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Protein

Nuclear transcription factor Y subunit A-4

Gene

NFYA4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi131 – 156NFYA/HAP2-typePROSITE-ProRule annotationAdd BLAST26

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • DNA binding transcription factor activity Source: TAIR

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: TAIR
  • regulation of timing of transition from vegetative to reproductive phase Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear transcription factor Y subunit A-4
Short name:
AtNF-YA-4
Gene namesi
Name:NFYA4
Ordered Locus Names:At2g34720
ORF Names:T29F13.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G34720
TAIRilocus:2061534 AT2G34720

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001987741 – 198Nuclear transcription factor Y subunit A-4Add BLAST198

Proteomic databases

PaxDbiQ8VY64
PRIDEiQ8VY64

PTM databases

iPTMnetiQ8VY64

Expressioni

Tissue specificityi

Expressed in stems, caulines, and senescent flowers.1 Publication

Gene expression databases

ExpressionAtlasiQ8VY64 baseline and differential
GenevisibleiQ8VY64 AT

Interactioni

Subunit structurei

Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding (By similarity).By similarity

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi3383, 13 interactors
IntActiQ8VY64, 27 interactors
STRINGi3702.AT2G34720.1

Structurei

3D structure databases

ProteinModelPortaliQ8VY64
SMRiQ8VY64
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi101 – 124Subunit association domain (SAD)Add BLAST24

Sequence similaritiesi

Belongs to the NFYA/HAP2 subunit family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1561 Eukaryota
COG5224 LUCA
HOGENOMiHOG000239782
InParanoidiQ8VY64
KOiK08064
OMAiYPGVQMQ
OrthoDBiEOG09360SA6
PhylomeDBiQ8VY64

Family and domain databases

InterProiView protein in InterPro
IPR018362 CCAAT-binding_factor_CS
IPR001289 NFYA
PANTHERiPTHR12632 PTHR12632, 1 hit
PfamiView protein in Pfam
PF02045 CBFB_NFYA, 1 hit
PRINTSiPR00616 CCAATSUBUNTB
SMARTiView protein in SMART
SM00521 CBF, 1 hit
PROSITEiView protein in PROSITE
PS00686 NFYA_HAP2_1, 1 hit
PS51152 NFYA_HAP2_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8VY64-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSVHELSD NNESHAKKER PDSQTRPQVP SGRSSESIDT NSVYSEPMAH
60 70 80 90 100
GLYPYPDPYY RSVFAQQAYL PHPYPGVQLQ LMGMQQPGVP LQCDAVEEPV
110 120 130 140 150
FVNAKQYHGI LRRRQSRAKL EARNRAIKAK KPYMHESRHL HAIRRPRGCG
160 170 180 190
GRFLNAKKEN GDHKEEEEAT SDENTSEASS SLRSEKLAMA TSGPNGRS
Length:198
Mass (Da):22,259
Last modified:March 1, 2002 - v1
Checksum:i665ACB070E64D00C
GO

Sequence cautioni

The sequence AAC16262 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003096 Genomic DNA Translation: AAC16262.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC09013.1
AY072414 mRNA Translation: AAL62406.1
AY114711 mRNA Translation: AAM48030.1
PIRiT01363
RefSeqiNP_850235.1, NM_179904.5
UniGeneiAt.37769

Genome annotation databases

EnsemblPlantsiAT2G34720.1; AT2G34720.1; AT2G34720
GeneIDi818037
GrameneiAT2G34720.1; AT2G34720.1; AT2G34720
KEGGiath:AT2G34720

Similar proteinsi

Entry informationi

Entry nameiNFYA4_ARATH
AccessioniPrimary (citable) accession number: Q8VY64
Secondary accession number(s): O64585
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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