Reviewed, UniProtKB/Swiss-Prot Q8WVP5 (TP8L1_HUMAN)

Names and origin

Protein names

Recommended name:
    Tumor necrosis factor, alpha-induced protein 8-like protein 1

Gene names

Name:

TNFAIP8L1

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the TNFAIP8 family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Tumor necrosis factor, alpha-induced protein 8-like protein 1		PRO_0000285724
Natural variations
	Natural variant	118	1	A → V: dbSNP rs17851549. Ref.2		VAR_032048

Sequences

	Sequence		Length	Mass (Da)
	Q8WVP5-1 [UniParc]. Last modified May 1, 2007. Version 2. Checksum: 352B0E7A2FB6D216	FASTA	186	20,827
	10 20 30 40 50 60 MDTFSTKSLA LQAQKKLLSK MASKAVVAVL VDDTSSEVLD ELYRATREFT RSRKEAQKML 70 80 90 100 110 120 KNLVKVALKL GLLLRGDQLG GEELALLRRF RHRARCLAMT AVSFHQVDFT FDRRVLAAGL 130 140 150 160 170 180 LECRDLLHQA VGPHLTAKSH GRINHVFGHL ADCDFLAALY GPAEPYRSHL RRICEGLGRM LDEGSL

References

[1]

"The DNA sequence and biology of human chromosome 19." Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V. , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M. Nature 428:529-535(2004) [PubMed: 15057824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT VAL-118. Tissue: Lung.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC005339 Genomic DNA. No translation available. BC017672 mRNA. Translation: AAH17672.1.
IPI	IPI00103171.
RefSeq	NP_689575.1.
UniGene	Hs.465643
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8WVP5. 1 interaction.
Proteomic databases
PRIDE	Q8WVP5.
Genome annotation databases
Ensembl	ENSG00000185361. Homo sapiens. [Contig view]
GeneID	126282.
KEGG	hsa:126282.
Organism-specific databases
GeneCards	GC19P004591.
HGNC	HGNC:28279. TNFAIP8L1.
PharmGKB	PA142670722.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q8WVP5.
OMA	Q8WVP5. KEFTRSR.
Gene expression databases
ArrayExpress	Q8WVP5.
Bgee	Q8WVP5.
CleanEx	HS_TNFAIP8L1.
Family and domain databases
InterPro	IPR008477. DUF758. [Graphical view]
PANTHER	PTHR12757. DUF758. 1 hit.
Pfam	PF05527. DUF758. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	81749.

Entry information

Entry name

TP8L1_HUMAN

Accession

Primary (citable) accession number: Q8WVP5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	June 16, 2009
This is version 41 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)