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Q8W3M6

- UBCP_ARATH

UniProt

Q8W3M6 - UBCP_ARATH

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Protein

Ubiquitin-like domain-containing CTD phosphatase

Gene

At4g06599

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Magnesium.By similarity

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Enzyme and pathway databases

BioCyciARA:AT4G06599-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-like domain-containing CTD phosphatase (EC:3.1.3.16)
Alternative name(s):
Nuclear proteasome inhibitor UBLCP1
Gene namesi
Ordered Locus Names:At4g06599
ORF Names:T11G11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 4

Organism-specific databases

TAIRiAT4G06599.

Subcellular locationi

Nucleus By similarity
Note: Colocalizes with nuclear proteasomes.By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 340340Ubiquitin-like domain-containing CTD phosphatasePRO_0000305941Add
BLAST

Proteomic databases

PaxDbiQ8W3M6.
PRIDEiQ8W3M6.

Expressioni

Gene expression databases

GenevestigatoriQ8W3M6.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G06599.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ8W3M6.
SMRiQ8W3M6. Positions 22-329.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 10178Ubiquitin-likePROSITE-ProRule annotationAdd
BLAST
Domaini151 – 312162FCP1 homologyPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni151 – 312162PhosphataseBy similarityAdd
BLAST

Domaini

The Ubiquitin-like domain mediates interaction with proteasomes.By similarity

Sequence similaritiesi

Contains 1 FCP1 homology domain.PROSITE-ProRule annotation
Contains 1 ubiquitin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG310886.
HOGENOMiHOG000231279.
InParanoidiQ8W3M6.
KOiK17618.
OMAiELNPPRE.
PhylomeDBiQ8W3M6.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR011943. HAD-SF_hydro_IIID.
IPR004274. NIF.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF03031. NIF. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00577. CPDc. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR02245. HAD_IIID1. 1 hit.
PROSITEiPS50969. FCP1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8W3M6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASSSSSPTP SAAAAVSPLT EEELTLTVKW NGKEYTVRIC ADDSVAELKR
60 70 80 90 100
RICLLTTVLP KRQKLLYPKI GNKLSDDSLL LSSISFKPSL KMTMIGTVED
110 120 130 140 150
DIIVDQAESP EIVDDFELGK EEAVDVKDKE VNKQKLRRRI DQYKINLRTP
160 170 180 190 200
CRQGKKLLVL DIDYTLFDHR STAENPLQLM RPYLHEFLTA AYAEYDIMIW
210 220 230 240 250
SATSMKWVEL KMTELGVLNN PNYKVTALLD HLAMITVQSD TRGIFDCKPL
260 270 280 290 300
GLIWALLPEF YNPGNTIMFD DLRRNFVMNP QNGLTIKPFR KAHANRDTDQ
310 320 330 340
ELVKLTQYLL TIAELSDLSS LHHSRWESFS QDNVKRRRQE
Length:340
Mass (Da):38,956
Last modified:March 1, 2002 - v1
Checksum:i1B9D23EF3E424382
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB073160 Genomic DNA. Translation: BAB83612.1.
CP002687 Genomic DNA. Translation: AEE82552.1.
RefSeqiNP_849320.1. NM_178989.3.
UniGeneiAt.23843.
At.44411.

Genome annotation databases

EnsemblPlantsiAT4G06599.1; AT4G06599.1; AT4G06599.
GeneIDi826068.
KEGGiath:AT4G06599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB073160 Genomic DNA. Translation: BAB83612.1 .
CP002687 Genomic DNA. Translation: AEE82552.1 .
RefSeqi NP_849320.1. NM_178989.3.
UniGenei At.23843.
At.44411.

3D structure databases

ProteinModelPortali Q8W3M6.
SMRi Q8W3M6. Positions 22-329.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT4G06599.1-P.

Proteomic databases

PaxDbi Q8W3M6.
PRIDEi Q8W3M6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT4G06599.1 ; AT4G06599.1 ; AT4G06599 .
GeneIDi 826068.
KEGGi ath:AT4G06599.

Organism-specific databases

TAIRi AT4G06599.

Phylogenomic databases

eggNOGi NOG310886.
HOGENOMi HOG000231279.
InParanoidi Q8W3M6.
KOi K17618.
OMAi ELNPPRE.
PhylomeDBi Q8W3M6.

Enzyme and pathway databases

BioCyci ARA:AT4G06599-MONOMER.

Miscellaneous databases

PROi Q8W3M6.

Gene expression databases

Genevestigatori Q8W3M6.

Family and domain databases

Gene3Di 3.40.50.1000. 1 hit.
InterProi IPR023214. HAD-like_dom.
IPR011943. HAD-SF_hydro_IIID.
IPR004274. NIF.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF03031. NIF. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view ]
SMARTi SM00577. CPDc. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view ]
SUPFAMi SSF54236. SSF54236. 1 hit.
SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR02245. HAD_IIID1. 1 hit.
PROSITEi PS50969. FCP1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4."
    Kumekawa N., Hosouchi T., Tsuruoka H., Kotani H.
    DNA Res. 8:285-290(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.

Entry informationi

Entry nameiUBCP_ARATH
AccessioniPrimary (citable) accession number: Q8W3M6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3