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Q8VHK4

- Q8VHK4_MOUSE

UniProt

Q8VHK4 - Q8VHK4_MOUSE

Protein
Submitted name:

Aggrecanase-1

Gene

Adamts4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: MGI
    2. metallopeptidase activity Source: MGI
    3. protein binding Source: MGI

    GO - Biological processi

    1. defense response to bacterium Source: MGI
    2. proteolysis Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Aggrecanase-1Imported
    Gene namesi
    Name:Adamts4Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1339949. Adamts4.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ8VHK4.
    BgeeiQ8VHK4.
    GenevestigatoriQ8VHK4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8VHK4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains peptidase M12B domain.SAAS annotation

    Phylogenomic databases

    InParanoidiQ8VHK4.

    Family and domain databases

    Gene3Di3.40.390.10. 1 hit.
    InterProiIPR024079. MetalloPept_cat_dom.
    IPR001590. Peptidase_M12B.
    [Graphical view]
    PROSITEiPS50215. ADAM_MEPRO. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8VHK4-1 [UniParc]FASTAAdd to Basket

    « Hide

    HVFNMLHDNS KPCTNLNGQG GSSRHVMAPV MAHVDPEEPW SPCSARFITD    50
    FLDNGYGHCL LDKPEAPLHL PATFPGKDYD ADRQCQLTFG PDSSHCPQLP 100
    PPCAALWCSG HLNGHAM 117
    Length:117
    Mass (Da):12,775
    Last modified:March 1, 2002 - v1
    Checksum:i941853E69F4526C3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei117 – 1171Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF449483 mRNA. Translation: AAL68774.1.
    UniGeneiMm.491147.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF449483 mRNA. Translation: AAL68774.1 .
    UniGenei Mm.491147.

    3D structure databases

    ProteinModelPortali Q8VHK4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1339949. Adamts4.

    Phylogenomic databases

    InParanoidi Q8VHK4.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8VHK4.
    Bgeei Q8VHK4.
    Genevestigatori Q8VHK4.

    Family and domain databases

    Gene3Di 3.40.390.10. 1 hit.
    InterProi IPR024079. MetalloPept_cat_dom.
    IPR001590. Peptidase_M12B.
    [Graphical view ]
    PROSITEi PS50215. ADAM_MEPRO. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of murine aggrecanases."
      Daikou S., Glaeser K.E., Horner A., Davies E.M., Jeffcott L.B.
      Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ8VHK4_MOUSE
    AccessioniPrimary (citable) accession number: Q8VHK4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)