Q8WVP7 (LMBR1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Limb region 1 protein homolog

Alternative name(s):
Differentiation-related gene 14 protein

Gene names

Name:	LMBR1
Synonyms:	C7orf2, DIF14

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	490 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Putative membrane receptor.
Subcellular location	Membrane; Multi-pass membrane protein By similarity.
Tissue specificity	Widely expressed with strongest expression in heart and pancreas. Ref.8
Involvement in disease	Preaxial polydactyly 2 (PPD2) [MIM:174500]: Polydactyly consists of duplication of the distal phalanx. The thumb in PPD2 is usually opposable and possesses a normal metacarpal. Note: The disease is caused by mutations affecting the gene represented in this entry. Disease-causing mutations are located in intron 5 of LMBR1. The mutations do not alter normal LMBR1 expression and function, but disrupt a long-range, cis-regulatory element of SHH expression contained in LMBR1 intron 5 (Ref.10). Ref.10 Acheiropody (ACHP) [MIM:200500]: Very rare condition characterized by bilateral congenital amputations of the hands and feet. The specific malformative phenotype consists of a complete amputation of the distal epiphysis of the humerus, amputation of the tibial diaphysisand aplasia of the radius, ulna, fibulaand of all the bones of the hands and feet. Note: The disease is caused by mutations affecting the gene represented in this entry. Syndactyly 4 (SDTY4) [MIM:186200]: Very rare congenital distal limb malformation characterized by complete bilateral syndactyly (involving all digits 1 to 5). A frequent association with polydactyly (with six metacarpals and six digits) has been reported. Feet are affected occasionally. The condition is inherited as an autosomal dominant trait. Note: The disease is caused by mutations affecting the gene represented in this entry. Disease-causing mutations are located in intron 5 of LMBR1. The mutations do not alter normal LMBR1 expression and function, but disrupt a long-range, cis-regulatory element of SHH expression contained in LMBR1 intron 5. Ref.11
Sequence similarities	Belongs to the LIMR family.
Sequence caution	The sequence AAD43188.1 differs from that shown. Reason: Erroneous initiation. The sequence AAK31345.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB15595.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil Transmembrane Transmembrane helix
Molecular function	Receptor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	embryonic digit morphogenesis Inferred from electronic annotation. Source: Compara
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8WVP7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8WVP7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     205-466: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q8WVP7-3)

The sequence of this isoform differs from the canonical sequence as follows:
     252-253: NG → NVGMLCAGNPEVATGRQVPEEQAGQLLLGKWIQEGGDMIANPR

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 490	490	Limb region 1 protein homolog		PRO_0000053906
Regions
	Topological domain	1 – 19	19	Extracellular Potential
	Transmembrane	20 – 40	21	Helical; Potential
	Topological domain	41 – 62	22	Cytoplasmic Potential
	Transmembrane	63 – 83	21	Helical; Potential
	Topological domain	84 – 110	27	Extracellular Potential
	Transmembrane	111 – 131	21	Helical; Potential
	Topological domain	132 – 151	20	Cytoplasmic Potential
	Transmembrane	152 – 172	21	Helical; Potential
	Topological domain	173 – 187	15	Extracellular Potential
	Transmembrane	188 – 208	21	Helical; Potential
	Topological domain	209 – 291	83	Cytoplasmic Potential
	Transmembrane	292 – 312	21	Helical; Potential
	Topological domain	313 – 339	27	Extracellular Potential
	Transmembrane	340 – 360	21	Helical; Potential
	Topological domain	361 – 383	23	Cytoplasmic Potential
	Transmembrane	384 – 404	21	Helical; Potential
	Topological domain	405 – 426	22	Extracellular Potential
	Transmembrane	427 – 447	21	Helical; Potential
	Topological domain	448 – 490	43	Cytoplasmic Potential
	Coiled coil	250 – 287	38	Potential
Natural variations
	Alternative sequence	205 – 466	262	Missing in isoform 2.		VSP_016888
	Alternative sequence	252 – 253	2	NG → NVGMLCAGNPEVATGRQVPE EQAGQLLLGKWIQEGGDMIA NPR in isoform 3.		VSP_017441
	Natural variant	228	1	T → A. Corresponds to variant rs6957768 [ dbSNP | Ensembl ].		VAR_031900
Experimental info
	Sequence conflict	41	1	R → G in AAK94061. Ref.1
	Sequence conflict	76	1	L → S in AAK94061. Ref.1
	Sequence conflict	96	1	Y → C in CAD39056. Ref.7
	Sequence conflict	349	1	A → V in AAK94061. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 228A0EEF248BAD2C	FASTA	490	55,098
	10 20 30 40 50 60 MEGQDEVSAR EQHFHSQVRE STICFLLFAI LYVVSYFIIT RYKRKSDEQE DEDAIVNRIS 70 80 90 100 110 120 LFLSTFTLAV SAGAVLLLPF SIISNEILLS FPQNYYIQWL NGSLIHGLWN LASLFSNLCL 130 140 150 160 170 180 FVLMPFAFFF LESEGFAGLK KGIRARILET LVMLLLLALL ILGIVWVASA LIDNDAASME 190 200 210 220 230 240 SLYDLWEFYL PYLYSCISLM GCLLLLLCTP VGLSRMFTVM GQLLVKPTIL EDLDEQIYII 250 260 270 280 290 300 TLEEEALQRR LNGLSSSVEY NIMELEQELE NVKTLKTKLE RRKKASAWER NLVYPAVMVL 310 320 330 340 350 360 LLIETSISVL LVACNILCLL VDETAMPKGT RGPGIGNASL STFGFVGAAL EIILIFYLMV 370 380 390 400 410 420 SSVVGFYSLR FFGNFTPKKD DTTMTKIIGN CVSILVLSSA LPVMSRTLGI TRFDLLGDFG 430 440 450 460 470 480 RFNWLGNFYI VLSYNLLFAI VTTLCLVRKF TSAVREELFK ALGLHKLHLP NTSRDSETAK 490 PSVNGHQKAL
	Isoform 2 [UniParc]. Checksum: FD806A8E1EF3E356	FASTA	228	25,836
	10 20 30 40 50 60 MEGQDEVSAR EQHFHSQVRE STICFLLFAI LYVVSYFIIT RYKRKSDEQE DEDAIVNRIS 70 80 90 100 110 120 LFLSTFTLAV SAGAVLLLPF SIISNEILLS FPQNYYIQWL NGSLIHGLWN LASLFSNLCL 130 140 150 160 170 180 FVLMPFAFFF LESEGFAGLK KGIRARILET LVMLLLLALL ILGIVWVASA LIDNDAASME 190 200 210 220 SLYDLWEFYL PYLYSCISLM GCLLLHLPNT SRDSETAKPS VNGHQKAL
	Isoform 3 [UniParc]. Checksum: 01928A8E126C96CA	FASTA	531	59,458
	10 20 30 40 50 60 MEGQDEVSAR EQHFHSQVRE STICFLLFAI LYVVSYFIIT RYKRKSDEQE DEDAIVNRIS 70 80 90 100 110 120 LFLSTFTLAV SAGAVLLLPF SIISNEILLS FPQNYYIQWL NGSLIHGLWN LASLFSNLCL 130 140 150 160 170 180 FVLMPFAFFF LESEGFAGLK KGIRARILET LVMLLLLALL ILGIVWVASA LIDNDAASME 190 200 210 220 230 240 SLYDLWEFYL PYLYSCISLM GCLLLLLCTP VGLSRMFTVM GQLLVKPTIL EDLDEQIYII 250 260 270 280 290 300 TLEEEALQRR LNVGMLCAGN PEVATGRQVP EEQAGQLLLG KWIQEGGDMI ANPRLSSSVE 310 320 330 340 350 360 YNIMELEQEL ENVKTLKTKL ERRKKASAWE RNLVYPAVMV LLLIETSISV LLVACNILCL 370 380 390 400 410 420 LVDETAMPKG TRGPGIGNAS LSTFGFVGAA LEIILIFYLM VSSVVGFYSL RFFGNFTPKK 430 440 450 460 470 480 DDTTMTKIIG NCVSILVLSS ALPVMSRTLG ITRFDLLGDF GRFNWLGNFY IVLSYNLLFA 490 500 510 520 530 IVTTLCLVRK FTSAVREELF KALGLHKLHL PNTSRDSETA KPSVNGHQKA L

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and expression analysis of leukemia cell line K562 differentiation-related gene DIF14." Wang Z., Huang G.-S. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Tissue: Leukemia.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 356-490 (ISOFORM 1). Tissue: Embryo and Hepatoma.
[3]	"Human chromosome 7: DNA sequence and biology." Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S. , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.-C. Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Lung.
[7]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3-490 (ISOFORM 3). Tissue: Amygdala.
[8]	"A physical and transcriptional map of the preaxial polydactyly locus on chromosome 7q36." Heus H.C., Hing A., van Baren M.J., Joosse M., Breedveld G.J., Wang J.C., Burgess A., Donnis-Keller H., Berglund C., Zguricas J., Scherer S.W., Rommens J.M., Oostra B.A., Heutink P. Genomics 57:342-351(1999) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.
[9]	"Acheiropodia is caused by a genomic deletion in C7orf2, the human orthologue of the Lmbr1 gene." Ianakiev P., van Baren M.J., Daly M.J., Toledo S.P., Cavalcanti M.G., Neto J.C., Silveira E.L., Freire-Maia A., Heutink P., Kilpatrick M.W., Tsipouras P. Am. J. Hum. Genet. 68:38-45(2001) [PubMed] [Europe PMC] [Abstract] Cited for: INVOLVEMENT IN ACHEIROPODY.
[10]	"A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly." Lettice L.A., Heaney S.J.H., Purdie L.A., Li L., de Beer P., Oostra B.A., Goode D., Elgar G., Hill R.E., de Graaff E. Hum. Mol. Genet. 12:1725-1735(2003) [PubMed] [Europe PMC] [Abstract] Cited for: ASSOCIATION WITH PPD2.
[11]	"Triphalangeal thumb-polysyndactyly syndrome and syndactyly type IV are caused by genomic duplications involving the long range, limb-specific SHH enhancer." Sun M., Ma F., Zeng X., Liu Q., Zhao X.-L., Wu F.-X., Wu G.-P., Zhang Z.-F., Gu B., Zhao Y.-F., Tian S.-H., Lin B., Kong X.-Y., Zhang X.-L., Yang W., Lo W.H.-Y., Zhang X. J. Med. Genet. 45:589-595(2008) [PubMed] [Europe PMC] [Abstract] Cited for: INVOLVEMENT IN SDTY4.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF348513 mRNA. Translation: AAK31345.1. Different initiation. AF402318 mRNA. Translation: AAK94061.1. AK021727 mRNA. Translation: BAB13880.1. AK026940 mRNA. Translation: BAB15595.1. Different initiation. AC005534 Genomic DNA. Translation: AAD43188.1. Different initiation. AC007075 Genomic DNA. Translation: AAF03516.1. AC007097 Genomic DNA. No translation available. CH236954 Genomic DNA. Translation: EAL23920.1. CH471149 Genomic DNA. Translation: EAX04559.1. BC017663 mRNA. Translation: AAH17663.1. AL834394 mRNA. Translation: CAD39056.1.
IPI	IPI00385238. IPI00386956. IPI00413720.
RefSeq	NP_071903.2. NM_022458.3.
UniGene	Hs.209989.
3D structure databases
ProteinModelPortal	Q8WVP7.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8WVP7. 1 interaction.
STRING	9606.ENSP00000326604.
PTM databases
PhosphoSite	Q8WVP7.
Polymorphism databases
DMDM	74730878.
Proteomic databases
PaxDb	Q8WVP7.
PRIDE	Q8WVP7.
Protocols and materials databases
DNASU	64327.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000353442; ENSP00000326604; ENSG00000105983. ENST00000354505; ENSP00000346500; ENSG00000105983.
GeneID	64327.
KEGG	hsa:64327.
UCSC	uc003wmw.4. human. uc010lqn.3. human.
Organism-specific databases
CTD	64327.
GeneCards	GC07M156473.
HGNC	HGNC:13243. LMBR1.
HPA	HPA016592.
MIM	174500. phenotype. 186200. phenotype. 200500. phenotype. 605522. gene.
neXtProt	NX_Q8WVP7.
Orphanet	295118. Adactyly of foot, bilateral. 295116. Adactyly of foot, unilateral. 3332. Hypoplastic tibiae - postaxial polydactyly. 295150. Polydactyly of a triphalangeal thumb, bilateral. 295148. Polydactyly of a triphalangeal thumb, unilateral. 295071. Radial hemimelia, bilateral. 295069. Radial hemimelia, unilateral. 93405. Syndactyly type 4. 2950. Triphalangeal thumb - polysyndactyly syndrome.
PharmGKB	PA25945.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG246746.
HOVERGEN	HBG072983.
OMA	TAMPKGS.
OrthoDB	EOG4TF0K6.
Gene expression databases
ArrayExpress	Q8WVP7.
Bgee	Q8WVP7.
CleanEx	HS_LMBR1.
Genevestigator	Q8WVP7.
GermOnline	ENSG00000105983. Homo sapiens.
Family and domain databases
InterPro	IPR008075. Lipcalin_1_rcpt. IPR006876. LMBR1-like_membr_prot. [Graphical view]
Pfam	PF04791. LMBR1. 1 hit. [Graphical view]
PRINTS	PR01692. LIPOCALINIMR.
ProtoNet	Search...
Other
ChiTaRS	LMBR1. human.
GenomeRNAi	64327.
NextBio	66253.
SOURCE	Search...

Entry information

Entry name

LMBR1_HUMAN

Accession

Primary (citable) accession number: Q8WVP7
Secondary accession number(s): A4D242 , Q8N3E3, Q96QZ5, Q9H5N0, Q9HAG9, Q9UDN5, Q9Y6U2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	March 1, 2002
Last modified:	May 29, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.