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Q8WXL0 (Q8WXL0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:LHB EMBL AAL69719.1
OrganismHomo sapiens (Human) EMBL AAL69719.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length136 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Secreted By similarity RuleBase RU004069 SAAS SAAS001545.

Sequence similarities

Belongs to the glycoprotein hormones subunit beta family. RuleBase RU004069

Ontologies

Keywords
   Cellular componentSecreted SAAS SAAS006208
   Molecular functionHormone RuleBase RU004069 SAAS SAAS001545
   PTMDisulfide bond SAAS SAAS006208
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAL69719.1

Sequences

Sequence LengthMass (Da)Tools
Q8WXL0 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: FE5451852A45054E

FASTA13614,712
        10         20         30         40         50         60 
GLLLLLLLSM GGAWASREPL RPWCHPINAI LAVEKEGCPV CITVNTTICA GYCPTMMRVL 

        70         80         90        100        110        120 
QAVLPPLPQV VCTYRDVRFE SIRLPGCPRG VDPVVSFPVA LSCRCGPCRR STSDCGGPKD 

       130 
HPLTCDHPQL SGLLFL 

« Hide

References

[1]"Chorionic gonadotropin has a recent origin within primates and an evolutionary history of selection."
Maston G.A., Ruvolo M.
Mol. Biol. Evol. 19:320-335(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF397591 Genomic DNA. Translation: AAL69719.1.
UniGeneHs.154704.

3D structure databases

ProteinModelPortalQ8WXL0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG006698.

Gene expression databases

ArrayExpressQ8WXL0.
BgeeQ8WXL0.

Family and domain databases

Gene3D2.10.90.10. 1 hit.
InterProIPR029034. Cystine-knot_cytokine.
IPR006208. Glyco_hormone_CN.
IPR001545. Gonadotropin_bsu.
IPR018245. Gonadotropin_bsu_CS.
[Graphical view]
PANTHERPTHR11515. PTHR11515. 1 hit.
PfamPF00007. Cys_knot. 1 hit.
[Graphical view]
SMARTSM00068. GHB. 1 hit.
[Graphical view]
SUPFAMSSF57501. SSF57501. 1 hit.
PROSITEPS00261. GLYCO_HORMONE_BETA_1. 1 hit.
PS00689. GLYCO_HORMONE_BETA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8WXL0_HUMAN
AccessionPrimary (citable) accession number: Q8WXL0
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: July 9, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.