Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8VIL0

- Q8VIL0_RAT

UniProt

Q8VIL0 - Q8VIL0_RAT

Protein
Submitted name:

Retinoic acid hydroxylase

Gene

Cyp26a1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 2 (06 Dec 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. iron ion binding Source: InterPro
    3. retinoic acid 4-hydroxylase activity Source: RGD

    GO - Biological processi

    1. retinoic acid metabolic process Source: RGD

    Keywords - Molecular functioni

    MonooxygenaseUniRule annotation, Oxidoreductase

    Keywords - Ligandi

    HemeUniRule annotation, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Retinoic acid hydroxylaseImported
    Gene namesi
    Name:Cyp26a1Imported
    Synonyms:CYP26A1Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi620161. Cyp26a1.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8VIL0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8VIL0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome P450 family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG051099.
    InParanoidiQ8VIL0.
    KOiK07437.
    PhylomeDBiQ8VIL0.

    Family and domain databases

    Gene3Di1.10.630.10. 1 hit.
    InterProiIPR001128. Cyt_P450.
    IPR017972. Cyt_P450_CS.
    IPR002403. Cyt_P450_E_grp-IV.
    [Graphical view]
    PfamiPF00067. p450. 1 hit.
    [Graphical view]
    PRINTSiPR00465. EP450IV.
    PR00385. P450.
    SUPFAMiSSF48264. SSF48264. 1 hit.
    PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8VIL0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGLPALLASA LCTFVLPLLL FLAALKLWDL YCVSSRDRSC ALPLPPGTMG    50
    FPFFGETLQM VLQRRKFLQM KRRKYGFIYK THLFGRPTVR VMGADNVRRI 100
    LLGEHRLVSV HWPASVRTIL GAGCLSNLHD SSHKQRKKVI MQAFNREALQ 150
    CYVPVIAEEV SGCLEQWLSC GERGLLVYPE VKRLMFRIAM RILLGCEPGP 200
    AGGGEDEQQL VEAFEEMTRN LFSLPIDVPF SGLYRGVKAR NLIHARIEEN 250
    IRAKIRRLQA AEPDAGCKDA LQLLIEHSWE RGERLDMQAL KQSSTELLFG 300
    GHETTASAAT SLITYLGLYP HVLQKVREEI KSKGLLCKSH HEDKLDMETL 350
    EQLKYIGCVI KETLRLNPPV PGGFRVALKT FELNGYQIPK GWNVIYSICD 400
    THDVADSFTN KEEFNPDRFT SLHPEDTSRF SFIPFGGGLR SCVGKEFAKI 450
    LLKIFTVELA RRCDWQLLNG PPTMKTSPPV YPVDNLPARF THFQGDI 497
    Length:497
    Mass (Da):56,174
    Last modified:December 6, 2005 - v2
    Checksum:i242A6441F0E399EC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF439720 mRNA. Translation: AAL32056.2.
    RefSeqiNP_569092.2. NM_130408.2.
    UniGeneiRn.81072.

    Genome annotation databases

    GeneIDi154985.
    KEGGirno:154985.
    UCSCiRGD:620161. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF439720 mRNA. Translation: AAL32056.2 .
    RefSeqi NP_569092.2. NM_130408.2.
    UniGenei Rn.81072.

    3D structure databases

    ProteinModelPortali Q8VIL0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 154985.
    KEGGi rno:154985.
    UCSCi RGD:620161. rat.

    Organism-specific databases

    CTDi 1592.
    RGDi 620161. Cyp26a1.

    Phylogenomic databases

    HOVERGENi HBG051099.
    InParanoidi Q8VIL0.
    KOi K07437.
    PhylomeDBi Q8VIL0.

    Miscellaneous databases

    NextBioi 620872.

    Gene expression databases

    Genevestigatori Q8VIL0.

    Family and domain databases

    Gene3Di 1.10.630.10. 1 hit.
    InterProi IPR001128. Cyt_P450.
    IPR017972. Cyt_P450_CS.
    IPR002403. Cyt_P450_E_grp-IV.
    [Graphical view ]
    Pfami PF00067. p450. 1 hit.
    [Graphical view ]
    PRINTSi PR00465. EP450IV.
    PR00385. P450.
    SUPFAMi SSF48264. SSF48264. 1 hit.
    PROSITEi PS00086. CYTOCHROME_P450. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of rat cytochrome P450RAI (CYP26) cDNA and regulation of its gene expression by all-trans-retinoic acid in vivo."
      Wang Y., Zolfaghari R., Ross A.C.
      Arch. Biochem. Biophys. 401:235-243(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LiverImported.
    2. Zolfaghari R., Ross A.C.
      Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LiverImported.

    Entry informationi

    Entry nameiQ8VIL0_RAT
    AccessioniPrimary (citable) accession number: Q8VIL0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: December 6, 2005
    Last modified: October 1, 2014
    This is version 100 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)