Unreviewed, UniProtKB/TrEMBL Q8WQL7 (Q8WQL7_CAEEL)

Names and origin

Protein names

Submitted name:
    Protein T04C10.1, confirmed by transcript evidence EMBL CAA93756.2
Submitted name:
    Minibrain kinase EMBL AAL40874.1

Gene names

Name:	mbk-1 EMBL AAL40874.1 WormBase WBGene00003149 WormPep T04C10.1
ORF Names:	T04C10.1 WormPep T04C10.1

Organism

Caenorhabditis elegans [Complete proteome] EMBL AAL40874.1

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	882 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily. RuleBase RU000305V3

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304V2 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305V3 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	locomotion Inferred from mutant phenotype. Source: WormBase positive regulation of growth rate Inferred from mutant phenotype. Source: WormBase protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct protein serine/threonine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8WQL7-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: DD5C9DD354DA7098	FASTA	882	101,244
	10 20 30 40 50 60 MNTADVPDNL QSWGQQPSSS YSNTQQHSQM TNLPPINHNN LCDTEPMNED FQLQDVQADE 70 80 90 100 110 120 LQKQQKQQEQ QHIQQQNAQR FIAQSRQPHS NILRFPQPPI TSIKTNSHAF YPQQEVTQVR 130 140 150 160 170 180 PKKHRVSMTN AEAALTPGMP PEKQAAKKRN IGQFSTDTVP AGIGMIGIPF ESTSKPLQIQ 190 200 210 220 230 240 QFRNPQDAPV RKLTSDLIKT YKAINESFYL RKQVRRDRHK SQDAGKPKGS KDGSGASLTD 250 260 270 280 290 300 TFSIHNAIPI TSSDNHYQQD AHQNAPPLLD TNAPPTSTMV VPMRTETDLQ QQQRQKSSRG 310 320 330 340 350 360 GPYNNGYDDQ NYDYILKNGE IFDKRYVILS DTPVGKGSFG QVTKAYDTLN KEEVAIKIIK 370 380 390 400 410 420 NKKTFFDQAQ IEIHLLELTN AHDKDNKYNI VTLKGHFVHR AHLCLVFELL SYNLYDLLKN 430 440 450 460 470 480 TSFRGVSLNL ARKFAQQLGK TLLFLSSPEL SIIHCDLKPE NVLLVNAKRS QIRVIDFGSS 490 500 510 520 530 540 CQTGHRIYQY IQSRFYRSPE VLLGIAYDTK IDMWSLGCIL VEMHTGEPLF AGSSEVDQMM 550 560 570 580 590 600 KIVEVLGMPP KEMLDIGPKT HKYFDKTEDG IYYCKKTRDG YRHTYKAPGA RKLHEILGVT 610 620 630 640 650 660 SGGPGGRRLG EPGHSVEDYS KFKDLIKRML QFDPKQRISP YYVVRHPFLK QKEERVPSQP 670 680 690 700 710 720 PVSHSNLQQQ QQLYIQQPSS QMSQVMESPS VGSVYVEDNG MYRQAPGSSA NPISVTSSFD 730 740 750 760 770 780 EGDAMEVDAG RRRFSAHQQN YHNPNYQYSQ PQQQQQQQYQ QTQRTQLEQQ QKQAQLQQQL 790 800 810 820 830 840 QQQQMQQQQQ QQQQRQHMPQ AQSSSQQHLQ SRARPRQQDQ NEWRNQFELD DTFQQKQRKV 850 860 870 880 DDSVSNQISR NQFNPQQVSM THGNVNANNR EMEKLDYPNN KL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A." Raich W.B., Moorman C., Lacefield C.O., Lehrer J., Bartsch D., Plasterk R.H., Kandel E.R., Hobert O. Genetics 163:571-580(2003) [PubMed: 12618396] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY064464 mRNA. Translation: AAL40874.1. Z69885 Genomic DNA. Translation: CAA93756.2.
PIR	T24445.
RefSeq	NP_510460.2.
UniGene	Cel.22462
3D structure databases
HSSP	HSSP built from PDB template 1H0V based on UniProtKB P24941.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8WQL7. 1 interaction.
Genome annotation databases
Ensembl	T04C10.1. Caenorhabditis elegans. [Contig view]
GeneID	181578.
KEGG	cel:T04C10.1.
Organism-specific databases
WormBase	WBGene00003149. mbk-1.
WormPep	T04C10.1. CE33442. [WorfDB]
Phylogenomic databases
OMA	Q8WQL7. YKAINES.
Gene expression databases
ArrayExpress	Q8WQL7.
Family and domain databases
InterPro	IPR000719. Prot_kinase_core. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_pkinase-rel. IPR008271. Ser_thr_pkin_AS. IPR002290. Ser_thr_pkinase. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
ProDom	PD000001. Prot_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	914518.

Entry information

Entry name

Q8WQL7_CAEEL

Accession

Primary (citable) accession number: Q8WQL7
Secondary accession number(s): Q22155

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 5, 2009
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)