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Q8WUV3

- Q8WUV3_HUMAN

UniProt

Q8WUV3 - Q8WUV3_HUMAN

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Protein
Submitted name:

PRMT3 protein

Gene

PRMT3

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein methyltransferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PRMT3 proteinImported
Gene namesi
Name:PRMT3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29462.

PTM / Processingi

Proteomic databases

PRIDEiQ8WUV3.

Structurei

3D structure databases

ProteinModelPortaliQ8WUV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000198521.
HOVERGENiHBG001793.
KOiK11436.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR025799. Arg_MeTrfase.
IPR010456. Ribosomal-L11_MeTrfase_PrmA.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PANTHERiPTHR11006. PTHR11006. 1 hit.
PfamiPF06325. PrmA. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51678. SAM_MT_PRMT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8WUV3-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
SDCEPARALR RSRRSAKFPE PRSRRGFALV LALVPGVGGR CARSLPNPVP
60 70 80 90 100
APRHAGLSGH HSHVLVSVRR YRLFTSAEET FSHCKSEHQF NIDSMVHKHG
110 120 130 140 150
LEFYGYIKLI NFIRLKNPTV EYMNSIYNPV PWEKEEYLKP VLEDDLLLQF
160 170 180 190 200
DVEDLYEPVS VPFSYPNGLS ENTSVVEKLK HMEARALSAE AALARAREDL
210 220 230 240 250
QKMKQFAQDF VMHTDVRTCS SSTSVIADLQ EDEDGVYFSS YGHYGIHEEM
260 270 280 290 300
LKDKIRTESY RDFIYQNPHI FKDKVVLDVG CGTGILSMFA AKAGAKKVLG
310 320 330 340 350
VDQSEILYQA MDIIRLNKLE DTITLIKGKI EEVHLPVEKV DVIISEWMGY
360 370 380 390 400
FLLFESMLDS VLYAKNKYLA KGGSVYPDIC TISLVAVSDV NKHADRIAFW
410 420 430 440 450
DDVYGFKMSC MKKAVIPEAV VEVLDPKTLI SEPCGIKHID CHTTSISDLE
460 470 480 490 500
FSSDFTLKIT RTSMCTAIAG YFDIYFEKNC HNRVVFSTGP QSTKTHWKQT
510 520 530 540
VFLLEKPFSV KAGEALKGKV TVHKNKKDPR SLTVTLTLNN STQTYGLQ
Length:548
Mass (Da):61,967
Last modified:March 1, 2002 - v1
Checksum:i11F5A3F52B105F56
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC019339 mRNA. Translation: AAH19339.1.
RefSeqiNP_001138638.1. NM_001145166.1.
NP_001138639.1. NM_001145167.1.
UniGeneiHs.152337.

Genome annotation databases

GeneIDi10196.
KEGGihsa:10196.
UCSCiuc001mqc.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC019339 mRNA. Translation: AAH19339.1 .
RefSeqi NP_001138638.1. NM_001145166.1.
NP_001138639.1. NM_001145167.1.
UniGenei Hs.152337.

3D structure databases

ProteinModelPortali Q8WUV3.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q8WUV3.

Protocols and materials databases

DNASUi 10196.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 10196.
KEGGi hsa:10196.
UCSCi uc001mqc.3. human.

Organism-specific databases

CTDi 10196.
PharmGKBi PA29462.

Phylogenomic databases

HOGENOMi HOG000198521.
HOVERGENi HBG001793.
KOi K11436.

Miscellaneous databases

GenomeRNAii 10196.
NextBioi 38588.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
InterProi IPR025799. Arg_MeTrfase.
IPR010456. Ribosomal-L11_MeTrfase_PrmA.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
PANTHERi PTHR11006. PTHR11006. 1 hit.
Pfami PF06325. PrmA. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS51678. SAM_MT_PRMT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: MuscleImported.

Entry informationi

Entry nameiQ8WUV3_HUMAN
AccessioniPrimary (citable) accession number: Q8WUV3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.