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Protein

Purple acid phosphatase 4

Gene

PAP4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactori

Protein has several cofactor binding sites:
  • Fe cationBy similarityNote: Binds 1 Fe cation per subunit.By similarity
  • Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi53IronBy similarity1
Metal bindingi86IronBy similarity1
Metal bindingi86ZincBy similarity1
Metal bindingi89IronBy similarity1
Metal bindingi124ZincBy similarity1
Metal bindingi218ZincBy similarity1
Active sitei227Proton donorBy similarity1
Metal bindingi253ZincBy similarity1
Metal bindingi255IronBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandIron, Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-ATH-196843 Vitamin B2 (riboflavin) metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Purple acid phosphatase 4 (EC:3.1.3.2)
Gene namesi
Name:PAP4
Ordered Locus Names:At1g25230
ORF Names:F4F7.38
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G25230
TAIRilocus:2033010 AT1G25230

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_000037280932 – 339Purple acid phosphatase 4Add BLAST308

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi61N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi284N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ8VYU7

Expressioni

Tissue specificityi

Expressed in roots, stems, leaves, flowers and siliques.1 Publication

Gene expression databases

ExpressionAtlasiQ8VYU7 baseline and differential
GenevisibleiQ8VYU7 AT

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi3702.AT1G25230.1

Structurei

3D structure databases

ProteinModelPortaliQ8VYU7
SMRiQ8VYU7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni253 – 255Substrate bindingBy similarity3

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG2679 Eukaryota
COG1409 LUCA
HOGENOMiHOG000239892
InParanoidiQ8VYU7
KOiK14379
OMAiGEEMDIN
OrthoDBiEOG09360IST
PhylomeDBiQ8VYU7

Family and domain databases

CDDicd07378 MPP_ACP5, 1 hit
Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR024927 Acid_Pase_5
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000898 Acid_Ptase_5, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8VYU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSKFDIGSL SIVMTLLICF LLLSLAPKLE AELATVQHAP NPDGSISFLV
60 70 80 90 100
IGDWGRHGLY NQSQVALQMG RIGEEMDINF VVSTGDNIYD NGMKSIDDPA
110 120 130 140 150
FQLSFSNIYT SPSLQKPWYL VLGNHDYRGD VEAQLSPILR SMDSRWICMR
160 170 180 190 200
SFIVDAEIAE LFFVDTTPFV DAYFLSPQDQ TYDWSGVSPR KSYLQTILTE
210 220 230 240 250
LEMGLRESSA KWKIVVGHHA IKSASIHGNT KELESLLLPI LEANKVDLYM
260 270 280 290 300
NGHDHCLQHI STSQSPIQFL TSGGGSKAWR GYYNWTTPED MKFFYDGQGF
310 320 330
MSVKITRSEL SVVFYDVSGN SLHKWDTSKM LDSDFYFPL
Length:339
Mass (Da):38,241
Last modified:March 1, 2002 - v1
Checksum:iA801B23B57C92609
GO

Sequence cautioni

The sequence AAG28815 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY842021 mRNA Translation: AAW29946.1
AC079374 Genomic DNA Translation: AAG28815.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE30591.1
AY069908 mRNA Translation: AAL47459.1
AY141997 mRNA Translation: AAM98261.1
PIRiH86381
RefSeqiNP_173894.2, NM_102332.4
UniGeneiAt.19616

Genome annotation databases

EnsemblPlantsiAT1G25230.1; AT1G25230.1; AT1G25230
AT1G25230.3; AT1G25230.3; AT1G25230
GeneIDi839105
GrameneiAT1G25230.1; AT1G25230.1; AT1G25230
AT1G25230.3; AT1G25230.3; AT1G25230
KEGGiath:AT1G25230

Similar proteinsi

Entry informationi

Entry nameiPPA4_ARATH
AccessioniPrimary (citable) accession number: Q8VYU7
Secondary accession number(s): Q9FRH2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: March 1, 2002
Last modified: April 25, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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