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Protein

Paraneoplastic antigen Ma1 homolog

Gene

Pnma1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • inflammatory response to antigenic stimulus Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Paraneoplastic antigen Ma1 homolog
Gene namesi
Name:Pnma1
Synonyms:Ma1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi621230. Pnma1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001552011 – 353Paraneoplastic antigen Ma1 homologAdd BLAST353

Proteomic databases

PaxDbiQ8VHZ4.
PRIDEiQ8VHZ4.

Expressioni

Tissue specificityi

Testis and brain specific.1 Publication

Gene expression databases

BgeeiENSRNOG00000010553.
GenevisibleiQ8VHZ4. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014018.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi335 – 341Poly-Glu7

Sequence similaritiesi

Belongs to the PNMA family.Curated

Phylogenomic databases

eggNOGiENOG410IIH9. Eukaryota.
ENOG410YK5I. LUCA.
GeneTreeiENSGT00530000062986.
HOGENOMiHOG000013079.
HOVERGENiHBG052488.
InParanoidiQ8VHZ4.
OMAiEHTNEVM.
OrthoDBiEOG091G0BG9.
PhylomeDBiQ8VHZ4.
TreeFamiTF335054.

Family and domain databases

InterProiIPR026523. PNMA.
IPR026528. PNMA1.
[Graphical view]
PANTHERiPTHR23095. PTHR23095. 1 hit.
PTHR23095:SF17. PTHR23095:SF17. 1 hit.
PfamiPF14893. PNMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VHZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMTLLEDWC RGMDVNSQRA LLVWGIPVNC DETEIEETLQ AAMPQVSYRV
60 70 80 90 100
LGRMFWREEN AKAALLELTG TVDYSLIPRE MPGKGGLWKV VFKPPTSDAE
110 120 130 140 150
FLERLHLFLA REGWTVQDVA RVLGFQNPAP APGPEMPAEM LNYILDNVIQ
160 170 180 190 200
PLVESIWYKK LTLFSGRDIP GPGEETFDSW LEHSNEVIEE WQVSDIEKRR
210 220 230 240 250
RLMESLRGPA ADVIRILKTN NPAITTAECL KALEQVFGSV ESSRDAQVRF
260 270 280 290 300
LNTYQNPGEK LSSYVIRLEP LLQKVVDKGA IDKDNVNQAR LEQVIAGANH
310 320 330 340 350
SGALRRQLWL TGATEGPAPN LFQLLVQIRE EEAKEEEEEA EAALLQLGLE

GHF
Length:353
Mass (Da):39,793
Last modified:March 1, 2002 - v1
Checksum:iFFC3A717FDCEADA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335505 mRNA. Translation: AAL73196.1.
BC097291 mRNA. Translation: AAH97291.1.
RefSeqiNP_570833.1. NM_130820.2.
UniGeneiRn.81186.

Genome annotation databases

EnsembliENSRNOT00000014018; ENSRNOP00000014018; ENSRNOG00000010553.
GeneIDi170636.
KEGGirno:170636.
UCSCiRGD:621230. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335505 mRNA. Translation: AAL73196.1.
BC097291 mRNA. Translation: AAH97291.1.
RefSeqiNP_570833.1. NM_130820.2.
UniGeneiRn.81186.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014018.

Proteomic databases

PaxDbiQ8VHZ4.
PRIDEiQ8VHZ4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000014018; ENSRNOP00000014018; ENSRNOG00000010553.
GeneIDi170636.
KEGGirno:170636.
UCSCiRGD:621230. rat.

Organism-specific databases

CTDi9240.
RGDi621230. Pnma1.

Phylogenomic databases

eggNOGiENOG410IIH9. Eukaryota.
ENOG410YK5I. LUCA.
GeneTreeiENSGT00530000062986.
HOGENOMiHOG000013079.
HOVERGENiHBG052488.
InParanoidiQ8VHZ4.
OMAiEHTNEVM.
OrthoDBiEOG091G0BG9.
PhylomeDBiQ8VHZ4.
TreeFamiTF335054.

Miscellaneous databases

PROiQ8VHZ4.

Gene expression databases

BgeeiENSRNOG00000010553.
GenevisibleiQ8VHZ4. RN.

Family and domain databases

InterProiIPR026523. PNMA.
IPR026528. PNMA1.
[Graphical view]
PANTHERiPTHR23095. PTHR23095. 1 hit.
PTHR23095:SF17. PTHR23095:SF17. 1 hit.
PfamiPF14893. PNMA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPNMA1_RAT
AccessioniPrimary (citable) accession number: Q8VHZ4
Secondary accession number(s): Q4V8N4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: March 1, 2002
Last modified: September 7, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.