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Protein

Transcription repressor OFP5

Gene

OFP5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homoedomain transcription factors. Required for embryo development.3 Publications

GO - Biological processi

  • embryo sac development Source: TAIR
  • negative regulation of transcription, DNA-templated Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription repressor OFP5
Alternative name(s):
Ovate family protein 5
Short name:
AtOFP5
Gene namesi
Name:OFP5
Ordered Locus Names:At4g18830
ORF Names:F13C5.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G18830.

Subcellular locationi

GO - Cellular componenti

  • cortical cytoskeleton Source: TAIR
  • nucleolus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Embryonic lethality when homozygous.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 349349Transcription repressor OFP5PRO_0000429674Add
BLAST

Proteomic databases

PaxDbiQ8VZN1.

Expressioni

Tissue specificityi

Expressed in roots, rosette and cauline leaves, and flower buds.1 Publication

Interactioni

Subunit structurei

Interacts with BLH1, BLH2, BLH3, BLH4, BLH6 and BLH10.1 Publication

Protein-protein interaction databases

BioGridi12910. 7 interactions.
IntActiQ8VZN1. 7 interactions.
STRINGi3702.AT4G18830.1.

Structurei

3D structure databases

ProteinModelPortaliQ8VZN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini286 – 34560OVATEPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 OVATE domain.PROSITE-ProRule annotationCurated

Phylogenomic databases

eggNOGiENOG410J060. Eukaryota.
ENOG410YW2J. LUCA.
HOGENOMiHOG000150656.
InParanoidiQ8VZN1.
OMAiIMENGIN.
OrthoDBiEOG09360HA2.
PhylomeDBiQ8VZN1.

Family and domain databases

InterProiIPR006458. Ovate_C.
[Graphical view]
PfamiPF04844. Ovate. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01568. A_thal_3678. 1 hit.
PROSITEiPS51754. OVATE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VZN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMRWGRKKPV SSSSSSGLSR ALPVSWFSKL SGSSDLKPAK EKKQDEKASQ
60 70 80 90 100
NISVKTSLSS TTRRSDIHEN SKRFQRVSVE KENSATRSAD KESNEKFEEI
110 120 130 140 150
MSSVRKKVRD FQKETCGFLE VEAMDRDNGT VILTPRIQVN RDKQRCERRD
160 170 180 190 200
QRLLEQKPKR SEQDAGVKVK KPARRTGTGG YSREDSVILG HTITKPAHQW
210 220 230 240 250
EKLKEVKLRE VKLKADQQRK SLYLKRELNR IGTKENNKVR VFSPRASEKC
260 270 280 290 300
RVKAIEDLKK AKQRAREHEL LIETADGGME NESFAVVKCS SDPQKDFRDS
310 320 330 340
MIEMIMENGI NHPEELKELL VCYLRLNTDE YHDMIISVFQ QVHNDFNFH
Length:349
Mass (Da):40,371
Last modified:March 1, 2002 - v1
Checksum:i95038EE8CE27F267
GO

Sequence cautioni

The sequence CAB52868 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAB78885 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021711 Genomic DNA. Translation: CAB52868.1. Different initiation.
AL161549 Genomic DNA. Translation: CAB78885.1. Different initiation.
CP002687 Genomic DNA. Translation: AEE84096.1.
AY063996 mRNA. Translation: AAL36352.1.
AY096608 mRNA. Translation: AAM20258.1.
PIRiD85212.
RefSeqiNP_193618.2. NM_117999.4.
UniGeneiAt.27110.

Genome annotation databases

EnsemblPlantsiAT4G18830.1; AT4G18830.1; AT4G18830.
GeneIDi827617.
GrameneiAT4G18830.1; AT4G18830.1; AT4G18830.
KEGGiath:AT4G18830.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021711 Genomic DNA. Translation: CAB52868.1. Different initiation.
AL161549 Genomic DNA. Translation: CAB78885.1. Different initiation.
CP002687 Genomic DNA. Translation: AEE84096.1.
AY063996 mRNA. Translation: AAL36352.1.
AY096608 mRNA. Translation: AAM20258.1.
PIRiD85212.
RefSeqiNP_193618.2. NM_117999.4.
UniGeneiAt.27110.

3D structure databases

ProteinModelPortaliQ8VZN1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi12910. 7 interactions.
IntActiQ8VZN1. 7 interactions.
STRINGi3702.AT4G18830.1.

Proteomic databases

PaxDbiQ8VZN1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G18830.1; AT4G18830.1; AT4G18830.
GeneIDi827617.
GrameneiAT4G18830.1; AT4G18830.1; AT4G18830.
KEGGiath:AT4G18830.

Organism-specific databases

TAIRiAT4G18830.

Phylogenomic databases

eggNOGiENOG410J060. Eukaryota.
ENOG410YW2J. LUCA.
HOGENOMiHOG000150656.
InParanoidiQ8VZN1.
OMAiIMENGIN.
OrthoDBiEOG09360HA2.
PhylomeDBiQ8VZN1.

Miscellaneous databases

PROiQ8VZN1.

Family and domain databases

InterProiIPR006458. Ovate_C.
[Graphical view]
PfamiPF04844. Ovate. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01568. A_thal_3678. 1 hit.
PROSITEiPS51754. OVATE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOFP5_ARATH
AccessioniPrimary (citable) accession number: Q8VZN1
Secondary accession number(s): Q9SNA9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 9, 2014
Last sequence update: March 1, 2002
Last modified: September 7, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Plants over-expressing OFP5 show kidney-shaped cotyledons, round and curled leaves, small rosette size, late flowering, reduced fertilization and round seeds.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.