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Protein

Transmembrane protein 263

Gene

TMEM263

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Protein family/group databases

TCDBi8.A.101.1.1 the tmem263 (tmem263) family

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 263
Gene namesi
Name:TMEM263
Synonyms:C12orf23
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000151135.9
HGNCiHGNC:28281 TMEM263
neXtProtiNX_Q8WUH6

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000151135
PharmGKBiPA142672295

Polymorphism and mutation databases

BioMutaiC12orf23
DMDMi74730713

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002636291 – 116Transmembrane protein 263Add BLAST116

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi2N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiQ8WUH6
MaxQBiQ8WUH6
PaxDbiQ8WUH6
PeptideAtlasiQ8WUH6
PRIDEiQ8WUH6
TopDownProteomicsiQ8WUH6

PTM databases

iPTMnetiQ8WUH6
PhosphoSitePlusiQ8WUH6
SwissPalmiQ8WUH6

Expressioni

Gene expression databases

BgeeiENSG00000151135
CleanExiHS_C12orf23
ExpressionAtlasiQ8WUH6 baseline and differential
GenevisibleiQ8WUH6 HS

Organism-specific databases

HPAiHPA042339

Interactioni

Protein-protein interaction databases

BioGridi124723, 17 interactors
IntActiQ8WUH6, 18 interactors

Structurei

3D structure databases

ProteinModelPortaliQ8WUH6
SMRiQ8WUH6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM263 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IXK4 Eukaryota
ENOG4111SH7 LUCA
GeneTreeiENSGT00390000013899
HOGENOMiHOG000060332
HOVERGENiHBG058969
InParanoidiQ8WUH6
OMAiKNQQDIP
OrthoDBiEOG091G161H
PhylomeDBiQ8WUH6
TreeFamiTF333298

Family and domain databases

InterProiView protein in InterPro
IPR028153 UPF0444
PANTHERiPTHR31443 PTHR31443, 1 hit
PfamiView protein in Pfam
PF15475 UPF0444, 1 hit

Sequencei

Sequence statusi: Complete.

Q8WUH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQTDKNQQE IPSYLNDEPP EGSMKDHPQQ QPGMLSRVTG GIFSVTKGAV
60 70 80 90 100
GATIGGVAWI GGKSLEVTKT AVTTVPSMGI GLVKGGVSAV AGGVTAVGSA
110
VVNKVPLTGK KKDKSD
Length:116
Mass (Da):11,748
Last modified:March 1, 2002 - v1
Checksum:iA40412A1683989FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK021783 mRNA Translation: BAG51051.1
AK022770 mRNA Translation: BAG51112.1
AK024021 mRNA Translation: BAG51252.1
CH471054 Genomic DNA Translation: EAW97790.1
BC020522 mRNA Translation: AAH20522.1
CCDSiCCDS9110.1
RefSeqiNP_001306590.1, NM_001319661.1
NP_001306591.1, NM_001319662.1
NP_001306592.1, NM_001319663.1
NP_001306593.1, NM_001319664.1
NP_001306595.1, NM_001319666.1
NP_689474.1, NM_152261.3
UniGeneiHs.257664

Genome annotation databases

EnsembliENST00000280756; ENSP00000280756; ENSG00000151135
ENST00000547081; ENSP00000449106; ENSG00000151135
ENST00000547242; ENSP00000446537; ENSG00000151135
ENST00000548125; ENSP00000449785; ENSG00000151135
ENST00000550344; ENSP00000446717; ENSG00000151135
ENST00000551813; ENSP00000450350; ENSG00000151135
GeneIDi90488
KEGGihsa:90488
UCSCiuc001tmb.4 human

Similar proteinsi

Entry informationi

Entry nameiTM263_HUMAN
AccessioniPrimary (citable) accession number: Q8WUH6
Secondary accession number(s): B3KMN9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: March 1, 2002
Last modified: April 25, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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