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Q8VHR8

- Q8VHR8_RAT

UniProt

Q8VHR8 - Q8VHR8_RAT

Protein
Submitted name:

Cytokine receptor gamma chain

Gene

Il2rg

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. cytokine binding Source: RGD
    2. cytokine receptor activity Source: RGD
    3. interleukin-2 binding Source: RGD
    4. interleukin-7 binding Source: RGD

    GO - Biological processi

    1. cytokine-mediated signaling pathway Source: GOC
    2. immune response Source: RGD

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cytokine receptor gamma chainImported
    Gene namesi
    Name:Il2rgImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi621466. Il2rg.

    Subcellular locationi

    GO - Cellular componenti

    1. cell surface Source: RGD
    2. integral component of membrane Source: RGD

    Expressioni

    Gene expression databases

    GenevestigatoriQ8VHR8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8VHR8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG052111.
    PhylomeDBiQ8VHR8.

    Family and domain databases

    Gene3Di2.60.40.10. 2 hits.
    InterProiIPR003961. Fibronectin_type3.
    IPR003531. Hempt_rcpt_S_F1_CS.
    IPR013783. Ig-like_fold.
    IPR015321. IL-6_rcpt_alpha-bd.
    [Graphical view]
    PfamiPF00041. fn3. 1 hit.
    PF09240. IL6Ra-bind. 1 hit.
    [Graphical view]
    SMARTiSM00060. FN3. 1 hit.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 2 hits.
    PROSITEiPS50853. FN3. 1 hit.
    PS01355. HEMATOPO_REC_S_F1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8VHR8-1 [UniParc]FASTAAdd to Basket

    « Hide

    WSSKVLMSSG NEDTKSDLLL TSMDLKHLSV PTLPLPEVQC FVFNVEYMNC    50
    TWNSSSEPQP TNLTMHYRYK GSDNNTFQEC SHYLFSKEIT SGCQIQKEDI 100
    QLYQTFVVQL QDPQKPQRRA EQKLNLQNLV IPWAPENLTL YNLSESQVEL 150
    RWKSRYIERC LQYLVQYRSN RDRSWTEQIV DHEPRFSLPS VDEQKLYPFR 200
    VRSRFNPICG STQQWSKWSQ PIHWGSHTAE ENPSLFALEA VLIPVGTMGL 250
    IITLIFVYCW LERMPXIPXI KNLEIWLL 278
    Length:278
    Mass (Da):32,722
    Last modified:March 1, 2002 - v1
    Checksum:i4011F8F774804CDD
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei278 – 2781Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF410926 mRNA. Translation: AAL61621.1.
    UniGeneiRn.14508.

    Genome annotation databases

    UCSCiRGD:621466. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF410926 mRNA. Translation: AAL61621.1 .
    UniGenei Rn.14508.

    3D structure databases

    ProteinModelPortali Q8VHR8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi RGD:621466. rat.

    Organism-specific databases

    RGDi 621466. Il2rg.

    Phylogenomic databases

    HOVERGENi HBG052111.
    PhylomeDBi Q8VHR8.

    Gene expression databases

    Genevestigatori Q8VHR8.

    Family and domain databases

    Gene3Di 2.60.40.10. 2 hits.
    InterProi IPR003961. Fibronectin_type3.
    IPR003531. Hempt_rcpt_S_F1_CS.
    IPR013783. Ig-like_fold.
    IPR015321. IL-6_rcpt_alpha-bd.
    [Graphical view ]
    Pfami PF00041. fn3. 1 hit.
    PF09240. IL6Ra-bind. 1 hit.
    [Graphical view ]
    SMARTi SM00060. FN3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 2 hits.
    PROSITEi PS50853. FN3. 1 hit.
    PS01355. HEMATOPO_REC_S_F1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain."
      Olosz F., Malek T.R.
      J. Biol. Chem. 277:12047-12052(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Sprague-DawleyImported.

    Entry informationi

    Entry nameiQ8VHR8_RAT
    AccessioniPrimary (citable) accession number: Q8VHR8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)