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Protein

Probable protein phosphatase 2C 11

Gene

At1g43900

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi159Manganese 1By similarity1
Metal bindingi159Manganese 2By similarity1
Metal bindingi160Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi320Manganese 2By similarity1
Metal bindingi359Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 11 (EC:3.1.3.16)
Short name:
AtPP2C11
Gene namesi
Ordered Locus Names:At1g43900
ORF Names:F28H19.16, F9C16.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G43900.
TAIRilocus:2029172. AT1G43900.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679421 – 371Probable protein phosphatase 2C 11Add BLAST371

Proteomic databases

PaxDbiQ8VZN9.
PRIDEiQ8VZN9.

PTM databases

iPTMnetiQ8VZN9.

Expressioni

Gene expression databases

GenevisibleiQ8VZN9. AT.

Interactioni

Protein-protein interaction databases

BioGridi26214. 1 interactor.
IntActiQ8VZN9. 1 interactor.
MINTiMINT-8390558.
STRINGi3702.AT1G43900.1.

Structurei

3D structure databases

ProteinModelPortaliQ8VZN9.
SMRiQ8VZN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini123 – 368PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST246

Sequence similaritiesi

Belongs to the PP2C family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233896.
InParanoidiQ8VZN9.
KOiK17506.
OMAiIVVRFEV.
OrthoDBiEOG09360FJK.
PhylomeDBiQ8VZN9.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiView protein in Pfam
PF00481. PP2C. 1 hit.
SMARTiView protein in SMART
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiView protein in PROSITE
PS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VZN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTRNVASS PIECVHLQTK PTTTLVRSFF FFLFNSQTIS SFIIFYLFLC
60 70 80 90 100
SFFWFCQSPN LTNPSPPPLS VAPLRGDANS PPPESSSSPA TKSSLMISSR
110 120 130 140 150
DPNALFSGGG ISFLAGVRTV KFSYGYSSLK GKRATMEDYF ETRISDVNGQ
160 170 180 190 200
MVAFFGVFDG HGGARTAEYL KNNLFKNLVS HDDFISDTKK AIVEVFKQTD
210 220 230 240 250
EEYLIEEAGQ PKNAGSTAAT AFLIGDKLIV ANVGDSRVVA SRNGSAVPLS
260 270 280 290 300
DDHKPDRSDE RQRIEDAGGF IIWAGTWRVG GILAVSRAFG DKQLKPYVIA
310 320 330 340 350
EPEIQEEDIS TLEFIVVASD GLWNVLSNKD AVAIVRDISD AETAARKLVQ
360 370
EGYARGSCDN ITCIVVRFEV S
Length:371
Mass (Da):40,583
Last modified:March 1, 2002 - v1
Checksum:i5579D3D23F1805E8
GO

Sequence cautioni

The sequence AAF79661 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006423 Genomic DNA. Translation: AAF63109.1.
AC022314 Genomic DNA. Translation: AAF79661.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE32006.1.
AY063973 mRNA. Translation: AAL36329.1.
AY117193 mRNA. Translation: AAM51268.1.
RefSeqiNP_175057.2. NM_103517.3.
UniGeneiAt.28764.
At.48277.

Genome annotation databases

EnsemblPlantsiAT1G43900.1; AT1G43900.1; AT1G43900.
GeneIDi840989.
GrameneiAT1G43900.1; AT1G43900.1; AT1G43900.
KEGGiath:AT1G43900.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiP2C11_ARATH
AccessioniPrimary (citable) accession number: Q8VZN9
Secondary accession number(s): Q9LP12, Q9MAQ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 1, 2002
Last modified: June 7, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families