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Q8VYN6 (K6PF5_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
6-phosphofructokinase 5, chloroplastic

Short name=Phosphofructokinase 5
EC=2.7.1.11
Alternative name(s):
Phosphohexokinase 5
Gene names
Name:PFK5
Ordered Locus Names:At2g22480
ORF Names:F14M13.12
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length537 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. Ref.4

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.

Subcellular location

Plastidchloroplast Ref.4.

Tissue specificity

Expressed in roots, leaves, stems and flowers. Ref.4

Sequence similarities

Belongs to the phosphofructokinase family.

Sequence caution

The sequence AAD22353.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 5252Chloroplast Potential
Chain53 – 5374856-phosphofructokinase 5, chloroplastic
PRO_0000330772

Regions

Nucleotide binding199 – 2035ATP By similarity
Nucleotide binding336 – 3405ATP By similarity
Nucleotide binding354 – 37118ATP By similarity

Sites

Active site3091Proton acceptor By similarity

Amino acid modifications

Modified residue1471Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8VYN6 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 5A9DD3004D1ACC6A

FASTA53758,615
        10         20         30         40         50         60 
MDALSQAISS GISVPYKNNS SSLVPSHGLT SLILRKSRSP VNPSSRSRVS VRASEIQHSK 

        70         80         90        100        110        120 
TSASSIDLSD PDWKLKYEKD FEQRFSIPHI TDVLPDAEAI RSTFCLKMRS PTEDFVGGYP 

       130        140        150        160        170        180 
SDEEWHGYIN NNDRVLLKVI SYSSPTSAGA ECLDHDCSWV EQWIHRAGPR EKIYFRPEEV 

       190        200        210        220        230        240 
KAAIITCGGL CPGLNDVIRH IVITLEIYGV KNIVGIPFGY RGFSDKDLTE MPLSRKVVQN 

       250        260        270        280        290        300 
IHLSGGSLLG VSRGGPSVSE IVDSMEERGI NMLFVLGGNG THAGANAIHN ECRKRKIKVA 

       310        320        330        340        350        360 
VVGVPKTIDN DILHMDKTFG FDTAVEEAQR AINSAYIEAH SAYHGIGVVK LMGRNSGFIA 

       370        380        390        400        410        420 
MQASLASGQV DICLIPEVPF NLHGPNGVLK HLKYLIETKG SAVICVAEGA GQNFLEKTNA 

       430        440        450        460        470        480 
KDASGNAVLG DFGVYIQQET KKYFKEISTP IDVKYIDPTY MIRAVRANAS DGILCTVLGQ 

       490        500        510        520        530 
NAVHGAFAGY SGITVGIINT HYAYLPITEV IAYPKSVDPN SRMWHRCLTS TGQPDFI 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana."
Mustroph A., Sonnewald U., Biemelt S.
FEBS Lett. 581:2401-2410(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: CATALYTIC ACTIVITY, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC006592 Genomic DNA. Translation: AAD22353.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC07312.1.
AY070402 mRNA. Translation: AAL49898.1.
AY096578 mRNA. Translation: AAM20228.1.
PIRB84613.
RefSeqNP_850025.1. NM_179694.3.
UniGeneAt.28370.

3D structure databases

ProteinModelPortalQ8VYN6.
SMRQ8VYN6. Positions 108-531.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid2134. 1 interaction.
STRING3702.AT2G22480.1-P.

Proteomic databases

PaxDbQ8VYN6.
PRIDEQ8VYN6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G22480.1; AT2G22480.1; AT2G22480.
GeneID816781.
KEGGath:AT2G22480.

Organism-specific databases

TAIRAT2G22480.

Phylogenomic databases

eggNOGCOG0205.
HOGENOMHOG000016186.
InParanoidQ8VYN6.
KOK00850.
OMAWVGLMED.
PhylomeDBQ8VYN6.
ProtClustDBPLN02884.

Enzyme and pathway databases

BioCycARA:AT2G22480-MONOMER.
UniPathwayUPA00109; UER00182.

Gene expression databases

GenevestigatorQ8VYN6.

Family and domain databases

InterProIPR022953. Phosphofructokinase.
IPR000023. Phosphofructokinase_dom.
IPR012004. PyroP-dep_PFruKinase_TP0108.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000534. PPi_PFK_TP0108. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
ProtoNetSearch...

Entry information

Entry nameK6PF5_ARATH
AccessionPrimary (citable) accession number: Q8VYN6
Secondary accession number(s): Q9SJY6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: March 1, 2002
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names