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Q8VHR8

- Q8VHR8_RAT

UniProt

Q8VHR8 - Q8VHR8_RAT

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Protein
Submitted name:

Cytokine receptor gamma chain

Gene
Il2rg
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. cytokine binding Source: RGD
  2. cytokine receptor activity Source: RGD
  3. interleukin-2 binding Source: RGD
  4. interleukin-7 binding Source: RGD

GO - Biological processi

  1. cytokine-mediated signaling pathway Source: GOC
  2. immune response Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Cytokine receptor gamma chainImported
Gene namesi
Name:Il2rgImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621466. Il2rg.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: RGD
  2. integral component of membrane Source: RGD
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ8VHR8.

Structurei

3D structure databases

ProteinModelPortaliQ8VHR8.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG052111.
PhylomeDBiQ8VHR8.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. Fibronectin_type3.
IPR003531. Hempt_rcpt_S_F1_CS.
IPR013783. Ig-like_fold.
IPR015321. IL-6_rcpt_alpha-bd.
[Graphical view]
PfamiPF00041. fn3. 1 hit.
PF09240. IL6Ra-bind. 1 hit.
[Graphical view]
SMARTiSM00060. FN3. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.
PROSITEiPS50853. FN3. 1 hit.
PS01355. HEMATOPO_REC_S_F1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8VHR8-1 [UniParc]FASTAAdd to Basket

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WSSKVLMSSG NEDTKSDLLL TSMDLKHLSV PTLPLPEVQC FVFNVEYMNC    50
TWNSSSEPQP TNLTMHYRYK GSDNNTFQEC SHYLFSKEIT SGCQIQKEDI 100
QLYQTFVVQL QDPQKPQRRA EQKLNLQNLV IPWAPENLTL YNLSESQVEL 150
RWKSRYIERC LQYLVQYRSN RDRSWTEQIV DHEPRFSLPS VDEQKLYPFR 200
VRSRFNPICG STQQWSKWSQ PIHWGSHTAE ENPSLFALEA VLIPVGTMGL 250
IITLIFVYCW LERMPXIPXI KNLEIWLL 278
Length:278
Mass (Da):32,722
Last modified:March 1, 2002 - v1
Checksum:i4011F8F774804CDD
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei278 – 2781Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF410926 mRNA. Translation: AAL61621.1.
UniGeneiRn.14508.

Genome annotation databases

UCSCiRGD:621466. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF410926 mRNA. Translation: AAL61621.1 .
UniGenei Rn.14508.

3D structure databases

ProteinModelPortali Q8VHR8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi RGD:621466. rat.

Organism-specific databases

RGDi 621466. Il2rg.

Phylogenomic databases

HOVERGENi HBG052111.
PhylomeDBi Q8VHR8.

Gene expression databases

Genevestigatori Q8VHR8.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
InterProi IPR003961. Fibronectin_type3.
IPR003531. Hempt_rcpt_S_F1_CS.
IPR013783. Ig-like_fold.
IPR015321. IL-6_rcpt_alpha-bd.
[Graphical view ]
Pfami PF00041. fn3. 1 hit.
PF09240. IL6Ra-bind. 1 hit.
[Graphical view ]
SMARTi SM00060. FN3. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 2 hits.
PROSITEi PS50853. FN3. 1 hit.
PS01355. HEMATOPO_REC_S_F1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain."
    Olosz F., Malek T.R.
    J. Biol. Chem. 277:12047-12052(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.

Entry informationi

Entry nameiQ8VHR8_RAT
AccessioniPrimary (citable) accession number: Q8VHR8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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