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Q8WVM8

- SCFD1_HUMAN

UniProt

Q8WVM8 - SCFD1_HUMAN

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Protein
Sec1 family domain-containing protein 1
Gene
SCFD1, C14orf163, KIAA0917, STXBP1L2, FKSG23
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi By similarity.

GO - Molecular functioni

  1. protein binding Source: IntAct
  2. syntaxin binding Source: UniProtKB

GO - Biological processi

  1. post-Golgi vesicle-mediated transport Source: UniProtKB
  2. protein transport Source: UniProtKB-KW
  3. regulation of ER to Golgi vesicle-mediated transport Source: UniProtKB
  4. response to hypoxia Source: Ensembl
  5. response to toxic substance Source: UniProtKB
  6. retrograde vesicle-mediated transport, Golgi to ER Source: UniProtKB
  7. vesicle docking involved in exocytosis Source: InterPro
Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sec1 family domain-containing protein 1
Alternative name(s):
SLY1 homolog
Short name:
Sly1p
Syntaxin-binding protein 1-like 2
Gene namesi
Name:SCFD1
Synonyms:C14orf163, KIAA0917, STXBP1L2
ORF Names:FKSG23
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 14

Organism-specific databases

HGNCiHGNC:20726. SCFD1.

Subcellular locationi

GO - Cellular componenti

  1. Golgi cisterna membrane Source: UniProtKB-SubCell
  2. Golgi transport complex Source: Ensembl
  3. Golgi-associated vesicle Source: UniProtKB
  4. cis-Golgi network Source: UniProtKB
  5. endoplasmic reticulum membrane Source: UniProtKB-SubCell
  6. plasma membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134946073.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed2 Publications
Chaini2 – 642641Sec1 family domain-containing protein 1
PRO_0000206287Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine4 Publications
Modified residuei303 – 3031Phosphoserine3 Publications

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ8WVM8.
PaxDbiQ8WVM8.
PRIDEiQ8WVM8.

PTM databases

PhosphoSiteiQ8WVM8.

Expressioni

Gene expression databases

ArrayExpressiQ8WVM8.
BgeeiQ8WVM8.
CleanExiHS_SCFD1.
GenevestigatoriQ8WVM8.

Organism-specific databases

HPAiHPA003579.

Interactioni

Subunit structurei

Interacts with STX17. Interacts with STX5A. Interacts with the COG complex via COG4 By similarity.

Binary interactionsi

WithEntry#Exp.IntActNotes
COG4Q9H9E310EBI-722569,EBI-368382

Protein-protein interaction databases

BioGridi116860. 30 interactions.
IntActiQ8WVM8. 10 interactions.
MINTiMINT-1394008.
STRINGi9606.ENSP00000390783.

Structurei

3D structure databases

ProteinModelPortaliQ8WVM8.
SMRiQ8WVM8. Positions 13-459.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi2 – 1312Poly-Ala
Add
BLAST

Sequence similaritiesi

Belongs to the STXBP/unc-18/SEC1 family.

Phylogenomic databases

eggNOGiCOG5158.
HOVERGENiHBG061536.
OMAiKGKQGKH.
PhylomeDBiQ8WVM8.
TreeFamiTF105740.

Family and domain databases

Gene3Di3.40.50.1910. 2 hits.
InterProiIPR027482. Sec-1-like_dom2.
IPR001619. Sec1-like.
[Graphical view]
PANTHERiPTHR11679. PTHR11679. 1 hit.
PfamiPF00995. Sec1. 1 hit.
[Graphical view]
PIRSFiPIRSF005715. VPS45_Sec1. 1 hit.
SUPFAMiSSF56815. SSF56815. 1 hit.

Sequences (3)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8WVM8-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MAAAAAATAA AAASIRERQT VALKRMLNFN VPHIKNSTGE PVWKVLIYDR    50
FGQDIISPLL SVKELRDMGI TLHLLLHSDR DPIPDVPAVY FVMPTEENID 100
RMCQDLRNQL YESYYLNFIS AISRSKLEDI ANAALAASAV TQVAKVFDQY 150
LNFITLEDDM FVLCNQNKEL VSYRAINRPD ITDTEMETVM DTIVDSLFCF 200
FVTLGAVPII RCSRGTAAEM VAVKLDKKLR ENLRDARNSL FTGDTLGAGQ 250
FSFQRPLLVL VDRNIDLATP LHHTWTYQAL VHDVLDFHLN RVNLEESSGV 300
ENSPAGARPK RKNKKSYDLT PVDKFWQKHK GSPFPEVAES VQQELESYRA 350
QEDEVKRLKS IMGLEGEDEG AISMLSDNTA KLTSAVSSLP ELLEKKRLID 400
LHTNVATAVL EHIKARKLDV YFEYEEKIMS KTTLDKSLLD IISDPDAGTP 450
EDKMRLFLIY YISTQQAPSE ADLEQYKKAL TDAGCNLNPL QYIKQWKAFT 500
KMASAPASYG STTTKPMGLL SRVMNTGSQF VMEGVKNLVL KQQNLPVTRI 550
LDNLMEMKSN PETDDYRYFD PKMLRGNDSS VPRNKNPFQE AIVFVVGGGN 600
YIEYQNLVDY IKGKQGKHIL YGCSELFNAT QFIKQLSQLG QK 642
Length:642
Mass (Da):72,380
Last modified:January 23, 2007 - v4
Checksum:i0340FB9F05CD24CE
GO
Isoform 2 (identifier: Q8WVM8-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-92: Missing.

Show »
Length:550
Mass (Da):62,260
Checksum:iB920BFF92CE3533B
GO
Isoform 3 (identifier: Q8WVM8-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-67: Missing.

Show »
Length:575
Mass (Da):65,061
Checksum:iD661C294F7170C05
GO

Sequence cautioni

The sequence AAD40381.1 differs from that shown. Reason: Frameshift at several positions.
The sequence AAD48586.1 differs from that shown. Reason: Frameshift at several positions.
The sequence AAP97146.1 differs from that shown. Reason: Frameshift at position 5.
The sequence BAA74940.2 differs from that shown. Reason: Erroneous initiation.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti63 – 631K → R.2 Publications
Corresponds to variant rs229150 [ dbSNP | Ensembl ].
VAR_019616

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 9292Missing in isoform 2.
VSP_047070Add
BLAST
Alternative sequencei1 – 6767Missing in isoform 3.
VSP_047071Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti42 – 421V → I in AAG50273. 1 Publication
Sequence conflicti136 – 1372AA → EL in AAD40381. 1 Publication
Sequence conflicti201 – 2066FVTLGA → YGTRGD in AAD48586. 1 Publication
Sequence conflicti201 – 2022FV → YG in AAD40381. 1 Publication
Sequence conflicti201 – 2022FV → YG in AAP97146. 1 Publication
Sequence conflicti206 – 2061A → D in AAP97146. 1 Publication
Sequence conflicti453 – 4531K → N in AAD48586. 1 Publication
Sequence conflicti484 – 4852GC → EM in AAD40381. 1 Publication
Sequence conflicti485 – 4851Missing in AAD48586. 1 Publication
Sequence conflicti562 – 5632ET → KL in AAD40381. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB020724 mRNA. Translation: BAA74940.2. Different initiation.
AF092139 mRNA. Translation: AAD40381.1. Frameshift.
AF110646 mRNA. Translation: AAD48586.1. Frameshift.
AF319958 mRNA. Translation: AAG50273.1.
AF086916 mRNA. Translation: AAP97146.1. Frameshift.
AK290410 mRNA. Translation: BAF83099.1.
AK298622 mRNA. Translation: BAH12830.1.
AK297873 mRNA. Translation: BAH12683.1.
AK316212 mRNA. Translation: BAH14583.1.
AL121852 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW65968.1.
BC017734 mRNA. Translation: AAH17734.1.
AF067205 mRNA. Translation: AAC17907.1.
CCDSiCCDS45092.1. [Q8WVM8-3]
CCDS58308.1. [Q8WVM8-2]
CCDS9639.1. [Q8WVM8-1]
RefSeqiNP_001244305.1. NM_001257376.1. [Q8WVM8-2]
NP_001269961.1. NM_001283032.1.
NP_057190.2. NM_016106.3. [Q8WVM8-1]
NP_878255.1. NM_182835.2. [Q8WVM8-3]
UniGeneiHs.369168.

Genome annotation databases

EnsembliENST00000396629; ENSP00000379870; ENSG00000092108. [Q8WVM8-2]
ENST00000458591; ENSP00000390783; ENSG00000092108. [Q8WVM8-1]
ENST00000544052; ENSP00000443010; ENSG00000092108. [Q8WVM8-3]
GeneIDi23256.
KEGGihsa:23256.
UCSCiuc001wqm.2. human. [Q8WVM8-1]

Polymorphism databases

DMDMi51316882.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB020724 mRNA. Translation: BAA74940.2 . Different initiation.
AF092139 mRNA. Translation: AAD40381.1 . Frameshift.
AF110646 mRNA. Translation: AAD48586.1 . Frameshift.
AF319958 mRNA. Translation: AAG50273.1 .
AF086916 mRNA. Translation: AAP97146.1 . Frameshift.
AK290410 mRNA. Translation: BAF83099.1 .
AK298622 mRNA. Translation: BAH12830.1 .
AK297873 mRNA. Translation: BAH12683.1 .
AK316212 mRNA. Translation: BAH14583.1 .
AL121852 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW65968.1 .
BC017734 mRNA. Translation: AAH17734.1 .
AF067205 mRNA. Translation: AAC17907.1 .
CCDSi CCDS45092.1. [Q8WVM8-3 ]
CCDS58308.1. [Q8WVM8-2 ]
CCDS9639.1. [Q8WVM8-1 ]
RefSeqi NP_001244305.1. NM_001257376.1. [Q8WVM8-2 ]
NP_001269961.1. NM_001283032.1.
NP_057190.2. NM_016106.3. [Q8WVM8-1 ]
NP_878255.1. NM_182835.2. [Q8WVM8-3 ]
UniGenei Hs.369168.

3D structure databases

ProteinModelPortali Q8WVM8.
SMRi Q8WVM8. Positions 13-459.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 116860. 30 interactions.
IntActi Q8WVM8. 10 interactions.
MINTi MINT-1394008.
STRINGi 9606.ENSP00000390783.

PTM databases

PhosphoSitei Q8WVM8.

Polymorphism databases

DMDMi 51316882.

Proteomic databases

MaxQBi Q8WVM8.
PaxDbi Q8WVM8.
PRIDEi Q8WVM8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000396629 ; ENSP00000379870 ; ENSG00000092108 . [Q8WVM8-2 ]
ENST00000458591 ; ENSP00000390783 ; ENSG00000092108 . [Q8WVM8-1 ]
ENST00000544052 ; ENSP00000443010 ; ENSG00000092108 . [Q8WVM8-3 ]
GeneIDi 23256.
KEGGi hsa:23256.
UCSCi uc001wqm.2. human. [Q8WVM8-1 ]

Organism-specific databases

CTDi 23256.
GeneCardsi GC14P031091.
HGNCi HGNC:20726. SCFD1.
HPAi HPA003579.
neXtProti NX_Q8WVM8.
PharmGKBi PA134946073.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5158.
HOVERGENi HBG061536.
OMAi KGKQGKH.
PhylomeDBi Q8WVM8.
TreeFami TF105740.

Miscellaneous databases

ChiTaRSi SCFD1. human.
GeneWikii SCFD1.
GenomeRNAii 23256.
NextBioi 44982.
PROi Q8WVM8.

Gene expression databases

ArrayExpressi Q8WVM8.
Bgeei Q8WVM8.
CleanExi HS_SCFD1.
Genevestigatori Q8WVM8.

Family and domain databases

Gene3Di 3.40.50.1910. 2 hits.
InterProi IPR027482. Sec-1-like_dom2.
IPR001619. Sec1-like.
[Graphical view ]
PANTHERi PTHR11679. PTHR11679. 1 hit.
Pfami PF00995. Sec1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005715. VPS45_Sec1. 1 hit.
SUPFAMi SSF56815. SSF56815. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  2. "Human vesicle transport-related protein gene."
    Song H., Peng Y., Dai M., Huang Q., Mao Y., Zhang Q., Mao M., Fu G., Luo M., Chen J., Hu R.
    Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Pituitary.
  3. "Identification of FKSG23, a vesicle transport-related protein."
    Wang Y.-G., Gong L.
    Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  4. "Cloning of a novel human cDNA homology to R.norvegicus rsly1p mRNA."
    Dai F.Y., Yu L., Ding J.B., Lin W., Yang Y.M., Zhao S.Y.
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3), VARIANT ARG-63.
    Tissue: Heart and Umbilical cord blood.
  6. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ARG-63.
    Tissue: Lymph.
  9. "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
    Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.
    Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-16.
    Tissue: Platelet.
  10. Bienvenut W.V., Gao M., Leug H., Campbell A., Ozanne B.W.
    Submitted (JUL-2009) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 2-16; 125-145; 382-395 AND 502-536, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: Foreskin fibroblast and Prostatic carcinoma.
  11. "Differential display of placental genes."
    Page N.M., Butlin D.J., Manyonda I., Bicknell A.B., Lowry P.J.
    Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 572-642.
    Tissue: Placenta.
  12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  13. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
    Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
    Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-303, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  14. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-303, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  15. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  16. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-303, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  17. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  18. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
    Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
    Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  19. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSCFD1_HUMAN
AccessioniPrimary (citable) accession number: Q8WVM8
Secondary accession number(s): A8K2Z5
, B7Z4U7, B7Z594, O60754, O94990, Q7Z529, Q9BZI3, Q9UNL3, Q9Y6A8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: January 23, 2007
Last modified: September 3, 2014
This is version 120 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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