Q8WTQ6 (Q8WTQ6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nav1.5 EMBL CAC84533.1

Gene names

Name:

SCN5A EMBL CAC84533.1

Organism

Homo sapiens (Human) EMBL CAC84533.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	156 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	Transmembrane RuleBase RU003378
Molecular function	Ion channel RuleBase RU003378
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ion channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAC84533.1
	Non-terminal residue	156	1	EMBL CAC84533.1

Sequences

	Sequence		Length	Mass (Da)
	Q8WTQ6 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: C9EE433E3CB613D5	FASTA	156	17,544
	10 20 30 40 50 60 MAQHDPPPWT KYVEYTFTAI YTFESLVKIL ARGFCLHAFT FLRDPWNWLD FSVIIMAYTT 70 80 90 100 110 120 EFVDLGNVSA LRTFRVLRAL KTISVISGLK TIVGALIQSV KKLADVMVLT VFCLSVFALI 130 140 150 GLQLFMGNLR HKCVRNFTAL NGTNGSVEAD GLVWES

References

[1]

"Upregulation of voltage-gated Na+ channel expression and metastatic potential in human breast cancer: Correlative studies on cell lines and biopsy tissues." Diss J.K.J., Fraser S.P., Coombes R.C., Djamgoz M.B.A. Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Biopsy sample 1 EMBL CAC84533.1 and Biopsy sample 7 EMBL CAC84534.1. Tissue: Breast EMBL CAC84533.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ310890 mRNA. Translation: CAC84533.1. AJ310891 mRNA. Translation: CAC84534.1.
IPI	IPI00926465.
UniGene	Hs.517898.
3D structure databases
HSSP	HSSP built from PDB template 1QG9 based on UniProtKB P08104.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8WTQ6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q8WTQ6.
Bgee	Q8WTQ6.
Family and domain databases
InterPro	IPR005821. Ion_trans_dom. [Graphical view]
Pfam	PF00520. Ion_trans. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8WTQ6_HUMAN

Accession

Primary (citable) accession number: Q8WTQ6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.