara odontogenesis of dentin-containing tooth Inferred from electronic annotation. Source: Compara ovarian follicle development Inferred from electronic annotation. Source: Compara positive regulation of B cell apoptotic process Inferred from electronic annotation. Source: Compara positive regulation of apoptotic process involved in mammary gland involution Inferred from electronic annotation. Source: Compara positive regulation of developmental pigmentation Inferred from electronic annotation. Source: Compara positive regulation of neuron apoptotic process Inferred from electronic annotation. Source: Compara positive regulation of release of sequestered calcium ion into cytosol Inferred from electronic annotation. Source: Compara post-embryonic camera-type eye morphogenesis Inferred from electronic annotation. Source: Compara protein homooligomerization Inferred from electronic annotation. Source: Compara protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Inferred from electronic annotation. Source: Compara reduction of endoplasmic reticulum calcium ion concentration Inferred from electronic annotation. Source: Compara regulation of cell cycle Inferred from electronic annotation. Source: Compara regulation of mammary gland epithelial cell proliferation Inferred from electronic annotation. Source: Compara regulation of nitrogen utilization Inferred from electronic annotation. Source: Compara release of cytochrome c from mitochondria Inferred from electronic annotation. Source: Compara response to DNA damage stimulus Inferred from electronic annotation. Source: Compara response to acid Inferred from electronic annotation. Source: Compara response to axon injury Inferred from electronic annotation. Source: Compara response to gamma radiation Inferred from electronic annotation. Source: Compara response to salt stress Inferred from electronic annotation. Source: Compara response to toxin Inferred from electronic annotation. Source: Compara retina development in camera-type eye Inferred from electronic annotation. Source: Compara retinal cell programmed cell death Inferred from electronic annotation. Source: Compara spermatid differentiation Inferred from electronic annotation. Source: Compara vagina development Inferred from electronic annotation. Source: Compara
Cellular_component	cytosolic part Inferred from electronic annotation. Source: Compara endoplasmic reticulum Inferred from electronic annotation. Source: Compara mitochondrial outer membrane Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	24	1	EMBL AAL73333.1

Sequences

	Sequence		Length	Mass (Da)
	Q8WXU1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 8C3D3E8B7479B798	FASTA	24	2,379
	10 20 MDGSGEQPRG GGPTSSEQIM KTGA

References

[1]	"A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes." Thornborrow E.C., Patel S., Mastropietro A.E., Schwartzfarb E.M., Manfredi J.J. Oncogene 21:990-999(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF339054 Genomic DNA. Translation: AAL73333.1.
IPI	IPI00439209.
UniGene	Hs.624291.
3D structure databases
HSSP	HSSP built from PDB template 1F16 based on UniProtKB Q07812.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8WXU1.
Proteomic databases
PRIDE	Q8WXU1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q8WXU1.
Bgee	Q8WXU1.
Family and domain databases
ProtoNet	Search...
Other
ChiTaRS	BAX. human.

Entry information

Entry name

Q8WXU1_HUMAN

Accession

Primary (citable) accession number: Q8WXU1

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	April 3, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.