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Protein
Submitted name:

AGAP009190-PA

Gene

GSTe8

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP009190-PAImported
Submitted name:
Glutathione S-transferase e8Imported
Gene namesi
Name:GSTe8Imported
Synonyms:GSTU4Imported
ORF Names:AgaP_AGAP009190Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
ProteomesiUP000007062 Componenti: Chromosome 3R

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP009190-PA.

Structurei

3D structure databases

ProteinModelPortaliQ8WQJ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GST superfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0625.
HOGENOMiHOG000125741.
InParanoidiQ8WQJ5.
KOiK00799.
OMAiFFECSFL.
OrthoDBiEOG70089Q.
PhylomeDBiQ8WQJ5.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8WQJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILYYDEVSP PVRGVLLAIA ALGVKDRIKL EYIDLFKGGH LSSDYLKINP
60 70 80 90 100
LHTVPVLRHG ELTLTDSHAI LVYLCDTFAP PGHTLALPDA LTRAKVFNML
110 120 130 140 150
CFNNGCLFQR DAEVMRKIFS GAITDPTQHL KPIEAAIDAL EQFLQRSRYT
160 170 180 190 200
AHDQLSVADF AIVATLSTVA IFVPLPADRW PRVCEWFAVM EALPYYNDQN
210
RVGLDMLRKH LAGKIKL
Length:217
Mass (Da):24,359
Last modified:March 1, 2002 - v1
Checksum:i0344C09C2F977C05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY070257 mRNA. Translation: AAL59656.1.
AAAB01008984 Genomic DNA. Translation: EAA43406.1.
RefSeqiXP_319963.1. XM_319963.2.

Genome annotation databases

GeneIDi1280151.
KEGGiaga:AgaP_AGAP009190.
VectorBaseiAGAP009189. Anopheles gambiae.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY070257 mRNA. Translation: AAL59656.1.
AAAB01008984 Genomic DNA. Translation: EAA43406.1.
RefSeqiXP_319963.1. XM_319963.2.

3D structure databases

ProteinModelPortaliQ8WQJ5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7165.AGAP009190-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1280151.
KEGGiaga:AgaP_AGAP009190.
VectorBaseiAGAP009189. Anopheles gambiae.

Organism-specific databases

CTDi1280151.

Phylogenomic databases

eggNOGiCOG0625.
HOGENOMiHOG000125741.
InParanoidiQ8WQJ5.
KOiK00799.
OMAiFFECSFL.
OrthoDBiEOG70089Q.
PhylomeDBiQ8WQJ5.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R., Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C., Kokoza E., Koutsos A., Letunic I., Levitsky A., Liang Y., Lin J.J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
    Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PESTImported.
  2. The Anopheles Genome Sequencing Consortium
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PESTImported.
  3. "Heterologous expression of four glutathione transferase genes genetically linked to a major insecticide-resistance locus from the malaria vector Anopheles gambiae."
    Ortelli F., Rossiter L.C., Vontas J., Ranson H., Hemingway J.
    Biochem. J. 373:957-963(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ZAN/UImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PESTImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PESTImported.
  6. VectorBase
    Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PESTImported.

Entry informationi

Entry nameiQ8WQJ5_ANOGA
AccessioniPrimary (citable) accession number: Q8WQJ5
Secondary accession number(s): Q7PVT1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: June 24, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.