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Q8W3M6 (UBCP_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquitin-like domain-containing CTD phosphatase

EC=3.1.3.16
Alternative name(s):
Nuclear proteasome inhibitor UBLCP1
Gene names
Ordered Locus Names:At4g06599
ORF Names:T11G11
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length340 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Magnesium By similarity.

Subcellular location

Nucleus By similarity. Note: Colocalizes with nuclear proteasomes By similarity.

Domain

The Ubiquitin-like domain mediates interaction with proteasomes By similarity.

Sequence similarities

Contains 1 FCP1 homology domain.

Contains 1 ubiquitin-like domain.

Ontologies

Keywords
   Cellular componentNucleus
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdephosphorylation

Inferred from electronic annotation. Source: GOC

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 340340Ubiquitin-like domain-containing CTD phosphatase
PRO_0000305941

Regions

Domain24 – 10178Ubiquitin-like
Domain151 – 312162FCP1 homology
Region151 – 312162Phosphatase By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8W3M6 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 1B9D23EF3E424382

FASTA34038,956
        10         20         30         40         50         60 
MASSSSSPTP SAAAAVSPLT EEELTLTVKW NGKEYTVRIC ADDSVAELKR RICLLTTVLP 

        70         80         90        100        110        120 
KRQKLLYPKI GNKLSDDSLL LSSISFKPSL KMTMIGTVED DIIVDQAESP EIVDDFELGK 

       130        140        150        160        170        180 
EEAVDVKDKE VNKQKLRRRI DQYKINLRTP CRQGKKLLVL DIDYTLFDHR STAENPLQLM 

       190        200        210        220        230        240 
RPYLHEFLTA AYAEYDIMIW SATSMKWVEL KMTELGVLNN PNYKVTALLD HLAMITVQSD 

       250        260        270        280        290        300 
TRGIFDCKPL GLIWALLPEF YNPGNTIMFD DLRRNFVMNP QNGLTIKPFR KAHANRDTDQ 

       310        320        330        340 
ELVKLTQYLL TIAELSDLSS LHHSRWESFS QDNVKRRRQE 

« Hide

References

« Hide 'large scale' references
[1]"The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4."
Kumekawa N., Hosouchi T., Tsuruoka H., Kotani H.
DNA Res. 8:285-290(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB073160 Genomic DNA. Translation: BAB83612.1.
CP002687 Genomic DNA. Translation: AEE82552.1.
RefSeqNP_849320.1. NM_178989.3.
UniGeneAt.23843.
At.44411.

3D structure databases

ProteinModelPortalQ8W3M6.
SMRQ8W3M6. Positions 22-329.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT4G06599.1-P.

Proteomic databases

PaxDbQ8W3M6.
PRIDEQ8W3M6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT4G06599.1; AT4G06599.1; AT4G06599.
GeneID826068.
KEGGath:AT4G06599.

Organism-specific databases

TAIRAT4G06599.

Phylogenomic databases

eggNOGNOG310886.
HOGENOMHOG000231279.
InParanoidQ8W3M6.
KOK17618.
OMAELNPPRE.
PhylomeDBQ8W3M6.
ProtClustDBCLSN2690761.

Enzyme and pathway databases

BioCycARA:AT4G06599-MONOMER.

Gene expression databases

GenevestigatorQ8W3M6.

Family and domain databases

Gene3D3.40.50.1000. 1 hit.
InterProIPR023214. HAD-like_dom.
IPR011943. HAD-SF_hydro_IIID.
IPR004274. NIF.
IPR000626. Ubiquitin_dom.
[Graphical view]
PfamPF03031. NIF. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTSM00577. CPDc. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMSSF56784. SSF56784. 1 hit.
TIGRFAMsTIGR02245. HAD_IIID1. 1 hit.
PROSITEPS50969. FCP1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ8W3M6.

Entry information

Entry nameUBCP_ARATH
AccessionPrimary (citable) accession number: Q8W3M6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: March 1, 2002
Last modified: March 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names