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Protein

Ubiquitin-like domain-containing CTD phosphatase

Gene

At4g06599

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-like domain-containing CTD phosphatase (EC:3.1.3.16)
Alternative name(s):
Nuclear proteasome inhibitor UBLCP1
Gene namesi
Ordered Locus Names:At4g06599
ORF Names:T11G11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G06599
TAIRilocus:1005716300 AT4G06599

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003059411 – 340Ubiquitin-like domain-containing CTD phosphataseAdd BLAST340

Proteomic databases

PaxDbiQ8W3M6
PRIDEiQ8W3M6

Expressioni

Gene expression databases

ExpressionAtlasiQ8W3M6 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G06599.1

Structurei

3D structure databases

ProteinModelPortaliQ8W3M6
SMRiQ8W3M6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 101Ubiquitin-likePROSITE-ProRule annotationAdd BLAST78
Domaini151 – 312FCP1 homologyPROSITE-ProRule annotationAdd BLAST162

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni151 – 312PhosphataseBy similarityAdd BLAST162

Domaini

The Ubiquitin-like domain mediates interaction with proteasomes.By similarity

Phylogenomic databases

eggNOGiKOG1605 Eukaryota
COG5190 LUCA
HOGENOMiHOG000231279
InParanoidiQ8W3M6
KOiK17618
OMAiFKLMMVG
OrthoDBiEOG09360FVA
PhylomeDBiQ8W3M6

Family and domain databases

Gene3Di3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR004274 FCP1_dom
IPR036412 HAD-like_sf
IPR011943 HAD-SF_hydro_IIID
IPR023214 HAD_sf
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
PfamiView protein in Pfam
PF03031 NIF, 1 hit
PF00240 ubiquitin, 1 hit
SMARTiView protein in SMART
SM00577 CPDc, 1 hit
SM00213 UBQ, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
SSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR02245 HAD_IIID1, 1 hit
PROSITEiView protein in PROSITE
PS50969 FCP1, 1 hit
PS50053 UBIQUITIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8W3M6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSSSPTP SAAAAVSPLT EEELTLTVKW NGKEYTVRIC ADDSVAELKR
60 70 80 90 100
RICLLTTVLP KRQKLLYPKI GNKLSDDSLL LSSISFKPSL KMTMIGTVED
110 120 130 140 150
DIIVDQAESP EIVDDFELGK EEAVDVKDKE VNKQKLRRRI DQYKINLRTP
160 170 180 190 200
CRQGKKLLVL DIDYTLFDHR STAENPLQLM RPYLHEFLTA AYAEYDIMIW
210 220 230 240 250
SATSMKWVEL KMTELGVLNN PNYKVTALLD HLAMITVQSD TRGIFDCKPL
260 270 280 290 300
GLIWALLPEF YNPGNTIMFD DLRRNFVMNP QNGLTIKPFR KAHANRDTDQ
310 320 330 340
ELVKLTQYLL TIAELSDLSS LHHSRWESFS QDNVKRRRQE
Length:340
Mass (Da):38,956
Last modified:March 1, 2002 - v1
Checksum:i1B9D23EF3E424382
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB073160 Genomic DNA Translation: BAB83612.1
CP002687 Genomic DNA Translation: AEE82552.1
RefSeqiNP_849320.1, NM_178989.3
UniGeneiAt.23843
At.44411

Genome annotation databases

EnsemblPlantsiAT4G06599.1; AT4G06599.1; AT4G06599
GeneIDi826068
GrameneiAT4G06599.1; AT4G06599.1; AT4G06599
KEGGiath:AT4G06599

Similar proteinsi

Entry informationi

Entry nameiUBCP_ARATH
AccessioniPrimary (citable) accession number: Q8W3M6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names

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