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Protein
Submitted name:

PRMT3 protein

Gene

PRMT3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein methyltransferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PRMT3 proteinImported
Gene namesi
Name:PRMT3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29462.

PTM / Processingi

Proteomic databases

PRIDEiQ8WUV3.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ8WUV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000198521.
HOVERGENiHBG001793.
KOiK11436.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR025799. Arg_MeTrfase.
IPR010456. Ribosomal-L11_MeTrfase_PrmA.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR11006. PTHR11006. 1 hit.
PfamiPF06325. PrmA. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51678. SAM_MT_PRMT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8WUV3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
SDCEPARALR RSRRSAKFPE PRSRRGFALV LALVPGVGGR CARSLPNPVP
60 70 80 90 100
APRHAGLSGH HSHVLVSVRR YRLFTSAEET FSHCKSEHQF NIDSMVHKHG
110 120 130 140 150
LEFYGYIKLI NFIRLKNPTV EYMNSIYNPV PWEKEEYLKP VLEDDLLLQF
160 170 180 190 200
DVEDLYEPVS VPFSYPNGLS ENTSVVEKLK HMEARALSAE AALARAREDL
210 220 230 240 250
QKMKQFAQDF VMHTDVRTCS SSTSVIADLQ EDEDGVYFSS YGHYGIHEEM
260 270 280 290 300
LKDKIRTESY RDFIYQNPHI FKDKVVLDVG CGTGILSMFA AKAGAKKVLG
310 320 330 340 350
VDQSEILYQA MDIIRLNKLE DTITLIKGKI EEVHLPVEKV DVIISEWMGY
360 370 380 390 400
FLLFESMLDS VLYAKNKYLA KGGSVYPDIC TISLVAVSDV NKHADRIAFW
410 420 430 440 450
DDVYGFKMSC MKKAVIPEAV VEVLDPKTLI SEPCGIKHID CHTTSISDLE
460 470 480 490 500
FSSDFTLKIT RTSMCTAIAG YFDIYFEKNC HNRVVFSTGP QSTKTHWKQT
510 520 530 540
VFLLEKPFSV KAGEALKGKV TVHKNKKDPR SLTVTLTLNN STQTYGLQ
Length:548
Mass (Da):61,967
Last modified:March 1, 2002 - v1
Checksum:i11F5A3F52B105F56
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019339 mRNA. Translation: AAH19339.1.
RefSeqiNP_001138638.1. NM_001145166.1.
NP_001138639.1. NM_001145167.1.
UniGeneiHs.152337.

Genome annotation databases

GeneIDi10196.
KEGGihsa:10196.
UCSCiuc001mqc.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019339 mRNA. Translation: AAH19339.1.
RefSeqiNP_001138638.1. NM_001145166.1.
NP_001138639.1. NM_001145167.1.
UniGeneiHs.152337.

3D structure databases

ProteinModelPortaliQ8WUV3.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiQ8WUV3.

Proteomic databases

PRIDEiQ8WUV3.

Protocols and materials databases

DNASUi10196.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10196.
KEGGihsa:10196.
UCSCiuc001mqc.3. human.

Organism-specific databases

CTDi10196.
PharmGKBiPA29462.

Phylogenomic databases

HOGENOMiHOG000198521.
HOVERGENiHBG001793.
KOiK11436.

Miscellaneous databases

ChiTaRSiPRMT3. human.
GenomeRNAii10196.
NextBioi38588.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR025799. Arg_MeTrfase.
IPR010456. Ribosomal-L11_MeTrfase_PrmA.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR11006. PTHR11006. 1 hit.
PfamiPF06325. PrmA. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51678. SAM_MT_PRMT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: MuscleImported.

Entry informationi

Entry nameiQ8WUV3_HUMAN
AccessioniPrimary (citable) accession number: Q8WUV3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: January 7, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.