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Protein
Submitted name:

Soluble acetylcholine receptor

Gene
N/A
Organism
Aplysia californica (California sea hare)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei25MannoseCombined sources1
Metal bindingi42Magnesium 1Combined sources1
Binding sitei42Beta-D-mannose; via carbonyl oxygenCombined sources1
Binding sitei43MannoseCombined sources1
Metal bindingi88Magnesium 2Combined sources1
Binding sitei88Mannose; via carbonyl oxygenCombined sources1
Metal bindingi167Magnesium 3Combined sources1
Metal bindingi167Magnesium 4Combined sources1
Metal bindingi170Magnesium 4Combined sources1
Binding sitei179Beta-D-mannoseCombined sources1
Binding sitei197MannoseCombined sources1
Metal bindingi204Magnesium 2; via tele nitrogenCombined sources1
Binding sitei220Beta-D-mannoseCombined sources1

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported
LigandMagnesiumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Soluble acetylcholine receptorImported
OrganismiAplysia californica (California sea hare)Imported
Taxonomic identifieri6500 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaHeterobranchiaEuthyneuraEuopisthobranchiaAplysiomorphaAplysioideaAplysiidaeAplysia

Subcellular locationi

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1944497

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500431661420 – 236Sequence analysisAdd BLAST217

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi91N-linked (GlcNAc...)Combined sources1
Disulfide bondi144 ↔ 157Combined sources
Disulfide bondi207 ↔ 208Combined sources

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

DIPiDIP-46103N
IntActiQ8WSF8 2 interactors.
MINTiQ8WSF8

Chemistry databases

BindingDBiQ8WSF8

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BR7X-ray3.00A/B/C/D/E20-236[»]
2BR8X-ray2.40A/B/C/D/E20-236[»]
2BYNX-ray2.02A/B/C/D/E16-236[»]
2BYPX-ray2.07A/B/C/D/E18-225[»]
2BYQX-ray3.40A/B/C/D/E16-236[»]
2BYRX-ray2.45A/B/C/D/E/F/G/H/I/J18-236[»]
2BYSX-ray2.05A/B/C/D/E/F/G/H/I/J16-236[»]
2C9TX-ray2.25A/B/C/D/E/F/G/H/I/J20-236[»]
2PGZX-ray1.76A/B/C/D/E18-236[»]
2PH9X-ray2.88A/B/C/D/E18-236[»]
2UZ6X-ray2.40A/B/C/D/E/F/G/H/I/J20-236[»]
2W8FX-ray2.70A/B/C/D/E/F/G/H/I/J20-236[»]
2W8GX-ray2.60A/B/C/D/E20-236[»]
2WN9X-ray1.75A/B/C/D/E16-236[»]
2WNCX-ray2.20A/B/C/D/E16-236[»]
2WNJX-ray1.80A/B/C/D/E16-236[»]
2WNLX-ray2.70A/B/C/D/E/F/G/H/I/J16-236[»]
2WZYX-ray2.51A/B/C/D/E/F/G/H/I/J16-236[»]
2X00X-ray2.40A/B/C/E16-236[»]
D18-236[»]
2XNTX-ray3.21A/B/C/D/E/F/G/H/I/J1-236[»]
2XNUX-ray2.55A/B/C/D/E1-236[»]
2XNVX-ray2.44A/B/C/D/E/F/G/H/I/J1-236[»]
2XYSX-ray1.91A/B/C/D/E20-236[»]
2XYTX-ray2.05A/B/C/D/E/F/G/H/I/J20-236[»]
2XZ5X-ray2.80A/B/C/D/E20-236[»]
2XZ6X-ray3.14A/B/C/D/E/F/G/H/I/J20-236[»]
2Y54X-ray3.65A/B/C/D/E20-236[»]
2Y56X-ray3.59A/B/C/D/E20-236[»]
2Y57X-ray3.30A/B/C/D/E20-236[»]
2Y58X-ray3.25A/B/C/D/E20-236[»]
2Y7YX-ray1.90A/B/C/D/E20-236[»]
2YMDX-ray1.96A/B/C/D/E/F/G/H/I/J20-231[»]
2YMEX-ray2.40A/B/C/D/E/F/G/H/I/J20-224[»]
3C79X-ray2.48A/B/C/D/E18-236[»]
3C84X-ray1.94A/B/C/D/E18-236[»]
3GUAX-ray3.10A/B/C/D/E/F/G/H/I/J18-225[»]
3PEOX-ray2.10A/B/C/D/E/F/G/H/I/J18-236[»]
3PMZX-ray2.44A/B/C/D/E/F/G/H/I/J18-236[»]
3SH1X-ray2.90A/B/C/D/E/F/G/H/I/J18-236[»]
3SIOX-ray2.32A/B/C/D/E/F/G/H/I/J18-236[»]
3T4MX-ray3.00A/B/C/D/E/F/G/H/I/J18-236[»]
4AFTX-ray3.20A/B/C/D/E20-236[»]
4BFQX-ray2.40A/B/C/D/E20-236[»]
4BQTX-ray2.88A/B/C/D/E20-236[»]
4DBMX-ray2.30A/B/C/D/E18-236[»]
4EZ1X-ray2.49A/B/C/D/E18-236[»]
4FRRX-ray2.20A/B/C/D/E/F/G/H/I/J18-225[»]
4WV9X-ray2.00A/B/C/D/E18-224[»]
4XHEX-ray1.90A/B/C/D/E/F/G/H/I/J18-225[»]
4XK9X-ray2.20A/B/C/D/E/F/G/H/I/J18-236[»]
4ZJSX-ray2.23A/B/C/D/E50-77[»]
A/B/C/D/E99-236[»]
4ZK4X-ray1.90A/B/C/D/E18-71[»]
A/B/C/D/E73-198[»]
A/B/C/D/E215-236[»]
5AINX-ray2.30A/B/C/D/E20-231[»]
5BRXX-ray2.05A/B/C/D/E/F/G/H/I/J18-236[»]
5BW2X-ray2.27A/B/C/D/E18-236[»]
5CO5X-ray2.10A/B/D/G/I1-236[»]
5JMEX-ray2.34A/B/C/D/E18-236[»]
5KE4X-ray2.55A/B/C/D/E18-236[»]
5KZUX-ray2.30A/B/C/D/E18-236[»]
5LXBX-ray2.34A/B/C/D/E/F/G/H/I/J1-236[»]
5SYOX-ray2.00A/B/C/D/E18-71[»]
A/B/C/D/E73-198[»]
A/B/C/D/E215-236[»]
5TSFX-ray2.29A/B/C/D/E18-236[»]
5TVCX-ray1.93A/B/C/D/E18-71[»]
A/B/C/D/E73-198[»]
A/B/C/D/E215-236[»]
5TVHX-ray2.40A/B/C/D/E18-236[»]
ProteinModelPortaliQ8WSF8
SMRiQ8WSF8
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8WSF8

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 222Neur_chan_LBDInterPro annotationAdd BLAST188

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni153 – 156Mannose bindingCombined sources4

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.70.170.101 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
SUPFAMiSSF63712 SSF63712, 1 hit

Sequencei

Sequence statusi: Complete.

Q8WSF8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVSVYLALL VACVGQAHSQ ANLMRLKSDL FNRSPMYPGP TKDDPLTVTL
60 70 80 90 100
GFTLQDIVKA DSSTNEVDLV YYEQQRWKLN SLMWDPNEYG NITDFRTSAA
110 120 130 140 150
DIWTPDITAY SSTRPVQVLS PQIAVVTHDG SVMFIPAQRL SFMCDPTGVD
160 170 180 190 200
SEEGATCAVK FGSWVYSGFE IDLKTDTDQV DLSSYYASSK YEILSATQTR
210 220 230
QVQHYSCCPE PYIDVNLVVK FRERRAGNGF FRNLFD
Length:236
Mass (Da):26,568
Last modified:March 1, 2002 - v1
Checksum:i6D0DE487C46707BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF322877 mRNA Translation: AAL37251.1
RefSeqiNP_001191488.1, NM_001204559.1
UniGeneiAcl.89

Genome annotation databases

GeneIDi100533247

Entry informationi

Entry nameiQ8WSF8_APLCA
AccessioniPrimary (citable) accession number: Q8WSF8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: February 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources