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Q8VZG1

- DGK3_ARATH

UniProt

Q8VZG1 - DGK3_ARATH

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Protein

Diacylglycerol kinase 3

Gene

DGK3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity).By similarity

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. diacylglycerol kinase activity Source: UniProtKB-EC
  3. NAD+ kinase activity Source: InterPro

GO - Biological processi

  1. defense response Source: UniProtKB-KW
  2. protein kinase C-activating G-protein coupled receptor signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Plant defense, Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT2G18730-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinase 3 (EC:2.7.1.107)
Short name:
AtDGK3
Short name:
DAG kinase 3
Alternative name(s):
Diglyceride kinase 3
Short name:
DGK 3
Gene namesi
Name:DGK3
Ordered Locus Names:At2g18730
ORF Names:MSF3.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G18730.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: TAIR
  2. plasma membrane Source: TAIR
  3. plasmodesma Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 488488Diacylglycerol kinase 3PRO_0000422111Add
BLAST

Proteomic databases

PaxDbiQ8VZG1.
PRIDEiQ8VZG1.

Expressioni

Gene expression databases

GenevestigatoriQ8VZG1.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

IntActiQ8VZG1. 7 interactions.
STRINGi3702.AT2G18730.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ8VZG1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini87 – 245159DAGKcPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 DAGKc domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG47311.
HOGENOMiHOG000239559.
InParanoidiQ8VZG1.
KOiK00901.
OMAiIKKVNCS.
PhylomeDBiQ8VZG1.

Family and domain databases

InterProiIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR000756. Diacylglycerol_kin_accessory.
IPR001206. Diacylglycerol_kinase_cat_dom.
IPR016961. Diacylglycerol_kinase_pln.
[Graphical view]
PfamiPF00609. DAGK_acc. 1 hit.
PF00781. DAGK_cat. 1 hit.
[Graphical view]
PIRSFiPIRSF030829. Diacylglycerol_kinase_pln. 1 hit.
SMARTiSM00045. DAGKa. 1 hit.
SM00046. DAGKc. 1 hit.
[Graphical view]
SUPFAMiSSF111331. SSF111331. 2 hits.
PROSITEiPS50146. DAGK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VZG1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSPVSKTDA SKEKFVASRP STADSKTMRG CGLANLAWVG VDKVELRQRL
60 70 80 90 100
MMPEYLRLAM RDCIKRKDSS AIPDHLLLPG GAVADMAPHA PMVVFINPNS
110 120 130 140 150
GGRHGPVLKE RLQQLMSEEQ VFDLTEVKPH EFVRYGLGCL EKVAAEGDEC
160 170 180 190 200
AKECRARLRI MVAGGDGTVG WVLGCLGELN KDGKSQIPPV GVIPLGTGND
210 220 230 240 250
LSRSFGWGGS FPFAWRSAVK RTLHRASMGP VARLDSWKIL VSMPSGEVVD
260 270 280 290 300
PPYSLKPAEE NELDQGLDAG IDAPPLAKAY EGVFYNYLSI GMDAQVAYGF
310 320 330 340 350
HHLRNTKPYL AQGPISNKII YSSFGCSQGW FCTPCVNDPG LRGLRNIMKI
360 370 380 390 400
HIKKVNCSQW EEIAVPKNVR SIVALNLHSY GSGSHPWGNL KPDYLEKRGF
410 420 430 440 450
VEAHCDDGLI EIFGFKQGWH ASFVMAELIS AKHIAQAAAV RFELRGGDWR
460 470 480
DAFLQMDGEP WKQPMSTEYS TFVEIKKVPY QSLMINNE
Length:488
Mass (Da):53,881
Last modified:March 1, 2002 - v1
Checksum:i126012C84473CA3F
GO

Sequence cautioni

The sequence AAD08942.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005724 Genomic DNA. Translation: AAD08942.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC06799.1.
AY064982 mRNA. Translation: AAL57635.1.
AY141990 mRNA. Translation: AAM98254.1.
PIRiH84567.
RefSeqiNP_849980.1. NM_179649.3.
UniGeneiAt.27505.

Genome annotation databases

EnsemblPlantsiAT2G18730.1; AT2G18730.1; AT2G18730.
GeneIDi816388.
KEGGiath:AT2G18730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005724 Genomic DNA. Translation: AAD08942.1 . Sequence problems.
CP002685 Genomic DNA. Translation: AEC06799.1 .
AY064982 mRNA. Translation: AAL57635.1 .
AY141990 mRNA. Translation: AAM98254.1 .
PIRi H84567.
RefSeqi NP_849980.1. NM_179649.3.
UniGenei At.27505.

3D structure databases

ProteinModelPortali Q8VZG1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q8VZG1. 7 interactions.
STRINGi 3702.AT2G18730.1-P.

Proteomic databases

PaxDbi Q8VZG1.
PRIDEi Q8VZG1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G18730.1 ; AT2G18730.1 ; AT2G18730 .
GeneIDi 816388.
KEGGi ath:AT2G18730.

Organism-specific databases

TAIRi AT2G18730.

Phylogenomic databases

eggNOGi NOG47311.
HOGENOMi HOG000239559.
InParanoidi Q8VZG1.
KOi K00901.
OMAi IKKVNCS.
PhylomeDBi Q8VZG1.

Enzyme and pathway databases

BioCyci ARA:AT2G18730-MONOMER.

Gene expression databases

Genevestigatori Q8VZG1.

Family and domain databases

InterProi IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR000756. Diacylglycerol_kin_accessory.
IPR001206. Diacylglycerol_kinase_cat_dom.
IPR016961. Diacylglycerol_kinase_pln.
[Graphical view ]
Pfami PF00609. DAGK_acc. 1 hit.
PF00781. DAGK_cat. 1 hit.
[Graphical view ]
PIRSFi PIRSF030829. Diacylglycerol_kinase_pln. 1 hit.
SMARTi SM00045. DAGKa. 1 hit.
SM00046. DAGKc. 1 hit.
[Graphical view ]
SUPFAMi SSF111331. SSF111331. 2 hits.
PROSITEi PS50146. DAGK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.

Entry informationi

Entry nameiDGK3_ARATH
AccessioniPrimary (citable) accession number: Q8VZG1
Secondary accession number(s): Q9ZV46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: March 1, 2002
Last modified: October 1, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3