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Protein
Submitted name:

Nicotinic acetylcholine receptor alpha 2 subunit

Gene

Chrna2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. acetylcholine-activated cation-selective channel activity Source: MGI
  2. acetylcholine binding Source: Ensembl
  3. acetylcholine receptor activity Source: MGI
  4. drug binding Source: Ensembl

GO - Biological processi

  1. cation transmembrane transport Source: MGI
  2. cation transport Source: MGI
  3. protein heterooligomerization Source: Ensembl
  4. signal transduction Source: MGI
  5. synaptic transmission Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Nicotinic acetylcholine receptor alpha 2 subunitImported
Gene namesi
Name:Chrna2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:87886. Chrna2.

Subcellular locationi

GO - Cellular componenti

  1. acetylcholine-gated channel complex Source: MGI
  2. cell periphery Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ8VI12.
ExpressionAtlasiQ8VI12. baseline and differential.
GenevestigatoriQ8VI12.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022620.

Sequencei

Sequence statusi: Fragment.

Q8VI12-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NRPLPPMELH GSPGLKLSPT YHWLETNMDA EEREETEEEE EEEEDENICM
60 70 80
CAGLPDSSMG VLYGHGSLHL RAMGPEAKTP SQ
Length:82
Mass (Da):9,166
Last modified:March 1, 2002 - v1
Checksum:i466314CD40A169F8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei82 – 821Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF325345 mRNA. Translation: AAL37361.1.
UniGeneiMm.57350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF325345 mRNA. Translation: AAL37361.1.
UniGeneiMm.57350.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022620.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:87886. Chrna2.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiQ8VI12.
ExpressionAtlasiQ8VI12. baseline and differential.
GenevestigatoriQ8VI12.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Differential expression of nicotinic acetylcholine receptor subunits in fetal and neonatal mouse thymus."
    Kuo Y.-P., Lucero L., Michaels J., DeLuca D., Lukas R.L.
    J. Neuroimmunol. 130:140-154(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.

Entry informationi

Entry nameiQ8VI12_MOUSE
AccessioniPrimary (citable) accession number: Q8VI12
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: February 4, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.