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Protein

Uncharacterized protein C10orf82

Gene

C10orf82

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C10orf82
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000165863.16
HGNCiHGNC:28500 C10orf82
neXtProtiNX_Q8WW14

Pathology & Biotechi

Organism-specific databases

DisGeNETi143379
OpenTargetsiENSG00000165863
PharmGKBiPA134919914

Polymorphism and mutation databases

BioMutaiC10orf82
DMDMi221222443

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000898071 – 234Uncharacterized protein C10orf82Add BLAST234

Proteomic databases

PaxDbiQ8WW14
PeptideAtlasiQ8WW14
PRIDEiQ8WW14
ProteomicsDBi74845
74846 [Q8WW14-2]
74847 [Q8WW14-3]

Expressioni

Gene expression databases

BgeeiENSG00000165863
CleanExiHS_C10orf82
ExpressionAtlasiQ8WW14 baseline and differential
GenevisibleiQ8WW14 HS

Organism-specific databases

HPAiHPA043022

Interactioni

Protein-protein interaction databases

BioGridi126799, 6 interactors
IntActiQ8WW14, 6 interactors
STRINGi9606.ENSP00000358212

Structurei

3D structure databases

ProteinModelPortaliQ8WW14
SMRiQ8WW14
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IZQ2 Eukaryota
ENOG4112A7G LUCA
GeneTreeiENSGT00390000017460
HOGENOMiHOG000111692
HOVERGENiHBG107693
InParanoidiQ8WW14
OMAiNCYKDFL
OrthoDBiEOG091G0F26
PhylomeDBiQ8WW14
TreeFamiTF337656

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8WW14-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEPSKTFMRN LPITPGYSGF VPFLSCQGMS KEDDMNHCVK TFQEKTQRYK
60 70 80 90 100
EQLRELCCAV ATAPKLKPVN SEETVLQALH QYNLQYHPLI LECKYVKKPL
110 120 130 140 150
QEPPIPGWAG YLPRAKVTEF GCGTRYTVMA KNCYKDFLEI TERAKKAHLK
160 170 180 190 200
PYEEIYGVSS TKTSAPSPKV LQHEELLPKY PDFSIPDGSC PALGRPLRED
210 220 230
PKTPLTCGCA QRPSIPCSGK MYLEPLSSAK YAEG
Length:234
Mass (Da):26,343
Last modified:March 28, 2018 - v3
Checksum:iB10AB6D67800822A
GO
Isoform 2 (identifier: Q8WW14-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     155-234: Missing.

Show »
Length:154
Mass (Da):17,797
Checksum:i38C00B1F8780EED1
GO
Isoform 3 (identifier: Q8WW14-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     92-110: ECKYVKKPLQEPPIPGWAG → GSSALKPFPLTPGHPCRFS
     111-234: Missing.

Show »
Length:110
Mass (Da):12,473
Checksum:iE0C48F433EE875BD
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_050854124T → M. Corresponds to variant dbSNP:rs11551267Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_03611792 – 110ECKYV…PGWAG → GSSALKPFPLTPGHPCRFS in isoform 3. 1 PublicationAdd BLAST19
Alternative sequenceiVSP_036118111 – 234Missing in isoform 3. 1 PublicationAdd BLAST124
Alternative sequenceiVSP_036119155 – 234Missing in isoform 2. 1 PublicationAdd BLAST80

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097587 mRNA Translation: BAG53491.1
AC016825 Genomic DNA No translation available.
CH471066 Genomic DNA Translation: EAW49444.1
CH471066 Genomic DNA Translation: EAW49445.1
BC021737 mRNA Translation: AAH21737.1
CCDSiCCDS7596.1 [Q8WW14-2]
CCDS81510.1 [Q8WW14-1]
RefSeqiNP_001317071.1, NM_001330142.1 [Q8WW14-1]
NP_653262.1, NM_144661.2 [Q8WW14-2]
XP_016871242.1, XM_017015753.1
XP_016871244.1, XM_017015755.1
UniGeneiHs.121347
Hs.733792

Genome annotation databases

EnsembliENST00000369210; ENSP00000358212; ENSG00000165863 [Q8WW14-2]
ENST00000588184; ENSP00000465712; ENSG00000165863 [Q8WW14-1]
GeneIDi143379
KEGGihsa:143379
UCSCiuc001lcr.3 human [Q8WW14-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCJ082_HUMAN
AccessioniPrimary (citable) accession number: Q8WW14
Secondary accession number(s): B3KUM9, D3DRC3, K7EKP3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: March 28, 2018
Last modified: June 20, 2018
This is version 106 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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