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Q8VZN9

- P2C11_ARATH

UniProt

Q8VZN9 - P2C11_ARATH

Protein

Probable protein phosphatase 2C 11

Gene

At1g43900

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi159 – 1591Manganese 1By similarity
    Metal bindingi159 – 1591Manganese 2By similarity
    Metal bindingi160 – 1601Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi320 – 3201Manganese 2By similarity
    Metal bindingi359 – 3591Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT1G43900-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 11 (EC:3.1.3.16)
    Short name:
    AtPP2C11
    Gene namesi
    Ordered Locus Names:At1g43900
    ORF Names:F28H19.16, F9C16.6
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G43900.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 371371Probable protein phosphatase 2C 11PRO_0000367942Add
    BLAST

    Proteomic databases

    PaxDbiQ8VZN9.
    PRIDEiQ8VZN9.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8VZN9.

    Interactioni

    Protein-protein interaction databases

    BioGridi26214. 1 interaction.
    IntActiQ8VZN9. 1 interaction.
    MINTiMINT-8390558.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8VZN9.
    SMRiQ8VZN9. Positions 124-366.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei29 – 4921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini152 – 361210PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    InParanoidiQ8VZN9.
    KOiK17506.
    OMAiYETRISE.
    PhylomeDBiQ8VZN9.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8VZN9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKTRNVASS PIECVHLQTK PTTTLVRSFF FFLFNSQTIS SFIIFYLFLC    50
    SFFWFCQSPN LTNPSPPPLS VAPLRGDANS PPPESSSSPA TKSSLMISSR 100
    DPNALFSGGG ISFLAGVRTV KFSYGYSSLK GKRATMEDYF ETRISDVNGQ 150
    MVAFFGVFDG HGGARTAEYL KNNLFKNLVS HDDFISDTKK AIVEVFKQTD 200
    EEYLIEEAGQ PKNAGSTAAT AFLIGDKLIV ANVGDSRVVA SRNGSAVPLS 250
    DDHKPDRSDE RQRIEDAGGF IIWAGTWRVG GILAVSRAFG DKQLKPYVIA 300
    EPEIQEEDIS TLEFIVVASD GLWNVLSNKD AVAIVRDISD AETAARKLVQ 350
    EGYARGSCDN ITCIVVRFEV S 371
    Length:371
    Mass (Da):40,583
    Last modified:March 1, 2002 - v1
    Checksum:i5579D3D23F1805E8
    GO

    Sequence cautioni

    The sequence AAF79661.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC006423 Genomic DNA. Translation: AAF63109.1.
    AC022314 Genomic DNA. Translation: AAF79661.1. Sequence problems.
    CP002684 Genomic DNA. Translation: AEE32006.1.
    AY063973 mRNA. Translation: AAL36329.1.
    AY117193 mRNA. Translation: AAM51268.1.
    RefSeqiNP_175057.2. NM_103517.3.
    UniGeneiAt.28764.
    At.48277.

    Genome annotation databases

    EnsemblPlantsiAT1G43900.1; AT1G43900.1; AT1G43900.
    GeneIDi840989.
    KEGGiath:AT1G43900.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC006423 Genomic DNA. Translation: AAF63109.1 .
    AC022314 Genomic DNA. Translation: AAF79661.1 . Sequence problems.
    CP002684 Genomic DNA. Translation: AEE32006.1 .
    AY063973 mRNA. Translation: AAL36329.1 .
    AY117193 mRNA. Translation: AAM51268.1 .
    RefSeqi NP_175057.2. NM_103517.3.
    UniGenei At.28764.
    At.48277.

    3D structure databases

    ProteinModelPortali Q8VZN9.
    SMRi Q8VZN9. Positions 124-366.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 26214. 1 interaction.
    IntActi Q8VZN9. 1 interaction.
    MINTi MINT-8390558.

    Proteomic databases

    PaxDbi Q8VZN9.
    PRIDEi Q8VZN9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G43900.1 ; AT1G43900.1 ; AT1G43900 .
    GeneIDi 840989.
    KEGGi ath:AT1G43900.

    Organism-specific databases

    TAIRi AT1G43900.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    InParanoidi Q8VZN9.
    KOi K17506.
    OMAi YETRISE.
    PhylomeDBi Q8VZN9.

    Enzyme and pathway databases

    BioCyci ARA:AT1G43900-MONOMER.

    Gene expression databases

    Genevestigatori Q8VZN9.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C11_ARATH
    AccessioniPrimary (citable) accession number: Q8VZN9
    Secondary accession number(s): Q9LP12, Q9MAQ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3