Reviewed, UniProtKB/Swiss-Prot Q8VW55 (OTCC_OENOE)

Names and origin

Protein names

Recommended name:
    Ornithine carbamoyltransferase, catabolic
      Short name=OTCase
    EC=2.1.3.3

Gene names

Name:

arcB

Organism

Oenococcus oeni (Leuconostoc oenos)

Taxonomic identifier

1247 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Oenococcus

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. HAMAP MF_01109
Pathway	Amino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 2/2. HAMAP MF_01109
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the ATCase/OTCase family.

Ontologies

Keywords
Biological process	Arginine metabolism
Cellular component	Cytoplasm
Molecular function	Transferase
Gene Ontology (GO)
Biological process	arginine metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	ornithine carbamoyltransferase complex Inferred from electronic annotation. Source: InterPro
Molecular function	amino acid binding Inferred from electronic annotation. Source: InterPro ornithine carbamoyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 351	351	Ornithine carbamoyltransferase, catabolic HAMAP MF_01109		PRO_0000112976
Regions
	Region	70 – 74	5	Carbamoyl phosphate binding By similarity
	Region	285 – 288	4	Ornithine binding By similarity
Sites
	Binding site	121	1	Carbamoyl phosphate By similarity
	Binding site	148	1	Carbamoyl phosphate By similarity
	Site	45	1	Important for structural integrity By similarity
	Site	161	1	Important for structural integrity By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8VW55-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: FB610D09BCADB32D	FASTA	351	39,789
	10 20 30 40 50 60 MEQKLGNLVK KNVVNSVFQG RSLLAEKDFT PMELEYLIDF ALHLKALKKL GISHRYLEGK 70 80 90 100 110 120 NIALLFEKTS TRTRSAFTTA SIDLGAHPEF LGSNDIQLGK KESVEDTARV LGSMFDGIEF 130 140 150 160 170 180 RGFKQSVVDD LARYSGVPVW NGLTDEWHPT QMLADFMTIK ENFGHIKNIN LSYMGDGRNN 190 200 210 220 230 240 TANSLLITGS MLGANIRIVS PKELQPSEKT TELAKKFAEK SGSRFLITDN IDEGVSKTNV 250 260 270 280 290 300 LYTDVWVSMG ESDWEDRVKL LKPYQVNMET IRKTSTPDDQ LIFMHCLPAF HDINTDYGHE 310 320 330 340 350 IFEKYGIKEM EVTDEVFRSI YARQFEEAEN RMHSIKAIMA ATLGNLFIPH V

References

[1]

"The arcABC gene cluster encoding the arginine deiminase pathway of Oenococcus oeni, and arginine induction of a CRP-like gene." Tonon T., Bourdineaud J.P., Lonvaud-Funel A. Res. Microbiol. 152:653-661(2001) [PubMed: 11605985] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 23279 / DSM 20252 / JCM 6125 / NCDO 1674 / NCIMB 11648.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF124851 Genomic DNA. Translation: AAL33871.1.
3D structure databases
HSSP	HSSP built from PDB template 1AKM based on UniProtKB P04391.
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.1.3.3. 259411.
Family and domain databases
HAMAP	MF_01109. [Tree]
InterPro	IPR006132. Asp/Orn_carbamoyltranf_P_bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR006131. Asp_carbamoyltransf_Asp/Orn_bd. IPR002292. Orn_carbamltrans. [Graphical view]
Pfam	PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view]
PRINTS	PR00100. AOTCASE. PR00102. OTCASE.
TIGRFAMs	TIGR00658. orni_carb_tr. 1 hit.
PROSITE	PS00097. CARBAMOYLTRANSFERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OTCC_OENOE

Accession

Primary (citable) accession number: Q8VW55

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2003
Last sequence update:	March 1, 2002
Last modified:	July 28, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)