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Q8WUF5

- IASPP_HUMAN

UniProt

Q8WUF5 - IASPP_HUMAN

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Protein

RelA-associated inhibitor

Gene

PPP1R13L

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.4 Publications

GO - Molecular functioni

  1. identical protein binding Source: IntAct
  2. transcription corepressor activity Source: ProtInc
  3. transcription factor binding Source: ProtInc

GO - Biological processi

  1. apoptotic process Source: UniProtKB-KW
  2. cardiac muscle contraction Source: Ensembl
  3. cardiac right ventricle morphogenesis Source: Ensembl
  4. embryonic camera-type eye development Source: Ensembl
  5. hair cycle Source: Ensembl
  6. multicellular organismal homeostasis Source: Ensembl
  7. multicellular organism growth Source: Ensembl
  8. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  9. post-embryonic development Source: Ensembl
  10. transcription, DNA-templated Source: UniProtKB-KW
  11. ventricular cardiac muscle tissue development Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Apoptosis, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RelA-associated inhibitor
Alternative name(s):
Inhibitor of ASPP protein
Short name:
Protein iASPP
NFkB-interacting protein 1
PPP1R13B-like protein
Gene namesi
Name:PPP1R13L
Synonyms:IASPP, NKIP1, PPP1R13BL, RAI
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:18838. PPP1R13L.

Subcellular locationi

Cytoplasm. Nucleus
Note: Predominantly cytoplasmic but also nuclear.

GO - Cellular componenti

  1. cell junction Source: HPA
  2. cytoplasm Source: HPA
  3. nucleus Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34195.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 828828RelA-associated inhibitorPRO_0000066966Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine1 Publication
Modified residuei102 – 1021Phosphoserine1 Publication
Modified residuei110 – 1101Phosphoserine3 Publications
Modified residuei113 – 1131Phosphoserine3 Publications
Modified residuei119 – 1191Phosphoserine1 Publication
Modified residuei120 – 1201Phosphoserine1 Publication
Modified residuei123 – 1231Phosphothreonine1 Publication
Modified residuei134 – 1341Phosphoserine1 Publication
Modified residuei183 – 1831Phosphoserine3 Publications
Modified residuei187 – 1871Phosphoserine3 Publications
Modified residuei203 – 2031Phosphoserine1 Publication
Modified residuei280 – 2801Phosphoserine1 Publication
Modified residuei316 – 3161Phosphoserine1 Publication
Modified residuei332 – 3321Phosphoserine1 Publication
Modified residuei526 – 5261Phosphoserine1 Publication
Modified residuei567 – 5671Phosphoserine4 Publications
Modified residuei597 – 5971Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ8WUF5.
PaxDbiQ8WUF5.
PRIDEiQ8WUF5.

PTM databases

PhosphoSiteiQ8WUF5.

Miscellaneous databases

PMAP-CutDBQ8WUF5.

Expressioni

Tissue specificityi

Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte.1 Publication

Gene expression databases

BgeeiQ8WUF5.
CleanExiHS_PPP1R13L.
ExpressionAtlasiQ8WUF5. baseline and differential.
GenevestigatoriQ8WUF5.

Organism-specific databases

HPAiCAB005016.
HPA041231.

Interactioni

Subunit structurei

Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.5 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
itself4EBI-5550163,EBI-5550163
Q9WMX22EBI-5550163,EBI-6863748From a different organism.
EP300Q094722EBI-5550163,EBI-447295
PPP1CAP621364EBI-5550163,EBI-357253
TP53P0463711EBI-5550163,EBI-366083

Protein-protein interaction databases

BioGridi116059. 11 interactions.
DIPiDIP-29586N.
IntActiQ8WUF5. 8 interactions.
MINTiMINT-7034564.
STRINGi9606.ENSP00000354218.

Structurei

Secondary structure

1
828
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi627 – 63711
Helixi640 – 64910
Helixi663 – 6697
Helixi673 – 6819
Helixi696 – 7027
Helixi706 – 7138
Turni714 – 7163
Helixi731 – 7333
Helixi741 – 75414
Turni755 – 7573
Helixi759 – 7613
Beta strandi762 – 7676
Beta strandi784 – 7918
Beta strandi796 – 8038
Beta strandi806 – 8116
Helixi812 – 8143
Beta strandi815 – 8184

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2VGEX-ray2.10A607-828[»]
ProteinModelPortaliQ8WUF5.
SMRiQ8WUF5. Positions 616-822.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8WUF5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati659 – 69133ANK 1Add
BLAST
Repeati692 – 72433ANK 2Add
BLAST
Domaini758 – 82063SH3PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi54 – 602549Pro-richAdd
BLAST
Compositional biasi407 – 44438Gln-richAdd
BLAST

Domaini

Isoform 1 N-terminal region is required for cytoplasmic localization.

Sequence similaritiesi

Belongs to the ASPP family.Curated
Contains 2 ANK repeats.PROSITE-ProRule annotation
Contains 1 SH3 domain.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat, SH3 domain

Phylogenomic databases

eggNOGiNOG237939.
GeneTreeiENSGT00760000119141.
HOVERGENiHBG055210.
InParanoidiQ8WUF5.
OMAiYEKKSSQ.
OrthoDBiEOG7WDN20.
PhylomeDBiQ8WUF5.
TreeFamiTF105545.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR028320. iASPP.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR24164. PTHR24164. 1 hit.
PfamiPF12796. Ank_2. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00248. ANK. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF50044. SSF50044. 2 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8WUF5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSEAFQSAR DFLDMNFQSL AMKHMDLKQM ELDTAAAKVD ELTKQLESLW
60 70 80 90 100
SDSPAPPGPQ AGPPSRPPRY SSSSIPEPFG SRGSPRKAAT DGADTPFGRS
110 120 130 140 150
ESAPTLHPYS PLSPKGRPSS PRTPLYLQPD AYGSLDRATS PRPRAFDGAG
160 170 180 190 200
SSLGRAPSPR PGPGPLRQQG PPTPFDFLGR AGSPRGSPLA EGPQAFFPER
210 220 230 240 250
GPSPRPPATA YDAPASAFGS SLLGSGGSAF APPLRAQDDL TLRRRPPKAW
260 270 280 290 300
NESDLDVAYE KKPSQTASYE RLDVFARPAS PSLQLLPWRE SSLDGLGGTG
310 320 330 340 350
KDNLTSATLP RNYKVSPLAS DRRSDAGSYR RSLGSAGPSG TLPRSWQPVS
360 370 380 390 400
RIPMPPSSPQ PRGAPRQRPI PLSMIFKLQN AFWEHGASRA MLPGSPLFTR
410 420 430 440 450
APPPKLQPQP QPQPQPQSQP QPQLPPQPQT QPQTPTPAPQ HPQQTWPPVN
460 470 480 490 500
EGPPKPPTEL EPEPEIEGLL TPVLEAGDVD EGPVARPLSP TRLQPALPPE
510 520 530 540 550
AQSVPELEEV ARVLAEIPRP LKRRGSMEQA PAVALPPTHK KQYQQIISRL
560 570 580 590 600
FHRHGGPGPG GPEPELSPIT EGSEARAGPP APAPPAPIPP PAPSQSSPPE
610 620 630 640 650
QPQSMEMRSV LRKAGSPRKA RRARLNPLVL LLDAALTGEL EVVQQAVKEM
660 670 680 690 700
NDPSQPNEEG ITALHNAICG ANYSIVDFLI TAGANVNSPD SHGWTPLHCA
710 720 730 740 750
ASCNDTVICM ALVQHGAAIF ATTLSDGATA FEKCDPYREG YADCATYLAD
760 770 780 790 800
VEQSMGLMNS GAVYALWDYS AEFGDELSFR EGESVTVLRR DGPEETDWWW
810 820
AALHGQEGYV PRNYFGLFPR VKPQRSKV
Length:828
Mass (Da):89,091
Last modified:April 4, 2006 - v4
Checksum:i7BEEF239B7CA9C70
GO

Sequence cautioni

The sequence AAD27005.1 differs from that shown. Reason: Probable cloning artifact.
The sequence AAD27004.1 differs from that shown. Reason: Frameshift at positions 439, 483, 562 and 591.
The sequence AAD27005.1 differs from that shown. Reason: Frameshift at positions 483, 562 and 591.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti198 – 1981P → S in AAH64913. (PubMed:15489334)Curated
Sequence conflicti223 – 2231L → I in AAW51146. 1 PublicationCurated
Sequence conflicti317 – 3182PL → AA in AAD27004. (PubMed:10336463)Curated
Sequence conflicti321 – 3211D → T in AAD27004. (PubMed:10336463)Curated
Sequence conflicti369 – 3691P → S in AAW51146. 1 PublicationCurated
Sequence conflicti372 – 3721Missing in AAW51146. 1 PublicationCurated
Sequence conflicti426 – 4261P → Q in AAD27004. (PubMed:10336463)Curated
Sequence conflicti439 – 4402PQ → HP in AAD27004. (PubMed:10336463)Curated
Sequence conflicti747 – 7471Y → S in AAW51146. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ888472 mRNA. Translation: CAI60219.1.
AY869712 mRNA. Translation: AAW51146.1.
DQ314886 Genomic DNA. Translation: ABC40745.1.
BC001475 mRNA. Translation: AAH01475.1.
BC020589 mRNA. Translation: AAH20589.1.
BC032298 mRNA. Translation: AAH32298.1.
BC064913 mRNA. Translation: AAH64913.1.
AF078036 mRNA. Translation: AAD27004.1. Frameshift.
AF078037 mRNA. Translation: AAD27005.1. Sequence problems.
CCDSiCCDS33050.1.
RefSeqiNP_001135974.1. NM_001142502.1.
NP_006654.2. NM_006663.3.
UniGeneiHs.466937.

Genome annotation databases

EnsembliENST00000360957; ENSP00000354218; ENSG00000104881.
ENST00000418234; ENSP00000403902; ENSG00000104881.
GeneIDi10848.
KEGGihsa:10848.
UCSCiuc002pbn.3. human.

Polymorphism databases

DMDMi92090607.

Cross-referencesi

Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ888472 mRNA. Translation: CAI60219.1 .
AY869712 mRNA. Translation: AAW51146.1 .
DQ314886 Genomic DNA. Translation: ABC40745.1 .
BC001475 mRNA. Translation: AAH01475.1 .
BC020589 mRNA. Translation: AAH20589.1 .
BC032298 mRNA. Translation: AAH32298.1 .
BC064913 mRNA. Translation: AAH64913.1 .
AF078036 mRNA. Translation: AAD27004.1 . Frameshift.
AF078037 mRNA. Translation: AAD27005.1 . Sequence problems.
CCDSi CCDS33050.1.
RefSeqi NP_001135974.1. NM_001142502.1.
NP_006654.2. NM_006663.3.
UniGenei Hs.466937.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2VGE X-ray 2.10 A 607-828 [» ]
ProteinModelPortali Q8WUF5.
SMRi Q8WUF5. Positions 616-822.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 116059. 11 interactions.
DIPi DIP-29586N.
IntActi Q8WUF5. 8 interactions.
MINTi MINT-7034564.
STRINGi 9606.ENSP00000354218.

PTM databases

PhosphoSitei Q8WUF5.

Polymorphism databases

DMDMi 92090607.

Proteomic databases

MaxQBi Q8WUF5.
PaxDbi Q8WUF5.
PRIDEi Q8WUF5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000360957 ; ENSP00000354218 ; ENSG00000104881 .
ENST00000418234 ; ENSP00000403902 ; ENSG00000104881 .
GeneIDi 10848.
KEGGi hsa:10848.
UCSCi uc002pbn.3. human.

Organism-specific databases

CTDi 10848.
GeneCardsi GC19M045883.
HGNCi HGNC:18838. PPP1R13L.
HPAi CAB005016.
HPA041231.
MIMi 607463. gene.
neXtProti NX_Q8WUF5.
PharmGKBi PA34195.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG237939.
GeneTreei ENSGT00760000119141.
HOVERGENi HBG055210.
InParanoidi Q8WUF5.
OMAi YEKKSSQ.
OrthoDBi EOG7WDN20.
PhylomeDBi Q8WUF5.
TreeFami TF105545.

Miscellaneous databases

EvolutionaryTracei Q8WUF5.
GeneWikii PPP1R13L.
GenomeRNAii 10848.
NextBioi 41185.
PMAP-CutDB Q8WUF5.
PROi Q8WUF5.
SOURCEi Search...

Gene expression databases

Bgeei Q8WUF5.
CleanExi HS_PPP1R13L.
ExpressionAtlasi Q8WUF5. baseline and differential.
Genevestigatori Q8WUF5.

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR028320. iASPP.
IPR001452. SH3_domain.
[Graphical view ]
PANTHERi PTHR24164. PTHR24164. 1 hit.
Pfami PF12796. Ank_2. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00248. ANK. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
SSF50044. SSF50044. 2 hits.
PROSITEi PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization."
    Slee E.A., Gillotin S., Bergamaschi D., Royer C., Llanos S., Ali S., Jin B., Trigiante G., Lu X.
    Oncogene 23:9007-9016(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH TP53.
  2. Herron B.J., Rao C., Beier D.R.
    Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. NHLBI resequencing and genotyping service (RS&G)
    Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Liver, Placenta and Testis.
  5. "Identification of a novel inhibitor of nuclear factor-kappaB, RelA-associated inhibitor."
    Yang J.-P., Hori M., Sanda T., Okamoto T.
    J. Biol. Chem. 274:15662-15670(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 317-828, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INTERACTION WITH RELA.
    Tissue: Placenta.
  6. "RelA-associated inhibitor blocks transcription of human immunodeficiency virus type 1 by inhibiting NF-kappaB and Sp1 actions."
    Takada N., Sanda T., Okamoto H., Yang J.-P., Asamitsu K., Sarol L., Kimura G., Uranishi H., Tetsuka T., Okamoto T.
    J. Virol. 76:8019-8030(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH SP1.
  7. Cited for: FUNCTION, INTERACTION WITH TP53.
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-567, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
    Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
    Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-110; SER-113; SER-183 AND SER-187, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
    Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
    Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-567, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102; SER-110; SER-113; SER-119; SER-120; THR-123; SER-134; SER-203; SER-316; SER-332; SER-526; SER-567 AND SER-597, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  12. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-183 AND SER-187, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  13. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-110; SER-113; SER-183; SER-187; SER-280 AND SER-567, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  14. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  15. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  16. "Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73."
    Robinson R.A., Lu X., Jones E.Y., Siebold C.
    Structure 16:259-268(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 607-828, INTERACTION WITH TP53/P53; TP63 AND TP73.

Entry informationi

Entry nameiIASPP_HUMAN
AccessioniPrimary (citable) accession number: Q8WUF5
Secondary accession number(s): Q2PNZ9
, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: April 4, 2006
Last modified: October 29, 2014
This is version 121 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3