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Q8WWZ7

- ABCA5_HUMAN

UniProt

Q8WWZ7 - ABCA5_HUMAN

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Protein

ATP-binding cassette sub-family A member 5

Gene

ABCA5

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

May play a role in the processing of autolysosomes.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi514 – 5218ATP 1PROSITE-ProRule annotation
Nucleotide bindingi1333 – 13408ATP 2PROSITE-ProRule annotation

GO - Molecular functioni

  1. ATPase activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. cholesterol efflux Source: BHF-UCL
  2. high-density lipoprotein particle remodeling Source: BHF-UCL
  3. negative regulation of macrophage derived foam cell differentiation Source: BHF-UCL
  4. reverse cholesterol transport Source: BHF-UCL
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Protein family/group databases

TCDBi3.A.1.211.9. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-binding cassette sub-family A member 5
Gene namesi
Name:ABCA5
Synonyms:KIAA1888
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:35. ABCA5.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei32 – 5221HelicalSequence AnalysisAdd
BLAST
Transmembranei220 – 24021HelicalSequence AnalysisAdd
BLAST
Transmembranei264 – 28421HelicalSequence AnalysisAdd
BLAST
Transmembranei297 – 31721HelicalSequence AnalysisAdd
BLAST
Transmembranei328 – 34821HelicalSequence AnalysisAdd
BLAST
Transmembranei355 – 37521HelicalSequence AnalysisAdd
BLAST
Transmembranei396 – 41621HelicalSequence AnalysisAdd
BLAST
Transmembranei866 – 88621HelicalSequence AnalysisAdd
BLAST
Transmembranei967 – 98721HelicalSequence AnalysisAdd
BLAST
Transmembranei1021 – 104121HelicalSequence AnalysisAdd
BLAST
Transmembranei1071 – 109121HelicalSequence AnalysisAdd
BLAST
Transmembranei1102 – 112221HelicalSequence AnalysisAdd
BLAST
Transmembranei1139 – 115921HelicalSequence AnalysisAdd
BLAST
Transmembranei1169 – 118921HelicalSequence AnalysisAdd
BLAST
Transmembranei1207 – 122721HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. Golgi apparatus Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
  3. late endosome Source: BHF-UCL
  4. lysosome Source: BHF-UCL
Complete GO annotation...

Keywords - Cellular componenti

Endosome, Golgi apparatus, Lysosome, Membrane

Pathology & Biotechi

Organism-specific databases

Orphaneti2026. Gingival fibromatosis-hypertrichosis syndrome.
PharmGKBiPA24380.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 16421642ATP-binding cassette sub-family A member 5PRO_0000250669Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi86 – 861N-linked (GlcNAc...)Sequence Analysis
Glycosylationi458 – 4581N-linked (GlcNAc...)Sequence Analysis
Glycosylationi996 – 9961N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ8WWZ7.
PaxDbiQ8WWZ7.
PRIDEiQ8WWZ7.

PTM databases

PhosphoSiteiQ8WWZ7.

Expressioni

Tissue specificityi

Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.2 Publications

Developmental stagei

Expressed in fetal liver, kidney and brain.1 Publication

Gene expression databases

BgeeiQ8WWZ7.
CleanExiHS_ABCA5.
ExpressionAtlasiQ8WWZ7. baseline and differential.
GenevestigatoriQ8WWZ7.

Organism-specific databases

HPAiHPA022032.

Interactioni

Protein-protein interaction databases

BioGridi117024. 2 interactions.
IntActiQ8WWZ7. 2 interactions.
STRINGi9606.ENSP00000319766.

Structurei

3D structure databases

ProteinModelPortaliQ8WWZ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini478 – 713236ABC transporter 1PROSITE-ProRule annotationAdd
BLAST
Domaini1290 – 1533244ABC transporter 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1131.
GeneTreeiENSGT00760000118965.
HOGENOMiHOG000231057.
HOVERGENiHBG079884.
InParanoidiQ8WWZ7.
KOiK05648.
OrthoDBiEOG73Z2SB.
PhylomeDBiQ8WWZ7.
TreeFamiTF105192.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR19229. PTHR19229. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8WWZ7-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSTAIREVGV WRQTRTLLLK NYLIKCRTKK SSVQEILFPL FFLFWLILIS
60 70 80 90 100
MMHPNKKYEE VPNIELNPMD KFTLSNLILG YTPVTNITSS IMQKVSTDHL
110 120 130 140 150
PDVIITEEYT NEKEMLTSSL SKPSNFVGVV FKDSMSYELR FFPDMIPVSS
160 170 180 190 200
IYMDSRAGCS KSCEAAQYWS SGFTVLQASI DAAIIQLKTN VSLWKELEST
210 220 230 240 250
KAVIMGETAV VEIDTFPRGV ILIYLVIAFS PFGYFLAIHI VAEKEKKIKE
260 270 280 290 300
FLKIMGLHDT AFWLSWVLLY TSLIFLMSLL MAVIATASLL FPQSSSIVIF
310 320 330 340 350
LLFFLYGLSS VFFALMLTPL FKKSKHVGIV EFFVTVAFGF IGLMIILIES
360 370 380 390 400
FPKSLVWLFS PFCHCTFVIG IAQVMHLEDF NEGASFSNLT AGPYPLIITI
410 420 430 440 450
IMLTLNSIFY VLLAVYLDQV IPGEFGLRRS SLYFLKPSYW SKSKRNYEEL
460 470 480 490 500
SEGNVNGNIS FSEIIEPVSS EFVGKEAIRI SGIQKTYRKK GENVEALRNL
510 520 530 540 550
SFDIYEGQIT ALLGHSGTGK STLMNILCGL CPPSDGFASI YGHRVSEIDE
560 570 580 590 600
MFEARKMIGI CPQLDIHFDV LTVEENLSIL ASIKGIPANN IIQEVQKVLL
610 620 630 640 650
DLDMQTIKDN QAKKLSGGQK RKLSLGIAVL GNPKILLLDE PTAGMDPCSR
660 670 680 690 700
HIVWNLLKYR KANRVTVFST HFMDEADILA DRKAVISQGM LKCVGSSMFL
710 720 730 740 750
KSKWGIGYRL SMYIDKYCAT ESLSSLVKQH IPGATLLQQN DQQLVYSLPF
760 770 780 790 800
KDMDKFSGLF SALDSHSNLG VISYGVSMTT LEDVFLKLEV EAEIDQADYS
810 820 830 840 850
VFTQQPLEEE MDSKSFDEME QSLLILSETK AALVSTMSLW KQQMYTIAKF
860 870 880 890 900
HFFTLKRESK SVRSVLLLLL IFFTVQIFMF LVHHSFKNAV VPIKLVPDLY
910 920 930 940 950
FLKPGDKPHK YKTSLLLQNS ADSDISDLIS FFTSQNIMVT MINDSDYVSV
960 970 980 990 1000
APHSAALNVM HSEKDYVFAA VFNSTMVYSL PILVNIISNY YLYHLNVTET
1010 1020 1030 1040 1050
IQIWSTPFFQ EITDIVFKIE LYFQAALLGI IVTAMPPYFA MENAENHKIK
1060 1070 1080 1090 1100
AYTQLKLSGL LPSAYWIGQA VVDIPLFFII LILMLGSLLA FHYGLYFYTV
1110 1120 1130 1140 1150
KFLAVVFCLI GYVPSVILFT YIASFTFKKI LNTKEFWSFI YSVAALACIA
1160 1170 1180 1190 1200
ITEITFFMGY TIATILHYAF CIIIPIYPLL GCLISFIKIS WKNVRKNVDT
1210 1220 1230 1240 1250
YNPWDRLSVA VISPYLQCVL WIFLLQYYEK KYGGRSIRKD PFFRNLSTKS
1260 1270 1280 1290 1300
KNRKLPEPPD NEDEDEDVKA ERLKVKELMG CQCCEEKPSI MVSNLHKEYD
1310 1320 1330 1340 1350
DKKDFLLSRK VKKVATKYIS FCVKKGEILG LLGPNGAGKS TIINILVGDI
1360 1370 1380 1390 1400
EPTSGQVFLG DYSSETSEDD DSLKCMGYCP QINPLWPDTT LQEHFEIYGA
1410 1420 1430 1440 1450
VKGMSASDMK EVISRITHAL DLKEHLQKTV KKLPAGIKRK LCFALSMLGN
1460 1470 1480 1490 1500
PQITLLDEPS TGMDPKAKQH MWRAIRTAFK NRKRAAILTT HYMEEAEAVC
1510 1520 1530 1540 1550
DRVAIMVSGQ LRCIGTVQHL KSKFGKGYFL EIKLKDWIEN LEVDRLQREI
1560 1570 1580 1590 1600
QYIFPNASRQ ESFSSILAYK IPKEDVQSLS QSFFKLEEAK HAFAIEEYSF
1610 1620 1630 1640
SQATLEQVFV ELTKEQEEED NSCGTLNSTL WWERTQEDRV VF
Length:1,642
Mass (Da):186,508
Last modified:October 3, 2006 - v2
Checksum:i608809E8539804BF
GO
Isoform 2 (identifier: Q8WWZ7-2) [UniParc]FASTAAdd to Basket

Also known as: V20+16

The sequence of this isoform differs from the canonical sequence as follows:
     922-925: DSDI → GESV
     926-1642: Missing.

Show »
Length:925
Mass (Da):104,364
Checksum:iEF5D6A281832CE47
GO
Isoform 3 (identifier: Q8WWZ7-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-777: Missing.

Note: No experimental confirmation available.

Show »
Length:865
Mass (Da):99,273
Checksum:iF0A7BF87007E321F
GO

Sequence cautioni

The sequence BAB71700.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1215 – 12151Y → H in BAB71208. (PubMed:14702039)Curated
Sequence conflicti1357 – 13571V → I in CAB93535. (PubMed:12504089)Curated
Sequence conflicti1366 – 13661T → S in CAB93535. (PubMed:12504089)Curated
Sequence conflicti1371 – 13711D → G in BAB71208. (PubMed:14702039)Curated
Sequence conflicti1419 – 14191A → G in BAB71208. (PubMed:14702039)Curated
Sequence conflicti1523 – 15231K → R in BAB71208. (PubMed:14702039)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti93 – 931Q → K.
Corresponds to variant rs12383 [ dbSNP | Ensembl ].
VAR_027571
Natural varianti178 – 1781A → T.1 Publication
Corresponds to variant rs11544715 [ dbSNP | Ensembl ].
VAR_048128
Natural varianti484 – 4841Q → R.1 Publication
Corresponds to variant rs17686569 [ dbSNP | Ensembl ].
VAR_027572
Natural varianti753 – 7531M → V.
Corresponds to variant rs9898003 [ dbSNP | Ensembl ].
VAR_027573
Natural varianti832 – 8321A → S.3 Publications
Corresponds to variant rs536009 [ dbSNP | Ensembl ].
VAR_027574
Natural varianti960 – 9601M → V.1 Publication
Corresponds to variant rs557491 [ dbSNP | Ensembl ].
VAR_027575
Natural varianti1260 – 12601D → G.
Corresponds to variant rs11544716 [ dbSNP | Ensembl ].
VAR_048129

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 777777Missing in isoform 3. 1 PublicationVSP_020690Add
BLAST
Alternative sequencei922 – 9254DSDI → GESV in isoform 2. 1 PublicationVSP_020691
Alternative sequencei926 – 1642717Missing in isoform 2. 1 PublicationVSP_020692Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY028897 mRNA. Translation: AAK30022.1.
AJ275973 mRNA. Translation: CAB93535.3.
AJ512612 mRNA. Translation: CAD54757.1.
AK056533 mRNA. Translation: BAB71208.1.
AK058170 mRNA. Translation: BAB71700.1. Different initiation.
AB067475 mRNA. Translation: BAB67781.1.
CCDSiCCDS11685.1. [Q8WWZ7-1]
RefSeqiNP_061142.2. NM_018672.4. [Q8WWZ7-1]
NP_758424.1. NM_172232.3. [Q8WWZ7-1]
UniGeneiHs.731824.

Genome annotation databases

EnsembliENST00000392676; ENSP00000376443; ENSG00000154265. [Q8WWZ7-1]
ENST00000588877; ENSP00000467882; ENSG00000154265. [Q8WWZ7-1]
GeneIDi23461.
KEGGihsa:23461.
UCSCiuc002jib.2. human. [Q8WWZ7-3]
uc002jic.2. human. [Q8WWZ7-1]
uc002jih.2. human. [Q8WWZ7-2]

Polymorphism databases

DMDMi115503762.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

ABCMdb

Database for mutations in ABC proteins

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY028897 mRNA. Translation: AAK30022.1 .
AJ275973 mRNA. Translation: CAB93535.3 .
AJ512612 mRNA. Translation: CAD54757.1 .
AK056533 mRNA. Translation: BAB71208.1 .
AK058170 mRNA. Translation: BAB71700.1 . Different initiation.
AB067475 mRNA. Translation: BAB67781.1 .
CCDSi CCDS11685.1. [Q8WWZ7-1 ]
RefSeqi NP_061142.2. NM_018672.4. [Q8WWZ7-1 ]
NP_758424.1. NM_172232.3. [Q8WWZ7-1 ]
UniGenei Hs.731824.

3D structure databases

ProteinModelPortali Q8WWZ7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 117024. 2 interactions.
IntActi Q8WWZ7. 2 interactions.
STRINGi 9606.ENSP00000319766.

Chemistry

DrugBanki DB00864. Tacrolimus.

Protein family/group databases

TCDBi 3.A.1.211.9. the atp-binding cassette (abc) superfamily.

PTM databases

PhosphoSitei Q8WWZ7.

Polymorphism databases

DMDMi 115503762.

Proteomic databases

MaxQBi Q8WWZ7.
PaxDbi Q8WWZ7.
PRIDEi Q8WWZ7.

Protocols and materials databases

DNASUi 23461.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000392676 ; ENSP00000376443 ; ENSG00000154265 . [Q8WWZ7-1 ]
ENST00000588877 ; ENSP00000467882 ; ENSG00000154265 . [Q8WWZ7-1 ]
GeneIDi 23461.
KEGGi hsa:23461.
UCSCi uc002jib.2. human. [Q8WWZ7-3 ]
uc002jic.2. human. [Q8WWZ7-1 ]
uc002jih.2. human. [Q8WWZ7-2 ]

Organism-specific databases

CTDi 23461.
GeneCardsi GC17M067240.
HGNCi HGNC:35. ABCA5.
HPAi HPA022032.
MIMi 612503. gene.
neXtProti NX_Q8WWZ7.
Orphaneti 2026. Gingival fibromatosis-hypertrichosis syndrome.
PharmGKBi PA24380.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG1131.
GeneTreei ENSGT00760000118965.
HOGENOMi HOG000231057.
HOVERGENi HBG079884.
InParanoidi Q8WWZ7.
KOi K05648.
OrthoDBi EOG73Z2SB.
PhylomeDBi Q8WWZ7.
TreeFami TF105192.

Miscellaneous databases

ChiTaRSi ABCA5. human.
GenomeRNAii 23461.
NextBioi 45765.
PROi Q8WWZ7.
SOURCEi Search...

Gene expression databases

Bgeei Q8WWZ7.
CleanExi HS_ABCA5.
ExpressionAtlasi Q8WWZ7. baseline and differential.
Genevestigatori Q8WWZ7.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
InterProi IPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR19229. PTHR19229. 1 hit.
Pfami PF00005. ABC_tran. 2 hits.
[Graphical view ]
SMARTi SM00382. AAA. 2 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identifying and characterizing a five-gene cluster of ATP-binding cassette transporters mapping to human chromosome 17q24: a new subgroup within the ABCA subfamily."
    Arnould I., Schriml L.M., Prades C., Lachtermacher-Triunfol M., Schneider T., Maintoux C., Lemoine C., Debono D., Devaud C., Naudin L., Bauche S., Annat M., Annilo T., Allikmets R., Gold B., Denefle P., Rosier M., Dean M.
    GeneScreen 1:157-164(2001)
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT SER-832, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
    Tissue: Testis.
  2. "Cloning of human and rat ABCA5/Abca5 and detection of a human splice variant."
    Petry F., Kotthaus A., Hirsch-Ernst K.I.
    Biochem. Biophys. Res. Commun. 300:343-350(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), TISSUE SPECIFICITY, VARIANTS THR-178; ARG-484 AND SER-832.
    Tissue: Hepatoma and Testis.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1187-1642 (ISOFORM 1), VARIANT SER-832.
    Tissue: Teratocarcinoma and Testis.
  4. "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins."
    Nagase T., Kikuno R., Ohara O.
    DNA Res. 8:179-187(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 906-1642 (ISOFORM 1), VARIANT VAL-960.
    Tissue: Brain.

Entry informationi

Entry nameiABCA5_HUMAN
AccessioniPrimary (citable) accession number: Q8WWZ7
Secondary accession number(s): Q8IVJ2
, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 3, 2006
Last modified: October 29, 2014
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3