Q8WXL0 (Q8WXL0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Luteinizing hormone beta subunit EMBL AAL69719.1

Gene names

Name:

LHB EMBL AAL69719.1

Organism

Homo sapiens (Human) EMBL AAL69719.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	136 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Secreted By similarity RuleBase RU004069.
Sequence similarities	Belongs to the glycoprotein hormones subunit beta family. RuleBase RU004069

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS001545
Molecular function	Hormone RuleBase RU004069 SAAS SAAS001545
PTM	Disulfide bond SAAS SAAS001545
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAL69719.1

Sequences

	Sequence		Length	Mass (Da)
	Q8WXL0 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: FE5451852A45054E	FASTA	136	14,712
	10 20 30 40 50 60 GLLLLLLLSM GGAWASREPL RPWCHPINAI LAVEKEGCPV CITVNTTICA GYCPTMMRVL 70 80 90 100 110 120 QAVLPPLPQV VCTYRDVRFE SIRLPGCPRG VDPVVSFPVA LSCRCGPCRR STSDCGGPKD 130 HPLTCDHPQL SGLLFL

References

[1]	"Chorionic gonadotropin has a recent origin within primates and an evolutionary history of selection." Maston G.A., Ruvolo M. Mol. Biol. Evol. 19:320-335(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF397591 Genomic DNA. Translation: AAL69719.1.
IPI	IPI00000854.
UniGene	Hs.154704.
3D structure databases
HSSP	HSSP built from PDB template 1HCN based on UniProtKB P01233.
ProteinModelPortal	Q8WXL0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8WXL0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG006698.
Gene expression databases
ArrayExpress	Q8WXL0.
Bgee	Q8WXL0.
Family and domain databases
InterPro	IPR006208. Cys_knot. IPR001545. Gonadotropin_bsu. IPR018245. Gonadotropin_bsu_CS. [Graphical view]
PANTHER	PTHR11515. PTHR11515. 1 hit.
Pfam	PF00007. Cys_knot. 1 hit. [Graphical view]
SMART	SM00068. GHB. 1 hit. [Graphical view]
PROSITE	PS00261. GLYCO_HORMONE_BETA_1. 1 hit. PS00689. GLYCO_HORMONE_BETA_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8WXL0_HUMAN

Accession

Primary (citable) accession number: Q8WXL0

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	April 3, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.