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Q8WWN6

- Q8WWN6_HUMAN

UniProt

Q8WWN6 - Q8WWN6_HUMAN

Protein
Submitted name:

Nav1.5

Gene

SCN5A

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. ion channel activity Source: InterPro

    Keywords - Molecular functioni

    Ion channelUniRule annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Nav1.5Imported
    Gene namesi
    Name:SCN5AImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8WWN6.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1406914.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8WWN6.
    SMRiQ8WWN6. Positions 3-88.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000197795.

    Family and domain databases

    InterProiIPR005821. Ion_trans_dom.
    [Graphical view]
    PfamiPF00520. Ion_trans. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8WWN6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAQHDPPPWT KYVEYVSENI KLGNLSALRT FRVLRALKTI SVIPGLKTIV    50
    GALIQSVKKL ADVMVLTVFC LSVFALIGLQ LFMGNLRHKC VRNFTALNGT 100
    NGSVEADGLV WES 113
    Length:113
    Mass (Da):12,445
    Last modified:March 1, 2002 - v1
    Checksum:i2A0200A0BFBE0353
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei113 – 1131Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ310893 mRNA. Translation: CAC84525.1.
    UniGeneiHs.517898.

    Genome annotation databases

    UCSCiuc010hhl.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ310893 mRNA. Translation: CAC84525.1 .
    UniGenei Hs.517898.

    3D structure databases

    ProteinModelPortali Q8WWN6.
    SMRi Q8WWN6. Positions 3-88.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1406914.

    Proteomic databases

    PRIDEi Q8WWN6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc010hhl.1. human.

    Phylogenomic databases

    HOGENOMi HOG000197795.

    Family and domain databases

    InterProi IPR005821. Ion_trans_dom.
    [Graphical view ]
    Pfami PF00520. Ion_trans. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Upregulation of voltage-gated Na+ channel expression and metastatic potential in human breast cancer: Correlative studies on cell lines and biopsy tissues."
      Diss J.K.J., Fraser S.P., Coombes R.C., Djamgoz M.B.A.
      Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Biopsy sample 8Imported.
      Tissue: BreastImported.

    Entry informationi

    Entry nameiQ8WWN6_HUMAN
    AccessioniPrimary (citable) accession number: Q8WWN6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.