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Q8WXL0

- Q8WXL0_HUMAN

UniProt

Q8WXL0 - Q8WXL0_HUMAN

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Protein
Submitted name: Luteinizing hormone beta subunit
Gene
LHB
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Keywords - Molecular functioni

HormoneUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Luteinizing hormone beta subunitImported
Gene namesi
Name:LHBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Secreted By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotations

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiQ8WXL0.
BgeeiQ8WXL0.

Structurei

3D structure databases

ProteinModelPortaliQ8WXL0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOVERGENiHBG006698.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiIPR029034. Cystine-knot_cytokine.
IPR006208. Glyco_hormone_CN.
IPR001545. Gonadotropin_bsu.
IPR018245. Gonadotropin_bsu_CS.
[Graphical view]
PANTHERiPTHR11515. PTHR11515. 1 hit.
PfamiPF00007. Cys_knot. 1 hit.
[Graphical view]
SMARTiSM00068. GHB. 1 hit.
[Graphical view]
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiPS00261. GLYCO_HORMONE_BETA_1. 1 hit.
PS00689. GLYCO_HORMONE_BETA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8WXL0-1 [UniParc]FASTAAdd to Basket

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GLLLLLLLSM GGAWASREPL RPWCHPINAI LAVEKEGCPV CITVNTTICA    50
GYCPTMMRVL QAVLPPLPQV VCTYRDVRFE SIRLPGCPRG VDPVVSFPVA 100
LSCRCGPCRR STSDCGGPKD HPLTCDHPQL SGLLFL 136
Length:136
Mass (Da):14,712
Last modified:March 1, 2002 - v1
Checksum:iFE5451852A45054E
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF397591 Genomic DNA. Translation: AAL69719.1.
UniGeneiHs.154704.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF397591 Genomic DNA. Translation: AAL69719.1 .
UniGenei Hs.154704.

3D structure databases

ProteinModelPortali Q8WXL0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG006698.

Gene expression databases

ArrayExpressi Q8WXL0.
Bgeei Q8WXL0.

Family and domain databases

Gene3Di 2.10.90.10. 1 hit.
InterProi IPR029034. Cystine-knot_cytokine.
IPR006208. Glyco_hormone_CN.
IPR001545. Gonadotropin_bsu.
IPR018245. Gonadotropin_bsu_CS.
[Graphical view ]
PANTHERi PTHR11515. PTHR11515. 1 hit.
Pfami PF00007. Cys_knot. 1 hit.
[Graphical view ]
SMARTi SM00068. GHB. 1 hit.
[Graphical view ]
SUPFAMi SSF57501. SSF57501. 1 hit.
PROSITEi PS00261. GLYCO_HORMONE_BETA_1. 1 hit.
PS00689. GLYCO_HORMONE_BETA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Chorionic gonadotropin has a recent origin within primates and an evolutionary history of selection."
    Maston G.A., Ruvolo M.
    Mol. Biol. Evol. 19:320-335(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8WXL0_HUMAN
AccessioniPrimary (citable) accession number: Q8WXL0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: July 9, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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