ID   Q8WUT1_HUMAN            Unreviewed;       229 AA.
AC   Q8WUT1;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   24-JAN-2024, entry version 127.
DE   SubName: Full=POLDIP3 protein {ECO:0000313|EMBL:AAH19643.1};
GN   Name=POLDIP3 {ECO:0000313|EMBL:AAH19643.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAH19643.1};
RN   [1] {ECO:0000313|EMBL:AAH19643.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain {ECO:0000313|EMBL:AAH19643.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA   Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA   Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA   Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA   Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA   Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA   Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA   Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA   Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA   Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA   Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA   Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA   Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA   Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA   Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA   Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA   Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2] {ECO:0007829|PubMed:17924679}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17924679; DOI=10.1021/pr070152u;
RA   Yu L.R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
RT   "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells
RT   and high confident phosphopeptide identification by cross-validation of
RT   MS/MS and MS/MS/MS spectra.";
RL   J. Proteome Res. 6:4150-4162(2007).
RN   [3] {ECO:0007829|PubMed:17525332}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17525332; DOI=10.1126/science.1140321;
RA   Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R., Hurov K.E.,
RA   Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y.,
RA   Gygi S.P., Elledge S.J.;
RT   "ATM and ATR substrate analysis reveals extensive protein networks
RT   responsive to DNA damage.";
RL   Science 316:1160-1166(2007).
RN   [4] {ECO:0007829|PubMed:18669648}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA   Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA   Elledge S.J., Gygi S.P.;
RT   "A quantitative atlas of mitotic phosphorylation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN   [5] {ECO:0007829|PubMed:19690332}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19690332; DOI=10.1126/scisignal.2000007;
RA   Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K.,
RA   Rodionov V., Han D.K.;
RT   "Quantitative phosphoproteomic analysis of T cell receptor signaling
RT   reveals system-wide modulation of protein-protein interactions.";
RL   Sci. Signal. 2:RA46-RA46(2009).
RN   [6] {ECO:0007829|PubMed:20068231}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=20068231; DOI=10.1126/scisignal.2000475;
RA   Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L.,
RA   Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.;
RT   "Quantitative phosphoproteomics reveals widespread full phosphorylation
RT   site occupancy during mitosis.";
RL   Sci. Signal. 3:RA3-RA3(2010).
RN   [7] {ECO:0007829|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T.,
RA   Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [8] {ECO:0007829|PubMed:22223895}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22223895; DOI=10.1074/mcp.M111.015131;
RA   Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA   Giglione C.;
RT   "Comparative large-scale characterisation of plant vs. mammal proteins
RT   reveals similar and idiosyncratic N-alpha acetylation features.";
RL   Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
RN   [9] {ECO:0007829|PubMed:22814378}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA   Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA   Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA   Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT   "N-terminal acetylome analyses and functional insights of the N-terminal
RT   acetyltransferase NatB.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN   [10] {ECO:0007829|PubMed:23186163}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=23186163;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
RN   [11] {ECO:0007829|PubMed:24129315}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24129315;
RA   Guo A., Gu H., Zhou J., Mulhern D., Wang Y., Lee K.A., Yang V., Aguiar M.,
RA   Kornhauser J., Jia X., Ren J., Beausoleil S.A., Silva J.C., Vemulapalli V.,
RA   Bedford M.T., Comb M.J.;
RT   "Immunoaffinity enrichment and mass spectrometry analysis of protein
RT   methylation.";
RL   Mol. Cell. Proteomics 13:372-387(2014).
RN   [12] {ECO:0007829|PubMed:28112733}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=28112733;
RA   Hendriks I.A., Lyon D., Young C., Jensen L.J., Vertegaal A.C.,
RA   Nielsen M.L.;
RT   "Site-specific mapping of the human SUMO proteome reveals co-modification
RT   with phosphorylation.";
RL   Nat. Struct. Mol. Biol. 24:325-336(2017).
CC   -!- INTERACTION:
CC       Q8WUT1; Q8N9N5: BANP; NbExp=3; IntAct=EBI-10276663, EBI-744695;
CC       Q8WUT1; Q8TD16-2: BICD2; NbExp=3; IntAct=EBI-10276663, EBI-11975051;
CC       Q8WUT1; O95273: CCNDBP1; NbExp=3; IntAct=EBI-10276663, EBI-748961;
CC       Q8WUT1; Q96B26: EXOSC8; NbExp=3; IntAct=EBI-10276663, EBI-371922;
CC       Q8WUT1; Q08379: GOLGA2; NbExp=3; IntAct=EBI-10276663, EBI-618309;
CC       Q8WUT1; Q969Y2: GTPBP3; NbExp=3; IntAct=EBI-10276663, EBI-740290;
CC       Q8WUT1; Q6NT76: HMBOX1; NbExp=3; IntAct=EBI-10276663, EBI-2549423;
CC       Q8WUT1; O75031: HSF2BP; NbExp=3; IntAct=EBI-10276663, EBI-7116203;
CC       Q8WUT1; Q15323: KRT31; NbExp=3; IntAct=EBI-10276663, EBI-948001;
CC       Q8WUT1; Q6A162: KRT40; NbExp=3; IntAct=EBI-10276663, EBI-10171697;
CC       Q8WUT1; Q9BRK4: LZTS2; NbExp=6; IntAct=EBI-10276663, EBI-741037;
CC       Q8WUT1; Q9UJV3-2: MID2; NbExp=3; IntAct=EBI-10276663, EBI-10172526;
CC       Q8WUT1; Q5JR59: MTUS2; NbExp=3; IntAct=EBI-10276663, EBI-742948;
CC       Q8WUT1; Q5JR59-3: MTUS2; NbExp=3; IntAct=EBI-10276663, EBI-11522433;
CC       Q8WUT1; Q9UJX0: OSGIN1; NbExp=3; IntAct=EBI-10276663, EBI-9057006;
CC       Q8WUT1; P32243-2: OTX2; NbExp=3; IntAct=EBI-10276663, EBI-9087860;
CC       Q8WUT1; Q4G0R1: PIBF1; NbExp=3; IntAct=EBI-10276663, EBI-14066006;
CC       Q8WUT1; Q8ND90: PNMA1; NbExp=3; IntAct=EBI-10276663, EBI-302345;
CC       Q8WUT1; O15160: POLR1C; NbExp=3; IntAct=EBI-10276663, EBI-1055079;
CC       Q8WUT1; O75771: RAD51D; NbExp=3; IntAct=EBI-10276663, EBI-1055693;
CC       Q8WUT1; P0C264: SBK3; NbExp=3; IntAct=EBI-10276663, EBI-17181801;
CC       Q8WUT1; Q8WW24: TEKT4; NbExp=3; IntAct=EBI-10276663, EBI-750487;
CC       Q8WUT1; Q9UGI0: ZRANB1; NbExp=3; IntAct=EBI-10276663, EBI-527853;
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DR   EMBL; BC019643; AAH19643.1; -; mRNA.
DR   AlphaFoldDB; Q8WUT1; -.
DR   SMR; Q8WUT1; -.
DR   IntAct; Q8WUT1; 22.
DR   MassIVE; Q8WUT1; -.
DR   MaxQB; Q8WUT1; -.
DR   PeptideAtlas; Q8WUT1; -.
DR   Antibodypedia; 13265; 285 antibodies from 30 providers.
DR   UCSC; uc062ewa.1; human.
DR   VEuPathDB; HostDB:ENSG00000100227; -.
DR   ChiTaRS; POLDIP3; human.
DR   Bgee; ENSG00000100227; Expressed in ventricular zone and 215 other cell types or tissues.
DR   ExpressionAtlas; Q8WUT1; baseline and differential.
PE   1: Evidence at protein level;
SQ   SEQUENCE   229 AA;  24840 MW;  9150B20A3443C779 CRC64;
     MADISLDELI RKRGAAAKGR LNARPGVGGV RSRVGIQQGL LSQSTRTATF QQRFDARQKI
     GLSDARLKLG VKDAREKLLQ KDARFRIKGK VQDAREMLNS RKQQTTVPQK PRQVADAREK
     ISLKRSSPAA FINPPIGTVT PALKLTKTIQ NLYDLDEDDD GIASVPTKQM KFAASGGFLH
     HMAGLSSSKL SMSKALPLTK VVQNDAYTAP ALPSSIRTKA LPVLTSPGT
//