Q8VL04 (ARGR2_LACPL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine repressor

Gene names

Name:	argR2
Ordered Locus Names:	lp_1604

Organism

Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)

Taxonomic identifier

220668 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Regulates arginine biosynthesis genes. HAMAP MF_00173
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis. [regulation] HAMAP MF_00173
Subcellular location	Cytoplasm Probable HAMAP MF_00173.
Sequence similarities	Belongs to the ArgR family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis Transcription Transcription regulation
Cellular component	Cytoplasm
Ligand	DNA-binding
Molecular function	Repressor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 152	152	Arginine repressor HAMAP MF_00173		PRO_0000205096

Sequences

	Sequence		Length	Mass (Da)
	Q8VL04 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: A5CEA089716ED18D	FASTA	152	17,452
	10 20 30 40 50 60 MKKQERQRYI KRLLSSNEIE RQEDFVKLLR AEDIDVTQAT ISRDIKDMQL VKVPSATGGY 70 80 90 100 110 120 HYSMPVQKQM DTEKKLKRTL KDAYVSYATQ DKFVLIKVLP GNGPALATLI EAMHYDEIFG 130 140 150 TLGDDAHVLI ICKSLAMTLE LQQKIQRLLS DH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Two arginine repressors regulate arginine biosynthesis in Lactobacillus plantarum." Nicoloff H., Arsene-Ploetze F., Malandain C., Kleerebezem M., Bringel F. J. Bacteriol. 186:6059-6069(2004) [PubMed: 15342575] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 8014 / CCM 1904 / DSM 20205 / NCDO 82 / NCIB 6376.
[2]	"Complete genome sequence of Lactobacillus plantarum WCFS1." Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M., Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M., Siezen R.J. Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003) [PubMed: 12566566] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-793 / NCIMB 8826 / WCFS1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF451891 Genomic DNA. Translation: AAL48253.1. AL935263 Genomic DNA. Translation: CCC78918.1.
RefSeq	NP_785197.1. NC_004567.1.
3D structure databases
ProteinModelPortal	Q8VL04.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1063628.
GenomeReviews	Gene locus lp_1604 in contig AL935263_GR.
KEGG	lpl:lp_1604.
NMPDR	fig|220668.1.peg.1331.
PATRIC	22249423. VBILacPla27411_1353.
Phylogenomic databases
HOGENOM	HBG697909.
OMA	QRIFATI.
ProtClustDB	CLSK581449.
Enzyme and pathway databases
BioCyc	LPLA220668:LP_1604-MONOMER.
Family and domain databases
HAMAP	MF_00173. Arg_repressor. [Tree]
InterPro	IPR001669. Arg_repress. IPR020899. Arg_repress_C. IPR020900. Arg_repress_DNA-bd. IPR011991. WHTH_trsnscrt_rep_DNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
KO	K03402.
Pfam	PF01316. Arg_repressor. 1 hit. PF02863. Arg_repressor_C. 1 hit. [Graphical view]
PRINTS	PR01467. ARGREPRESSOR.
ProDom	PD007402. Arg_repress. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF55252. Arg_repress. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGR2_LACPL

Accession

Primary (citable) accession number: Q8VL04
Secondary accession number(s): F9UNX9, Q7AKU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program