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Protein
Submitted name:

Nav1.6

Gene

SCN8A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nav1.6Imported
Gene namesi
Name:SCN8AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ8WWN3.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000346534.

Family & Domainsi

Family and domain databases

InterProiIPR001696. Na_channel_asu.
[Graphical view]
PANTHERiPTHR10037:SF132. PTHR10037:SF132. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8WWN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VNLFAGKYHY CFNETSEIRF EIEDVNNKTE CEKLMEGNNT EIRWKNVKIN
60
FDNVGAGYLA LL
Length:62
Mass (Da):7,247
Last modified:March 1, 2002 - v1
Checksum:i9ACE7C630B9B2E6B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei62 – 621Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ310898 mRNA. Translation: CAC84538.1.
UniGeneiHs.436550.
Hs.710638.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ310898 mRNA. Translation: CAC84538.1.
UniGeneiHs.436550.
Hs.710638.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000346534.

Chemistry

BindingDBiQ8WWN3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

ChiTaRSiSCN8A. human.

Gene expression databases

BgeeiQ8WWN3.

Family and domain databases

InterProiIPR001696. Na_channel_asu.
[Graphical view]
PANTHERiPTHR10037:SF132. PTHR10037:SF132. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Upregulation of voltage-gated Na+ channel expression and metastatic potential in human breast cancer: Correlative studies on cell lines and biopsy tissues."
    Diss J.K.J., Fraser S.P., Coombes R.C., Djamgoz M.B.A.
    Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8WWN3_HUMAN
AccessioniPrimary (citable) accession number: Q8WWN3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: June 24, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.