Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8VZA1

- LAC11_ARATH

UniProt

Q8VZA1 - LAC11_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Laccase-11

Gene

LAC11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Binds 4 copper ions per monomer.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi81 – 811Copper 1; type 2By similarity
Metal bindingi83 – 831Copper 2; type 3By similarity
Metal bindingi126 – 1261Copper 2; type 3By similarity
Metal bindingi128 – 1281Copper 3; type 3By similarity
Metal bindingi458 – 4581Copper 4; type 1By similarity
Metal bindingi461 – 4611Copper 1; type 2By similarity
Metal bindingi463 – 4631Copper 3; type 3By similarity
Metal bindingi520 – 5201Copper 3; type 3By similarity
Metal bindingi521 – 5211Copper 4; type 1By similarity
Metal bindingi522 – 5221Copper 2; type 3By similarity
Metal bindingi526 – 5261Copper 4; type 1By similarity

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT5G03260-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-11 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 11
Diphenol oxidase 11
Urishiol oxidase 11
Gene namesi
Name:LAC11
Ordered Locus Names:At5g03260
ORF Names:F15A17_290, MOK16.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G03260.

Subcellular locationi

GO - Cellular componenti

  1. apoplast Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 557534Laccase-11PRO_0000283639Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi36 – 361N-linked (GlcNAc...)Sequence Analysis
Glycosylationi69 – 691N-linked (GlcNAc...)Sequence Analysis
Glycosylationi77 – 771N-linked (GlcNAc...)Sequence Analysis
Glycosylationi115 – 1151N-linked (GlcNAc...)Sequence Analysis
Glycosylationi240 – 2401N-linked (GlcNAc...)Sequence Analysis
Glycosylationi296 – 2961N-linked (GlcNAc...)Sequence Analysis
Glycosylationi323 – 3231N-linked (GlcNAc...)Sequence Analysis
Glycosylationi371 – 3711N-linked (GlcNAc...)Sequence Analysis
Glycosylationi381 – 3811N-linked (GlcNAc...)Sequence Analysis
Glycosylationi398 – 3981N-linked (GlcNAc...)Sequence Analysis
Glycosylationi416 – 4161N-linked (GlcNAc...)Sequence Analysis
Glycosylationi440 – 4401N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ8VZA1.

Expressioni

Tissue specificityi

Ubiquitous and constitutive.2 Publications

Gene expression databases

GenevestigatoriQ8VZA1.

Interactioni

Protein-protein interaction databases

BioGridi17163. 3 interactions.
STRINGi3702.AT5G03260.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ8VZA1.
SMRiQ8VZA1. Positions 23-536.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 147117Plastocyanin-like 1Add
BLAST
Domaini158 – 308151Plastocyanin-like 2Add
BLAST
Domaini406 – 541136Plastocyanin-like 3Add
BLAST

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ8VZA1.
OMAiNISRICN.
PhylomeDBiQ8VZA1.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8VZA1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKMGFLFLFC YLLAFLGYSP VDAAVKKYQF DVQVKNISRI CNAKPIVTVN
60 70 80 90 100
GMFPGPTVYA REGDRVIINV TNHVQYNMSI HWHGLKQYRN GWADGPAYIT
110 120 130 140 150
QCPIQTGQSY LYDFNVTGQR GTLWWHAHIL WLRATVYGAI VILPAPGKPY
160 170 180 190 200
PFPQPYQESN IILGEWWNKD VETAVNQANQ LGAPPPMSDA HTINGKPGPL
210 220 230 240 250
FPCSEKHTFV IEAEAGKTYL LRIINAALND ELFFGIAGHN MTVVEIDAVY
260 270 280 290 300
TKPFTTKAIL LGPGQTTNVL VKTDRSPNRY FMAASPFMDA PVSVDNKTVT
310 320 330 340 350
AILQYKGVPN TVLPILPKLP LPNDTSFALD YNGKLKSLNT PNFPALVPLK
360 370 380 390 400
VDRRLFYTIG LGINACPTCV NGTNLAASIN NITFIMPKTA LLKAHYSNIS
410 420 430 440 450
GVFRTDFPDR PPKAFNYTGV PLTANLGTST GTRLSRVKFN TTIELVLQDT
460 470 480 490 500
NLLTVESHPF HLHGYNFFVV GTGVGNFDPK KDPAKFNLVD PPERNTVGVP
510 520 530 540 550
TGGWAAIRFR ADNPGVWFMH CHLEVHTMWG LKMAFVVENG ETPELSVLPP

PKDYPSC
Length:557
Mass (Da):61,748
Last modified:March 1, 2002 - v1
Checksum:iF84A86C1E44B1E91
GO

Sequence cautioni

The sequence BAB08386.1 differs from that shown. Reason: Erroneous initiation.
The sequence CAB86093.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB005240 Genomic DNA. Translation: BAB08386.1. Different initiation.
AL163002 Genomic DNA. Translation: CAB86093.1. Different initiation.
CP002688 Genomic DNA. Translation: AED90578.1.
AY065128 mRNA. Translation: AAL38304.1.
AY081592 mRNA. Translation: AAM10154.1.
AK229950 mRNA. Translation: BAF01776.1.
PIRiT48347.
RefSeqiNP_195946.2. NM_120404.3.
UniGeneiAt.23614.
At.54702.

Genome annotation databases

EnsemblPlantsiAT5G03260.1; AT5G03260.1; AT5G03260.
GeneIDi831887.
KEGGiath:AT5G03260.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB005240 Genomic DNA. Translation: BAB08386.1 . Different initiation.
AL163002 Genomic DNA. Translation: CAB86093.1 . Different initiation.
CP002688 Genomic DNA. Translation: AED90578.1 .
AY065128 mRNA. Translation: AAL38304.1 .
AY081592 mRNA. Translation: AAM10154.1 .
AK229950 mRNA. Translation: BAF01776.1 .
PIRi T48347.
RefSeqi NP_195946.2. NM_120404.3.
UniGenei At.23614.
At.54702.

3D structure databases

ProteinModelPortali Q8VZA1.
SMRi Q8VZA1. Positions 23-536.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 17163. 3 interactions.
STRINGi 3702.AT5G03260.1-P.

Proteomic databases

PRIDEi Q8VZA1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G03260.1 ; AT5G03260.1 ; AT5G03260 .
GeneIDi 831887.
KEGGi ath:AT5G03260.

Organism-specific databases

TAIRi AT5G03260.

Phylogenomic databases

eggNOGi COG2132.
HOGENOMi HOG000241916.
InParanoidi Q8VZA1.
OMAi NISRICN.
PhylomeDBi Q8VZA1.

Enzyme and pathway databases

BioCyci ARA:AT5G03260-MONOMER.

Gene expression databases

Genevestigatori Q8VZA1.

Family and domain databases

Gene3Di 2.60.40.420. 3 hits.
InterProi IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view ]
Pfami PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 3 hits.
TIGRFAMsi TIGR03389. laccase. 1 hit.
PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence features of the 1.6 Mb regions covered by twenty physically assigned P1 clones."
    Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M., Miyajima N., Tabata S.
    DNA Res. 4:215-230(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
    Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
    , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
    Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 219-557.
    Strain: cv. Columbia.
  6. "Gene structure and molecular analysis of the laccase-like multicopper oxidase (LMCO) gene family in Arabidopsis thaliana."
    McCaig B.C., Meagher R.B., Dean J.F.D.
    Planta 221:619-636(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
  7. "Mutant identification and characterization of the laccase gene family in Arabidopsis."
    Cai X., Davis E.J., Ballif J., Liang M., Bushman E., Haroldsen V., Torabinejad J., Wu Y.
    J. Exp. Bot. 57:2563-2569(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.

Entry informationi

Entry nameiLAC11_ARATH
AccessioniPrimary (citable) accession number: Q8VZA1
Secondary accession number(s): Q0WM80, Q9LYV9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3