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Q8VQN0 (Q8VQN0_PROFR) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length148 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Molecular functionIsomerase EMBL AAL57846.1
   Technical term3D-structure PDB 1JC4 PDB 1JC5
Gene Ontology (GO)
   Molecular_functionmethylmalonyl-CoA epimerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region58 – 603Sulfate 3 binding PDB 1JC4 PDB 1JC5
Region58 – 603Sulfate 4 binding PDB 1JC4
Region116 – 1172Sulfate 5 binding PDB 1JC5

Sites

Binding site481Sulfate 1 PDB 1JC5
Binding site651Sulfate 1 PDB 1JC5
Binding site651Sulfate 2 PDB 1JC4 PDB 1JC5
Binding site1221Sulfate 1 PDB 1JC5
Binding site1221Sulfate 2 PDB 1JC4 PDB 1JC5
Binding site1411Sulfate 1 PDB 1JC5
Binding site1411Sulfate 2 PDB 1JC4 PDB 1JC5

Sequences

Sequence LengthMass (Da)Tools
Q8VQN0 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 258F88915E03F598

FASTA14816,717
        10         20         30         40         50         60 
MSNEDLFICI DHVAYACPDA DEASKYYQET FGWHELHREE NPEQGVVEIM MAPAAKLTEH 

        70         80         90        100        110        120 
MTQVQVMAPL NDESTVAKWL AKHNGRAGLH HMAWRVDDID AVSATLRERG VQLLYDEPKL 

       130        140 
GTGGNRINFM HPKSGKGVLI ELTQYPKN 

« Hide

References

[1]"The structural genes for methylmalonyl CoA metabolism in Propionibacterium shermanii."
Davis N.K.
Thesis (1986), University of Cambridge
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NCIB 9885 EMBL AAL57846.1.
[2]"Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold."
McCarthy A.A., Baker H.M., Shewry S.C., Patchett M.L., Baker E.N.
Structure 9:637-646(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NCIB 9885 EMBL AAL57846.1.
[3]"Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli."
Dayem L.C., Santi D.V., Pfeifer B.A., Khosla C., Kealey J.T.
Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[4]Davis N.K., Leadlay P.F., Patchett M.L.
Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NCIB 9885 EMBL AAL57846.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY046899 Genomic DNA. Translation: AAL02261.1.
AF454511 Genomic DNA. Translation: AAL57846.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1JC4X-ray2.00A/B/C/D1-148[»]
1JC5X-ray2.20A/B/C/D/E/F1-148[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-13075.

Family and domain databases

Gene3D3.10.180.10. 1 hit.
InterProIPR029068. Glyas_Bleomycin-R_OHBP_Dase.
IPR017515. MeMalonyl-CoA_epimerase.
[Graphical view]
SUPFAMSSF54593. SSF54593. 1 hit.
TIGRFAMsTIGR03081. metmalonyl_epim. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ8VQN0.

Entry information

Entry nameQ8VQN0_PROFR
AccessionPrimary (citable) accession number: Q8VQN0
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: June 11, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)