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Q8WTZ3

- YS049_HUMAN

UniProt

Q8WTZ3 - YS049_HUMAN

Protein

Zinc finger protein ENSP00000375192

Gene
N/A
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri27 – 4923C2H2-type; degeneratePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Zinc finger protein ENSP00000375192
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Unplaced

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 238238Zinc finger protein ENSP00000375192PRO_0000277871Add
    BLAST

    Proteomic databases

    PRIDEiQ8WTZ3.

    Expressioni

    Gene expression databases

    BgeeiQ8WTZ3.
    GenevestigatoriQ8WTZ3.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8WTZ3.
    SMRiQ8WTZ3. Positions 24-92, 180-238.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 C2H2-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri27 – 4923C2H2-type; degeneratePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    PhylomeDBiQ8WTZ3.

    Family and domain databases

    Gene3Di3.30.160.60. 2 hits.
    InterProiIPR007087. Znf_C2H2.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PROSITEiPS50157. ZINC_FINGER_C2H2_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8WTZ3-1 [UniParc]FASTAAdd to Basket

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    MKNVANTVTI SHILPHIKII HTEEKPDKCE ECNKVFNWSS THTKYKRIHT    50
    EDKFYKYEEC DKSFKNISTL ITHKIIYVVE KFYKCEECGK VFFFFLKWSL 100
    TLSPKLECNG AISVHCNLRL LGSSDSLAST SQAAGIAGAC HHAQLIFVFL 150
    VETGFHHFDQ AGFELLTSSD PPALASQSAP KCWDYKHEPL SPVECGKVFN 200
    KLSNHTGEKL YKPKRHDSAL ENTLNFSKHK RNHSVKKP 238
    Length:238
    Mass (Da):27,158
    Last modified:March 1, 2002 - v1
    Checksum:iFACFD0DB5B6E1C1F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC021822 mRNA. Translation: AAH21822.1.
    UniGeneiHs.568380.
    Hs.737077.

    Polymorphism databases

    DMDMi74762627.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC021822 mRNA. Translation: AAH21822.1 .
    UniGenei Hs.568380.
    Hs.737077.

    3D structure databases

    ProteinModelPortali Q8WTZ3.
    SMRi Q8WTZ3. Positions 24-92, 180-238.
    ModBasei Search...
    MobiDBi Search...

    Polymorphism databases

    DMDMi 74762627.

    Proteomic databases

    PRIDEi Q8WTZ3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    neXtProti NX_Q8WTZ3.

    Phylogenomic databases

    PhylomeDBi Q8WTZ3.

    Gene expression databases

    Bgeei Q8WTZ3.
    Genevestigatori Q8WTZ3.

    Family and domain databases

    Gene3Di 3.30.160.60. 2 hits.
    InterProi IPR007087. Znf_C2H2.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    PROSITEi PS50157. ZINC_FINGER_C2H2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.

    Entry informationi

    Entry nameiYS049_HUMAN
    AccessioniPrimary (citable) accession number: Q8WTZ3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 20, 2007
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    Was initially described as ZNF99.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3