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Q8WUB2

- F216A_HUMAN

UniProt

Q8WUB2 - F216A_HUMAN

Protein

Protein FAM216A

Gene

FAM216A

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein FAM216A
    Gene namesi
    Name:FAM216A
    Synonyms:C12orf24
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Organism-specific databases

    HGNCiHGNC:30180. FAM216A.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA128395781.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 273273Protein FAM216APRO_0000288861Add
    BLAST

    Proteomic databases

    PaxDbiQ8WUB2.
    PRIDEiQ8WUB2.

    PTM databases

    PhosphoSiteiQ8WUB2.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8WUB2.
    BgeeiQ8WUB2.
    CleanExiHS_C12orf24.
    GenevestigatoriQ8WUB2.

    Organism-specific databases

    HPAiHPA038286.
    HPA038287.

    Interactioni

    Protein-protein interaction databases

    BioGridi118951. 1 interaction.
    STRINGi9606.ENSP00000366901.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8WUB2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the FAM216 family.Curated

    Phylogenomic databases

    eggNOGiNOG47451.
    HOGENOMiHOG000111755.
    HOVERGENiHBG102671.
    InParanoidiQ8WUB2.
    OMAiHYPCTTW.
    OrthoDBiEOG7DC257.
    PhylomeDBiQ8WUB2.
    TreeFamiTF337546.

    Family and domain databases

    InterProiIPR029373. FAM216.
    [Graphical view]
    PfamiPF15107. FAM216B. 1 hit.
    [Graphical view]
    ProtoNetiSearch...

    Sequencei

    Sequence statusi: Complete.

    Q8WUB2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLGQLLPHTA RGLGAAEMPG QGPGSDWTER SSSAEPPAVA GTEGGGGGSA    50
    GYSCYQNSKG SDRIKDGYKV NSHIAKLQEL WKTPQNQTIH LSKSMMEASF 100
    FKHPDLTTGQ KRYLCSIAKI YNANYLKMLM KRQYMHVLQH SSQKPGVLTH 150
    HRSRLSSRYS QKQHYPCTTW RHQLEREDSG SSDIAAASAP EMLIQHSLWR 200
    PVRNKEGIKT GYASKTRCKS LKIFRRPRKL FMQTVSSDDS ESHMSEEKKE 250
    EDLLNNFMQS MSIEEQGEHL MLT 273
    Length:273
    Mass (Da):30,792
    Last modified:March 1, 2002 - v1
    Checksum:iB06EF30057AB8586
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti225 – 2251R → G.
    Corresponds to variant rs17188964 [ dbSNP | Ensembl ].
    VAR_032513

    Sequence conflict

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti200 – 2001R → W in AAB50215. (PubMed:9110174)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U79274 mRNA. Translation: AAB50215.1.
    CR457001 mRNA. Translation: CAG33282.1.
    AC002350 Genomic DNA. No translation available.
    CH471054 Genomic DNA. Translation: EAW97917.1.
    BC020967 mRNA. Translation: AAH20967.1.
    CCDSiCCDS31899.1.
    RefSeqiNP_037432.2. NM_013300.2.
    UniGeneiHs.436618.

    Genome annotation databases

    EnsembliENST00000377673; ENSP00000366901; ENSG00000204856.
    GeneIDi29902.
    KEGGihsa:29902.
    UCSCiuc001tqu.4. human.

    Polymorphism databases

    DMDMi74730685.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U79274 mRNA. Translation: AAB50215.1 .
    CR457001 mRNA. Translation: CAG33282.1 .
    AC002350 Genomic DNA. No translation available.
    CH471054 Genomic DNA. Translation: EAW97917.1 .
    BC020967 mRNA. Translation: AAH20967.1 .
    CCDSi CCDS31899.1.
    RefSeqi NP_037432.2. NM_013300.2.
    UniGenei Hs.436618.

    3D structure databases

    ProteinModelPortali Q8WUB2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 118951. 1 interaction.
    STRINGi 9606.ENSP00000366901.

    PTM databases

    PhosphoSitei Q8WUB2.

    Polymorphism databases

    DMDMi 74730685.

    Proteomic databases

    PaxDbi Q8WUB2.
    PRIDEi Q8WUB2.

    Protocols and materials databases

    DNASUi 29902.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000377673 ; ENSP00000366901 ; ENSG00000204856 .
    GeneIDi 29902.
    KEGGi hsa:29902.
    UCSCi uc001tqu.4. human.

    Organism-specific databases

    CTDi 29902.
    GeneCardsi GC12P110907.
    HGNCi HGNC:30180. FAM216A.
    HPAi HPA038286.
    HPA038287.
    neXtProti NX_Q8WUB2.
    PharmGKBi PA128395781.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG47451.
    HOGENOMi HOG000111755.
    HOVERGENi HBG102671.
    InParanoidi Q8WUB2.
    OMAi HYPCTTW.
    OrthoDBi EOG7DC257.
    PhylomeDBi Q8WUB2.
    TreeFami TF337546.

    Miscellaneous databases

    GenomeRNAii 29902.
    NextBioi 52470.
    PROi Q8WUB2.

    Gene expression databases

    ArrayExpressi Q8WUB2.
    Bgeei Q8WUB2.
    CleanExi HS_C12orf24.
    Genevestigatori Q8WUB2.

    Family and domain databases

    InterProi IPR029373. FAM216.
    [Graphical view ]
    Pfami PF15107. FAM216B. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Large-scale concatenation cDNA sequencing."
      Yu W., Andersson B., Worley K.C., Muzny D.M., Ding Y., Liu W., Ricafrente J.Y., Wentland M.A., Lennon G., Gibbs R.A.
      Genome Res. 7:353-358(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.
    2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    3. "The finished DNA sequence of human chromosome 12."
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Colon.

    Entry informationi

    Entry nameiF216A_HUMAN
    AccessioniPrimary (citable) accession number: Q8WUB2
    Secondary accession number(s): A6NH30, Q99776
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    It is uncertain whether Met-1 or Met-18 is the initiator.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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