Unreviewed, UniProtKB/TrEMBL Q8VQN0 (Q8VQN0_PROFR)

Names and origin

Protein names	Submitted name:     Methylmalonyl CoA epimerase EMBL AAL57846.1     EC=5.1.99.1
Organism	Propionibacterium freudenreichii subsp. shermanii EMBL AAL57846.1
Taxonomic identifier	1752 [NCBI]
Taxonomic lineage	Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Propionibacteriaceae › Propionibacterium

Protein attributes

Sequence length	148 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Molecular function	Isomerase
Gene Ontology (GO)
Molecular function	methylmalonyl-CoA epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8VQN0-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 258F88915E03F598	FASTA	148	16,717
	10 20 30 40 50 60 MSNEDLFICI DHVAYACPDA DEASKYYQET FGWHELHREE NPEQGVVEIM MAPAAKLTEH 70 80 90 100 110 120 MTQVQVMAPL NDESTVAKWL AKHNGRAGLH HMAWRVDDID AVSATLRERG VQLLYDEPKL 130 140 GTGGNRINFM HPKSGKGVLI ELTQYPKN

References

[1]	"Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold." McCarthy A.A., Baker H.M., Shewry S.C., Patchett M.L., Baker E.N. Structure 9:637-646(2001) [PubMed: 11470438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NCIB 9885 EMBL AAL57846.1.
[2]	"The structural genes for methylmalonyl CoA metabolism in Propionibacterium shermanii." Davis N.K. Thesis (1986), University of Cambridge, null Cited for: NUCLEOTIDE SEQUENCE. Strain: NCIB 9885 EMBL AAL57846.1.
[3]	Davis N.K., Leadlay P.F., Patchett M.L. Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: NCIB 9885 EMBL AAL57846.1.
[4]	"Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli." Dayem L.C., Santi D.V., Pfeifer B.A., Khosla C., Kealey J.T. Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AY046899 Genomic DNA. Translation: AAL02261.1.
AF454511 Genomic DNA. Translation: AAL57846.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1JC4	X-ray	2.00	A/B/C/D	1-148	[»]
1JC5	X-ray	2.20	A/B/C/D/E/F	1-148	[»]

ModBase

Search...

Enzyme and pathway databases

BioCyc

MetaCyc:MON-13075.

Family and domain databases

InterPro

IPR004360. Glyas_bleo-R_dOase.
IPR017515. MeMalonyl-CoA_epimerase.
[Graphical view]

Pfam

PF00903. Glyoxalase. 1 hit.
[Graphical view]

TIGRFAMs

TIGR03081. metmalonyl_epim. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q8VQN0_PROFR

Accession

Primary (citable) accession number: Q8VQN0

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	October 14, 2008
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)