Reviewed, UniProtKB/Swiss-Prot Q8WWK9 (CKAP2_HUMAN)

Names and origin

Protein names

Recommended name:
    Cytoskeleton-associated protein 2
Alternative name(s):
    Tumor- and microtubule-associated protein
    CTCL tumor antigen se20-10

Gene names

Name:	CKAP2
Synonyms:	LB1, TMAP

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	683 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner By similarity. UniProtKB Q3V1H1
Subunit structure	Associates with alpha- and beta-tubulins By similarity.
Subcellular location	Cytoplasm › cytoskeleton. Cytoplasm › cytoskeleton. Cytoplasm › cytoskeleton › spindle. Cytoplasm › cytoskeleton › spindle pole. Note: Contrary to the ectopically expressed protein, endogenous CKAP2 does not colocalize with microtubules in G1, S and early G2. At late G2 and prophase after separation of duplicated centrosomes, colocalizes with gamma-tubulin and centrosome-proximal microtubules. From prometaphase through anaphase B, colocalizes with mitotic spindle poles and spindle microtubules. During cytokinesis, absent from midbody microtubules. Ref.1 Ref.3 Ref.10
Tissue specificity	Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney. Ref.1
Developmental stage	Present at the G1/S boundary. Accumulates as cells progress from S to G2 into mitosis. Rapidly degraded during mitosis exit by CDH1-activated anaphase promoting complex/cyclosome (APC/C). Ref.10
Induction	Up-regulated in primary human gastric cancers. Ref.3
Sequence similarities	Belongs to the CKAP2 family.
Sequence caution	The sequence AAG33675.1 differs from that shown. Reason: Frameshift at position 607. The sequence AAI05807.1 differs from that shown. Reason: Miscellaneous discrepancy. Contaminating sequence. Potential poly-A sequence.

Ontologies

Keywords
Biological process	Apoptosis Cell cycle
Cellular component	Cytoplasm Cytoskeleton Microtubule
Coding sequence diversity	Alternative splicing Polymorphism
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	apoptosis Inferred from electronic annotation. Source: UniProtKB-KW cell cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from direct assay. Source: HPA microtubule Inferred from electronic annotation. Source: UniProtKB-KW spindle Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 Ref.1 Ref.3 Ref.8 (identifier: Q8WWK9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 Ref.6 (identifier: Q8WWK9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-235: Missing.
     496-683: Missing.

Note: No experimental confirmation available.

Isoform 3 Ref.3 (identifier: Q8WWK9-3)

The sequence of this isoform differs from the canonical sequence as follows:
     496-683: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 683	683	Cytoskeleton-associated protein 2		PRO_0000245774
Amino acid modifications
	Modified residue	69	1	Phosphothreonine Ref.13
	Modified residue	209	1	Phosphoserine Ref.13
	Modified residue	211	1	Phosphothreonine Ref.13
	Modified residue	276	1	Phosphoserine Ref.13
	Modified residue	280	1	Phosphothreonine Ref.13
	Modified residue	304	1	Phosphoserine Ref.13
	Modified residue	305	1	Phosphoserine Ref.13
	Modified residue	328	1	Phosphoserine Ref.13
	Modified residue	534	1	Phosphoserine Ref.13 Ref.11
	Modified residue	579	1	Phosphothreonine Ref.11 Ref.14
	Modified residue	582	1	Phosphothreonine Ref.11 Ref.14
	Modified residue	595	1	Phosphoserine Ref.14
	Modified residue	596	1	Phosphothreonine Ref.14
	Modified residue	597	1	Phosphothreonine Ref.13 Ref.11 Ref.14
	Modified residue	599	1	Phosphotyrosine Ref.14
	Modified residue	602	1	Phosphoserine Ref.11 Ref.14
	Modified residue	614	1	Phosphoserine Ref.13 Ref.12
	Modified residue	623	1	Phosphothreonine Ref.11
Natural variations
	Alternative sequence	1 – 235	235	Missing in isoform 2. Ref.6		VSP_052093
	Alternative sequence	496 – 683	188	Missing in isoform 2 and isoform 3. Ref.3 Ref.6		VSP_052094
	Natural variant	236	1	M → K: dbSNP rs35975899. Ref.8		VAR_054018
	Natural variant	323	1	I → V: dbSNP rs7335867. Ref.1 Ref.8 Ref.4 Ref.7 Ref.9		VAR_027005
Experimental info
	Sequence conflict	53	1	Missing in AAL47212. Ref.3
	Sequence conflict	53	1	Missing in AAL47213. Ref.3
	Sequence conflict	53	1	Missing in BAA91788. Ref.4
	Sequence conflict	53	1	Missing in BAB14345. Ref.4
	Sequence conflict	53	1	Missing in CAH71660. Ref.6
	Sequence conflict	53	1	Missing in CAH71661. Ref.6
	Sequence conflict	53	1	Missing in AAI30297. Ref.7
	Sequence conflict	402	1	P → L in CAB66782. Ref.9
	Sequence conflict	494 – 495	2	PI → VR in AAL47213. Ref.3
	Sequence conflict	494 – 495	2	PI → VR in CAH71661. Ref.6
	Sequence conflict	494 – 495	2	PI → VR in AAH10901. Ref.7
	Sequence conflict	531	1	K → Q in BAA91788. Ref.4
	Sequence conflict	531	1	K → R in BAB14345. Ref.4
	Sequence conflict	559	1	F → L in BAB14345. Ref.4
	Sequence conflict	577	1	V → A in BAB14345. Ref.4
	Sequence conflict	643	1	K → R in BAA91788. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 15287A7D860A4B23	FASTA	683	76,987
	10 20 30 40 50 60 MSTPAVPQDL QLPPSQRAQS AFKEQRRQKL KEHLLRRKTL FAYKQENEML SSSRDQRVVT 70 80 90 100 110 120 SEDQVQEGTK VLKLKTKMAD KENMKRPAES KNNTVVGKHC IPLKPSNELT NSTVVIDTHK 130 140 150 160 170 180 PKDSNQTPHL LLTEDDPQSQ HMTLSQAFHL KNNSKKKQMT TEKQKQDANM PKKPVLGSYR 190 200 210 220 230 240 GQIVQSKINS FRKPLQVKDE SSAATKKLSA TIPKATKPQP VNTSSVTVKS NRSSNMTATT 250 260 270 280 290 300 KFVSTTSQNT QLVRPPIRSH HSNTRDTVKQ GISRTSANVT IRKGPHEKEL LQSKTALSSV 310 320 330 340 350 360 KTSSSQGIIR NKTLSRSIAS EVIARPASLS NDKLMEKSEP VDQRRHTAGK AIVDSRSAQP 370 380 390 400 410 420 KETSEERKAR LSEWKAGKGR VLKRPPNSVV TQHEPAGQNE KPVGSFWTTM AEEDEQRLFT 430 440 450 460 470 480 EKVNNTFSEC LNLINEGCPK EDILVTLNDL IKNIPDAKKL VKYWICLALI EPITSPIENI 490 500 510 520 530 540 IAIYEKAILA GAQPIEEMRH TIVDILTMKS QEKANLGENM EKSCASKEEV KEVSIEDTGV 550 560 570 580 590 600 DVDPEKLEME SKLHRNLLFQ DCEKEQDNKT KDPTHDVKTP NTETRTSCLI KYNVSTTPYL 610 620 630 640 650 660 QSVKKKVQFD GTNSAFKELK FLTPVRRSRR LQEKTSKLPD MLKDHYPCVS SLEQLTELGR 670 680 ETDAFVCRPN AALCRVYYEA DTT
	Isoform 2. Checksum: 351AB20CD0FD6669	FASTA	260	28,846
	10 20 30 40 50 60 MTATTKFVST TSQNTQLVRP PIRSHHSNTR DTVKQGISRT SANVTIRKGP HEKELLQSKT 70 80 90 100 110 120 ALSSVKTSSS QGIIRNKTLS RSIASEVIAR PASLSNDKLM EKSEPVDQRR HTAGKAIVDS 130 140 150 160 170 180 RSAQPKETSE ERKARLSEWK AGKGRVLKRP PNSVVTQHEP AGQNEKPVGS FWTTMAEEDE 190 200 210 220 230 240 QRLFTEKVNN TFSECLNLIN EGCPKEDILV TLNDLIKNIP DAKKLVKYWI CLALIEPITS 250 260 PIENIIAIYE KAILAGAQPI
	Isoform 3. Checksum: 54D1BB41418292F7	FASTA	495	55,349
	10 20 30 40 50 60 MSTPAVPQDL QLPPSQRAQS AFKEQRRQKL KEHLLRRKTL FAYKQENEML SSSRDQRVVT 70 80 90 100 110 120 SEDQVQEGTK VLKLKTKMAD KENMKRPAES KNNTVVGKHC IPLKPSNELT NSTVVIDTHK 130 140 150 160 170 180 PKDSNQTPHL LLTEDDPQSQ HMTLSQAFHL KNNSKKKQMT TEKQKQDANM PKKPVLGSYR 190 200 210 220 230 240 GQIVQSKINS FRKPLQVKDE SSAATKKLSA TIPKATKPQP VNTSSVTVKS NRSSNMTATT 250 260 270 280 290 300 KFVSTTSQNT QLVRPPIRSH HSNTRDTVKQ GISRTSANVT IRKGPHEKEL LQSKTALSSV 310 320 330 340 350 360 KTSSSQGIIR NKTLSRSIAS EVIARPASLS NDKLMEKSEP VDQRRHTAGK AIVDSRSAQP 370 380 390 400 410 420 KETSEERKAR LSEWKAGKGR VLKRPPNSVV TQHEPAGQNE KPVGSFWTTM AEEDEQRLFT 430 440 450 460 470 480 EKVNNTFSEC LNLINEGCPK EDILVTLNDL IKNIPDAKKL VKYWICLALI EPITSPIENI 490 IAIYEKAILA GAQPI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of a novel cDNA, encoding a cytoskeletal associated protein, differentially expressed in Diffuse Large B-Cell Lymphomas." Maouche-Chretien L., Deleu N., Badoual C., Fraissignes P., Berger R., Gaulard P., Romeo P.H., Leroy-Viard K. Oncogene 17:1245-1251(1998) [PubMed: 9771967] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, TISSUE SPECIFICITY, VARIANT VAL-323. Tissue: T-cell.
[2]	"Evolutionarily-conserved gene CKAP2,located in region 13q14.3 of the human genome, is frequently rearranged in various tumors." Udina I.G., Baranova A.V., Kompaniytsev A.A., Sulimova G.E. Genetika 37:120-123(2001) [PubMed: 11234418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1).
[3]	"Up-regulation of cytoskeletal-associated protein 2 in primary human gastric adenocarcinomas." Bae C.-D., Sung Y.-S., Jeon S.-M., Suh Y., Yang H.-K., Kim Y.-I., Park K.-H., Choi J., Ahn G., Park J. J. Cancer Res. Clin. Oncol. 129:621-630(2003) [PubMed: 12942315] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3), SUBCELLULAR LOCATION, INDUCTION. Tissue: Cervix carcinoma.
[4]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT VAL-323. Tissue: Teratocarcinoma.
[5]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Testis.
[6]	"The DNA sequence and analysis of human chromosome 13." Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T. Nature 428:522-528(2004) [PubMed: 15057823] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 218-683 (ISOFORM 3), VARIANT VAL-323. Tissue: Bone marrow, Cerebellum and Testis.
[8]	"Serological detection of cutaneous T-cell lymphoma-associated antigens." Eichmueller S., Usener D., Dummer R., Stein A., Thiel D., Schadendorf D. Proc. Natl. Acad. Sci. U.S.A. 98:629-634(2001) [PubMed: 11149944] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 38-683 (ISOFORM 1), VARIANTS LYS-236 AND VAL-323. Tissue: Testis.
[9]	"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B. , Tampe J., Heubner D., Wambutt R., Korn B., Klein M., Poustka A. Genome Res. 11:422-435(2001) [PubMed: 11230166] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 135-683 (ISOFORM 1), VARIANT VAL-323. Tissue: Testis.
[10]	"CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit." Seki A., Fang G. J. Biol. Chem. 282:15103-15113(2007) [PubMed: 17376772] [Abstract] Cited for: SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE.
[11]	"Phosphoproteome analysis of the human mitotic spindle." Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R. Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006) [PubMed: 16565220] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-534; THR-579; THR-582; THR-597; SER-602 AND THR-623, MASS SPECTROMETRY. Tissue: Epithelium.
[12]	"Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra." Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D. J. Proteome Res. 6:4150-4162(2007) [PubMed: 17924679] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-614, MASS SPECTROMETRY. Tissue: Epithelium.
[13]	"Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis." Wang B., Malik R., Nigg E.A., Korner R. Anal. Chem. 80:9526-9533(2008) [PubMed: 19007248] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-69; SER-209; THR-211; SER-276; THR-280; SER-304; SER-305; SER-328; SER-534; THR-597 AND SER-614, MASS SPECTROMETRY.
[14]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed: 18669648] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-579; THR-582; SER-595; THR-596; THR-597; TYR-599 AND SER-602, MASS SPECTROMETRY.
[15]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed: 19690332] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-597 AND SER-602, MASS SPECTROMETRY. Tissue: T-cell.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y15758 mRNA. Translation: CAC17466.1. AJ429398 Genomic DNA. Translation: CAD22295.1. AY062261 mRNA. Translation: AAL47212.1. AY062262 mRNA. Translation: AAL47213.1. AK001611 mRNA. Translation: BAA91788.1. Different initiation. AK022982 mRNA. Translation: BAB14345.1. EF560732 mRNA. Translation: ABQ59042.1. AL359513 Genomic DNA. Translation: CAH71660.2. AL359513 Genomic DNA. Translation: CAH71661.2. BC010901 mRNA. Translation: AAH10901.1. Different initiation. BC105806 mRNA. Translation: AAI05807.1. Sequence problems. BC130296 mRNA. Translation: AAI30297.1. AF177227 mRNA. Translation: AAG33675.1. Frameshift. AL136848 mRNA. Translation: CAB66782.2.
IPI	IPI00071824. IPI00640794. IPI00946815.
RefSeq	NP_001091995.1. NP_060674.3.
UniGene	Hs.444028 Hs.449585
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q8WWK9.
PTM databases
PhosphoSite	Q8WWK9.
Proteomic databases
PRIDE	Q8WWK9.
Genome annotation databases
Ensembl	ENST00000378037; ENSP00000367276; ENSG00000136108; Homo sapiens. [Genome view]
GeneID	26586.
KEGG	hsa:26586.
UCSC	uc001vgt.2. human. uc001vgv.2. human.
Organism-specific databases
CTD	26586.
GeneCards	GC13P051927.
HGNC	HGNC:1990. CKAP2.
HPA	HPA008410.
MIM	611569. gene.
PharmGKB	PA26526.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q8WWK9.
InParanoid	Q8WWK9.
OMA	CLIKYNV.
OrthoDB	EOG9QC3QW.
Gene expression databases
ArrayExpress	Q8WWK9.
Bgee	Q8WWK9.
Genevestigator	Q8WWK9.
GermOnline	ENSG00000136108. Homo sapiens.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	48956.
SOURCE	Search...

Entry information

Entry name

CKAP2_HUMAN

Accession

Primary (citable) accession number: Q8WWK9
Secondary accession number(s): A2BDE0 , A5YM58, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2006
Last sequence update:	March 1, 2002
Last modified:	December 15, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.