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Protein

Nuclear transcription factor Y subunit A-4

Gene

NFYA4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi131 – 15626NFYA/HAP2-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: TAIR
  • regulation of timing of transition from vegetative to reproductive phase Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

ReactomeiR-ATH-2426168. Activation of gene expression by SREBF (SREBP).

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear transcription factor Y subunit A-4
Short name:
AtNF-YA-4
Gene namesi
Name:NFYA4
Ordered Locus Names:At2g34720
ORF Names:T29F13.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G34720.

Subcellular locationi

GO - Cellular componenti

  • CCAAT-binding factor complex Source: InterPro
  • nucleus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198Nuclear transcription factor Y subunit A-4PRO_0000198774Add
BLAST

Proteomic databases

PaxDbiQ8VY64.

PTM databases

iPTMnetiQ8VY64.

Expressioni

Tissue specificityi

Expressed in stems, caulines, and senescent flowers.1 Publication

Gene expression databases

GenevisibleiQ8VY64. AT.

Interactioni

Subunit structurei

Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding (By similarity).By similarity

Protein-protein interaction databases

BioGridi3383. 13 interactions.
IntActiQ8VY64. 5 interactions.
MINTiMINT-8064306.
STRINGi3702.AT2G34720.1.

Structurei

3D structure databases

ProteinModelPortaliQ8VY64.
SMRiQ8VY64. Positions 99-156.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi101 – 12424Subunit association domain (SAD)Add
BLAST

Sequence similaritiesi

Belongs to the NFYA/HAP2 subunit family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1561. Eukaryota.
COG5224. LUCA.
HOGENOMiHOG000239782.
InParanoidiQ8VY64.
KOiK08064.
OMAiNNESHAK.
OrthoDBiEOG09360SA6.
PhylomeDBiQ8VY64.

Family and domain databases

InterProiIPR018362. CCAAT-binding_factor_CS.
IPR001289. NFYA.
[Graphical view]
PANTHERiPTHR12632. PTHR12632. 1 hit.
PfamiPF02045. CBFB_NFYA. 1 hit.
[Graphical view]
PRINTSiPR00616. CCAATSUBUNTB.
SMARTiSM00521. CBF. 1 hit.
[Graphical view]
PROSITEiPS00686. NFYA_HAP2_1. 1 hit.
PS51152. NFYA_HAP2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VY64-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSVHELSD NNESHAKKER PDSQTRPQVP SGRSSESIDT NSVYSEPMAH
60 70 80 90 100
GLYPYPDPYY RSVFAQQAYL PHPYPGVQLQ LMGMQQPGVP LQCDAVEEPV
110 120 130 140 150
FVNAKQYHGI LRRRQSRAKL EARNRAIKAK KPYMHESRHL HAIRRPRGCG
160 170 180 190
GRFLNAKKEN GDHKEEEEAT SDENTSEASS SLRSEKLAMA TSGPNGRS
Length:198
Mass (Da):22,259
Last modified:March 1, 2002 - v1
Checksum:i665ACB070E64D00C
GO

Sequence cautioni

The sequence AAC16262 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003096 Genomic DNA. Translation: AAC16262.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC09013.1.
AY072414 mRNA. Translation: AAL62406.1.
AY114711 mRNA. Translation: AAM48030.1.
PIRiT01363.
RefSeqiNP_850235.1. NM_179904.4.
UniGeneiAt.37769.

Genome annotation databases

EnsemblPlantsiAT2G34720.1; AT2G34720.1; AT2G34720.
GeneIDi818037.
GrameneiAT2G34720.1; AT2G34720.1; AT2G34720.
KEGGiath:AT2G34720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003096 Genomic DNA. Translation: AAC16262.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC09013.1.
AY072414 mRNA. Translation: AAL62406.1.
AY114711 mRNA. Translation: AAM48030.1.
PIRiT01363.
RefSeqiNP_850235.1. NM_179904.4.
UniGeneiAt.37769.

3D structure databases

ProteinModelPortaliQ8VY64.
SMRiQ8VY64. Positions 99-156.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi3383. 13 interactions.
IntActiQ8VY64. 5 interactions.
MINTiMINT-8064306.
STRINGi3702.AT2G34720.1.

PTM databases

iPTMnetiQ8VY64.

Proteomic databases

PaxDbiQ8VY64.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G34720.1; AT2G34720.1; AT2G34720.
GeneIDi818037.
GrameneiAT2G34720.1; AT2G34720.1; AT2G34720.
KEGGiath:AT2G34720.

Organism-specific databases

TAIRiAT2G34720.

Phylogenomic databases

eggNOGiKOG1561. Eukaryota.
COG5224. LUCA.
HOGENOMiHOG000239782.
InParanoidiQ8VY64.
KOiK08064.
OMAiNNESHAK.
OrthoDBiEOG09360SA6.
PhylomeDBiQ8VY64.

Enzyme and pathway databases

ReactomeiR-ATH-2426168. Activation of gene expression by SREBF (SREBP).

Miscellaneous databases

PROiQ8VY64.

Gene expression databases

GenevisibleiQ8VY64. AT.

Family and domain databases

InterProiIPR018362. CCAAT-binding_factor_CS.
IPR001289. NFYA.
[Graphical view]
PANTHERiPTHR12632. PTHR12632. 1 hit.
PfamiPF02045. CBFB_NFYA. 1 hit.
[Graphical view]
PRINTSiPR00616. CCAATSUBUNTB.
SMARTiSM00521. CBF. 1 hit.
[Graphical view]
PROSITEiPS00686. NFYA_HAP2_1. 1 hit.
PS51152. NFYA_HAP2_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNFYA4_ARATH
AccessioniPrimary (citable) accession number: Q8VY64
Secondary accession number(s): O64585
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: March 1, 2002
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.