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Q8VHP0

- Q8VHP0_MOUSE

UniProt

Q8VHP0 - Q8VHP0_MOUSE

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Protein
Submitted name:

Pax2 protein

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. core promoter proximal region sequence-specific DNA binding Source: Ensembl

GO - Biological processi

  1. aging Source: Ensembl
  2. cellular response to epidermal growth factor stimulus Source: Ensembl
  3. metanephric epithelium development Source: Ensembl
  4. negative regulation of apoptotic process Source: Ensembl
  5. negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Ensembl
  6. negative regulation of cytolysis Source: Ensembl
  7. negative regulation of reactive oxygen species metabolic process Source: Ensembl
  8. negative regulation of transcription, DNA-templated Source: Ensembl
  9. positive regulation of epithelial cell proliferation Source: Ensembl
  10. positive regulation of transcription, DNA-templated Source: Ensembl
  11. regulation of metanephros size Source: Ensembl
  12. response to nutrient levels Source: Ensembl
  13. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Pax2 proteinImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

  1. centriolar satellite Source: Ensembl
  2. lysosome Source: Ensembl
  3. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiQ8VHP0.
ExpressionAtlasiQ8VHP0. baseline.
GenevestigatoriQ8VHP0.

Structurei

3D structure databases

ProteinModelPortaliQ8VHP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 paired domain.UniRule annotation
Contains paired domain.SAAS annotation

Keywords - Domaini

Paired boxUniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00292. PAX. 1 hit.
[Graphical view]
PRINTSiPR00027. PAIREDBOX.
SMARTiSM00351. PAX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8VHP0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDMHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP
60
CDISRQLRVS HGCVSKILG
Length:69
Mass (Da):7,585
Last modified:March 1, 2002 - v1
Checksum:i24D8CE301C771E41
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei69 – 691Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF433638 Genomic DNA. Translation: AAL69891.1.
UniGeneiMm.192158.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF433638 Genomic DNA. Translation: AAL69891.1 .
UniGenei Mm.192158.

3D structure databases

ProteinModelPortali Q8VHP0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

Bgeei Q8VHP0.
ExpressionAtlasi Q8VHP0. baseline.
Genevestigatori Q8VHP0.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00292. PAX. 1 hit.
[Graphical view ]
PRINTSi PR00027. PAIREDBOX.
SMARTi SM00351. PAX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers."
    Pfeffer P.L., Payer B., Reim G., di Magliano M.P., Busslinger M.
    Development 129:307-318(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8VHP0_MOUSE
AccessioniPrimary (citable) accession number: Q8VHP0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)