Reviewed, UniProtKB/Swiss-Prot Q8VI73 (TALDO_CRIGR)

Names and origin

Protein names

Recommended name:
    Transaldolase
    EC=2.2.1.2

Gene names

Name:

TALDO1

Organism

Cricetulus griseus (Chinese hamster)

Taxonomic identifier

10029 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Cricetidae › Cricetinae › Cricetulus

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity.
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.
Subcellular location	Cytoplasm Probable. UniProtKB P37837
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
PTM	Acetylation Phosphoprotein
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transaldolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 337	337	Transaldolase		PRO_0000173563
Sites
	Active site	142	1	By similarity UniProtKB P15019
Amino acid modifications
	Modified residue	4	1	Phosphoserine By similarity
	Modified residue	219	1	N6-acetyllysine By similarity
	Modified residue	237	1	Phosphoserine By similarity
	Modified residue	269	1	N6-acetyllysine By similarity
	Modified residue	286	1	N6-acetyllysine By similarity
	Modified residue	321	1	N6-acetyllysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8VI73-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: B6AED8B21FB1C374	FASTA	337	37,386
	10 20 30 40 50 60 MSGSPVKRQR MESALDQLKQ FTTVVADTGD FNAIDEYKPQ DATTNPSLIL AAAQMPAYQE 70 80 90 100 110 120 LVEEAIAYGK KLGGPQEEQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA 130 140 150 160 170 180 RAKRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE 190 200 210 220 230 240 AGVTLISPFV GRILDWHVAN TDKKSYEPQE DPGVKSVTKI YNYYKKFGYK TIVMGASFRN 250 260 270 280 290 300 TGEIKALAGC DFLTISPKLL GELLKDNTKL APVLSIKAAQ TSDLGKIHLD EKAFRWLHSE 310 320 330 DQMAVEKLSD GIRKFAADAI KLERMLTERM FSAENGK

References

[1]	Perl A., Banki K. Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Ovary.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF128242 mRNA. Translation: AAL55523.1.
3D structure databases
HSSP	HSSP built from PDB template 1F05 based on UniProtKB P37837.
SMR	Q8VI73. Positions 13-331.
ModBase	Search...
Phylogenomic databases
HOVERGEN	Q8VI73.
Enzyme and pathway databases
BRENDA	2.2.1.2. 18.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_AB. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10683. Transaldolase. 1 hit. PTHR10683:SF3. Transaldolase_AB. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. talAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TALDO_CRIGR

Accession

Primary (citable) accession number: Q8VI73

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	March 1, 2002
Last modified:	October 13, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)