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Q8WTZ3

- YS049_HUMAN

UniProt

Q8WTZ3 - YS049_HUMAN

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Protein

Zinc finger protein ENSP00000375192

Gene
N/A
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri27 – 4923C2H2-type; degenerateAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein ENSP00000375192
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Subcellular locationi

Nucleus Inferred

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 238238Zinc finger protein ENSP00000375192PRO_0000277871Add
BLAST

Proteomic databases

PRIDEiQ8WTZ3.

Expressioni

Gene expression databases

BgeeiQ8WTZ3.
GenevestigatoriQ8WTZ3.

Structurei

3D structure databases

ProteinModelPortaliQ8WTZ3.
SMRiQ8WTZ3. Positions 24-92, 180-238.

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri27 – 4923C2H2-type; degenerateAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

PhylomeDBiQ8WTZ3.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR007087. Znf_C2H2.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PROSITEiPS50157. ZINC_FINGER_C2H2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8WTZ3-1 [UniParc]FASTAAdd to Basket

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MKNVANTVTI SHILPHIKII HTEEKPDKCE ECNKVFNWSS THTKYKRIHT    50
EDKFYKYEEC DKSFKNISTL ITHKIIYVVE KFYKCEECGK VFFFFLKWSL 100
TLSPKLECNG AISVHCNLRL LGSSDSLAST SQAAGIAGAC HHAQLIFVFL 150
VETGFHHFDQ AGFELLTSSD PPALASQSAP KCWDYKHEPL SPVECGKVFN 200
KLSNHTGEKL YKPKRHDSAL ENTLNFSKHK RNHSVKKP 238
Length:238
Mass (Da):27,158
Last modified:March 1, 2002 - v1
Checksum:iFACFD0DB5B6E1C1F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC021822 mRNA. Translation: AAH21822.1.
UniGeneiHs.568380.
Hs.737077.

Polymorphism databases

DMDMi74762627.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC021822 mRNA. Translation: AAH21822.1 .
UniGenei Hs.568380.
Hs.737077.

3D structure databases

ProteinModelPortali Q8WTZ3.
SMRi Q8WTZ3. Positions 24-92, 180-238.
ModBasei Search...
MobiDBi Search...

Polymorphism databases

DMDMi 74762627.

Proteomic databases

PRIDEi Q8WTZ3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

neXtProti NX_Q8WTZ3.

Phylogenomic databases

PhylomeDBi Q8WTZ3.

Gene expression databases

Bgeei Q8WTZ3.
Genevestigatori Q8WTZ3.

Family and domain databases

Gene3Di 3.30.160.60. 2 hits.
InterProi IPR007087. Znf_C2H2.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
PROSITEi PS50157. ZINC_FINGER_C2H2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiYS049_HUMAN
AccessioniPrimary (citable) accession number: Q8WTZ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: March 1, 2002
Last modified: June 11, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Was initially described as ZNF99.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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