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Q8WTZ3 (YS049_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger protein ENSP00000375192
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus Probable.

Sequence similarities

Contains 1 C2H2-type zinc finger.

Caution

Was initially described as ZNF99.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainZinc-finger
   LigandDNA-binding
Metal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 238238Zinc finger protein ENSP00000375192
PRO_0000277871

Regions

Zinc finger27 – 4923C2H2-type; degenerate

Sequences

Sequence LengthMass (Da)Tools
Q8WTZ3 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: FACFD0DB5B6E1C1F

FASTA23827,158
        10         20         30         40         50         60 
MKNVANTVTI SHILPHIKII HTEEKPDKCE ECNKVFNWSS THTKYKRIHT EDKFYKYEEC 

        70         80         90        100        110        120 
DKSFKNISTL ITHKIIYVVE KFYKCEECGK VFFFFLKWSL TLSPKLECNG AISVHCNLRL 

       130        140        150        160        170        180 
LGSSDSLAST SQAAGIAGAC HHAQLIFVFL VETGFHHFDQ AGFELLTSSD PPALASQSAP 

       190        200        210        220        230 
KCWDYKHEPL SPVECGKVFN KLSNHTGEKL YKPKRHDSAL ENTLNFSKHK RNHSVKKP 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC021822 mRNA. Translation: AAH21822.1.
UniGeneHs.568380.
Hs.737077.

3D structure databases

ProteinModelPortalQ8WTZ3.
SMRQ8WTZ3. Positions 24-92, 180-238.
ModBaseSearch...
MobiDBSearch...

Polymorphism databases

DMDM74762627.

Proteomic databases

PRIDEQ8WTZ3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

neXtProtNX_Q8WTZ3.

Phylogenomic databases

PhylomeDBQ8WTZ3.

Gene expression databases

BgeeQ8WTZ3.
GenevestigatorQ8WTZ3.

Family and domain databases

Gene3D3.30.160.60. 2 hits.
InterProIPR007087. Znf_C2H2.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PROSITEPS50157. ZINC_FINGER_C2H2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYS049_HUMAN
AccessionPrimary (citable) accession number: Q8WTZ3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: March 1, 2002
Last modified: June 11, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 19

Human chromosome 19: entries, gene names and cross-references to MIM