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Protein

Diacylglycerol kinase 3

Gene

DGK3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity).By similarity

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processPlant defense, Stress response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT2G18730-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinase 3 (EC:2.7.1.107)
Short name:
AtDGK3
Short name:
DAG kinase 3
Alternative name(s):
Diglyceride kinase 3
Short name:
DGK 3
Gene namesi
Name:DGK3
Ordered Locus Names:At2g18730
ORF Names:MSF3.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G18730
TAIRilocus:2053978 AT2G18730

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004221111 – 488Diacylglycerol kinase 3Add BLAST488

Proteomic databases

PaxDbiQ8VZG1
PRIDEiQ8VZG1

PTM databases

iPTMnetiQ8VZG1
SwissPalmiQ8VZG1

Expressioni

Gene expression databases

ExpressionAtlasiQ8VZG1 baseline and differential
GenevisibleiQ8VZG1 AT

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

BioGridi1745, 7 interactors
IntActiQ8VZG1, 7 interactors
STRINGi3702.AT2G18730.1

Structurei

3D structure databases

ProteinModelPortaliQ8VZG1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini87 – 245DAGKcPROSITE-ProRule annotationAdd BLAST159

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1169 Eukaryota
ENOG410XQVB LUCA
HOGENOMiHOG000239559
InParanoidiQ8VZG1
KOiK00901
OMAiLMMPEYL
OrthoDBiEOG09360AZ1
PhylomeDBiQ8VZG1

Family and domain databases

Gene3Di3.40.50.10330, 1 hit
InterProiView protein in InterPro
IPR017438 ATP-NAD_kinase_N
IPR037607 DGK
IPR000756 Diacylglycerol_kin_accessory
IPR001206 Diacylglycerol_kinase_cat_dom
IPR016961 Diacylglycerol_kinase_pln
IPR016064 NAD/diacylglycerol_kinase_sf
PANTHERiPTHR11255 PTHR11255, 1 hit
PfamiView protein in Pfam
PF00609 DAGK_acc, 1 hit
PF00781 DAGK_cat, 1 hit
PIRSFiPIRSF030829 Diacylglycerol_kinase_pln, 1 hit
SMARTiView protein in SMART
SM00045 DAGKa, 1 hit
SM00046 DAGKc, 1 hit
SUPFAMiSSF111331 SSF111331, 2 hits
PROSITEiView protein in PROSITE
PS50146 DAGK, 1 hit

Sequencei

Sequence statusi: Complete.

Q8VZG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSPVSKTDA SKEKFVASRP STADSKTMRG CGLANLAWVG VDKVELRQRL
60 70 80 90 100
MMPEYLRLAM RDCIKRKDSS AIPDHLLLPG GAVADMAPHA PMVVFINPNS
110 120 130 140 150
GGRHGPVLKE RLQQLMSEEQ VFDLTEVKPH EFVRYGLGCL EKVAAEGDEC
160 170 180 190 200
AKECRARLRI MVAGGDGTVG WVLGCLGELN KDGKSQIPPV GVIPLGTGND
210 220 230 240 250
LSRSFGWGGS FPFAWRSAVK RTLHRASMGP VARLDSWKIL VSMPSGEVVD
260 270 280 290 300
PPYSLKPAEE NELDQGLDAG IDAPPLAKAY EGVFYNYLSI GMDAQVAYGF
310 320 330 340 350
HHLRNTKPYL AQGPISNKII YSSFGCSQGW FCTPCVNDPG LRGLRNIMKI
360 370 380 390 400
HIKKVNCSQW EEIAVPKNVR SIVALNLHSY GSGSHPWGNL KPDYLEKRGF
410 420 430 440 450
VEAHCDDGLI EIFGFKQGWH ASFVMAELIS AKHIAQAAAV RFELRGGDWR
460 470 480
DAFLQMDGEP WKQPMSTEYS TFVEIKKVPY QSLMINNE
Length:488
Mass (Da):53,881
Last modified:March 1, 2002 - v1
Checksum:i126012C84473CA3F
GO

Sequence cautioni

The sequence AAD08942 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005724 Genomic DNA Translation: AAD08942.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC06799.1
AY064982 mRNA Translation: AAL57635.1
AY141990 mRNA Translation: AAM98254.1
PIRiH84567
RefSeqiNP_849980.1, NM_179649.4
UniGeneiAt.27505

Genome annotation databases

EnsemblPlantsiAT2G18730.1; AT2G18730.1; AT2G18730
GeneIDi816388
GrameneiAT2G18730.1; AT2G18730.1; AT2G18730
KEGGiath:AT2G18730

Similar proteinsi

Entry informationi

Entry nameiDGK3_ARATH
AccessioniPrimary (citable) accession number: Q8VZG1
Secondary accession number(s): Q9ZV46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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