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Protein

Immunity-related GTPase family Q protein

Gene

Irgq

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Immunity-related GTPase family Q protein
Gene namesi
Name:Irgq
Synonyms:Irgq1
ORF Names:Fksg27
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:2667176. Irgq.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 583583Immunity-related GTPase family Q proteinPRO_0000264464Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei203 – 2031PhosphothreonineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8VIM9.
MaxQBiQ8VIM9.
PaxDbiQ8VIM9.
PeptideAtlasiQ8VIM9.
PRIDEiQ8VIM9.

PTM databases

iPTMnetiQ8VIM9.
PhosphoSiteiQ8VIM9.

Expressioni

Gene expression databases

BgeeiQ8VIM9.
CleanExiMM_IRGQ.
GenevisibleiQ8VIM9. MM.

Interactioni

Protein-protein interaction databases

IntActiQ8VIM9. 1 interaction.
MINTiMINT-4120401.

Structurei

3D structure databases

ProteinModelPortaliQ8VIM9.
SMRiQ8VIM9. Positions 8-33.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini223 – 409187IRG-type GAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili155 – 17925Sequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi409 – 574166Ala-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IH4F. Eukaryota.
ENOG41114NV. LUCA.
GeneTreeiENSGT00510000048991.
HOGENOMiHOG000060088.
HOVERGENiHBG081807.
InParanoidiQ8VIM9.
OMAiALSFLWP.
OrthoDBiEOG7N37CM.
PhylomeDBiQ8VIM9.
TreeFamiTF331897.

Family and domain databases

InterProiIPR030385. G_IRG_dom.
[Graphical view]
PROSITEiPS51716. G_IRG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VIM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLPQGDVTA LFLGPPGSGK SALIAALCGK NVDTVEIPDG RQDSGVPSLR
60 70 80 90 100
AAAPGLFLGE LSCPPAAPGP WAAEANLLVL VLPGSEGSEE PLTPALGEAA
110 120 130 140 150
RAALARGTPL LAVRNLRPGD SQNAAKARDE TAALLNSAGL GAAPLFVPPA
160 170 180 190 200
DCSSSDRCEE LERLQVVLRT QAEALQRLLP PAQDGFEVLG AAELEAVREA
210 220 230 240 250
FETGGLEAAL SWVRAGLERL GSARLDLAVA GTTNVGLVLD MLLGLDPGDP
260 270 280 290 300
GAAPASAPTG PTPYPAPERP NVVLWTVPLG PTATSPAVTP HPTHYDALIL
310 320 330 340 350
VTPGAPTEEN WAQVRSLVSP DAPLVGVRTD GQGEDPPEVL EEEKAQNASD
360 370 380 390 400
GNSGDARSEG KKAGIGDSGC TAARSPEDEL WEVLEEAPPP VFPMRPGGLP
410 420 430 440 450
GLGTWLQHAL PTAQAGALLL ALPPASPRAA RRKAAALRAG AWRPALLASL
460 470 480 490 500
AAAAAPVPGL GWACDVALLR GQLAEWRRAL GLEPAAVARR ERALGLAPGV
510 520 530 540 550
LATRTRFPGP VTRAEVEARL GSWAGEGTAG GAALSALSFL WPTGGAAATG
560 570 580
GLGYRAAHGV LLQALDEMLA DAEAVLGPPE PNQ
Length:583
Mass (Da):59,323
Last modified:March 1, 2002 - v1
Checksum:i2DDB615708C9E596
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti510 – 5101P → T in AAH56347 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF322649 mRNA. Translation: AAL33885.1.
BC056347 mRNA. Translation: AAH56347.1.
BC080294 mRNA. Translation: AAH80294.1.
CCDSiCCDS20953.1.
RefSeqiNP_694774.3. NM_153134.3.
UniGeneiMm.41108.

Genome annotation databases

EnsembliENSMUST00000049020; ENSMUSP00000036699; ENSMUSG00000041037.
GeneIDi210146.
KEGGimmu:210146.
UCSCiuc009fpv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF322649 mRNA. Translation: AAL33885.1.
BC056347 mRNA. Translation: AAH56347.1.
BC080294 mRNA. Translation: AAH80294.1.
CCDSiCCDS20953.1.
RefSeqiNP_694774.3. NM_153134.3.
UniGeneiMm.41108.

3D structure databases

ProteinModelPortaliQ8VIM9.
SMRiQ8VIM9. Positions 8-33.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8VIM9. 1 interaction.
MINTiMINT-4120401.

PTM databases

iPTMnetiQ8VIM9.
PhosphoSiteiQ8VIM9.

Proteomic databases

EPDiQ8VIM9.
MaxQBiQ8VIM9.
PaxDbiQ8VIM9.
PeptideAtlasiQ8VIM9.
PRIDEiQ8VIM9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000049020; ENSMUSP00000036699; ENSMUSG00000041037.
GeneIDi210146.
KEGGimmu:210146.
UCSCiuc009fpv.2. mouse.

Organism-specific databases

CTDi126298.
MGIiMGI:2667176. Irgq.

Phylogenomic databases

eggNOGiENOG410IH4F. Eukaryota.
ENOG41114NV. LUCA.
GeneTreeiENSGT00510000048991.
HOGENOMiHOG000060088.
HOVERGENiHBG081807.
InParanoidiQ8VIM9.
OMAiALSFLWP.
OrthoDBiEOG7N37CM.
PhylomeDBiQ8VIM9.
TreeFamiTF331897.

Miscellaneous databases

ChiTaRSiIrgq. mouse.
PROiQ8VIM9.
SOURCEiSearch...

Gene expression databases

BgeeiQ8VIM9.
CleanExiMM_IRGQ.
GenevisibleiQ8VIM9. MM.

Family and domain databases

InterProiIPR030385. G_IRG_dom.
[Graphical view]
PROSITEiPS51716. G_IRG. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of FKSG27, a novel gene related to cervical tumor."
    Wang Y.-G., Gong L.
    Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Brain.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Liver and Spleen.

Entry informationi

Entry nameiIRGQ_MOUSE
AccessioniPrimary (citable) accession number: Q8VIM9
Secondary accession number(s): Q7TNC7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: March 1, 2002
Last modified: July 6, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.