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Q8VHK4

- Q8VHK4_MOUSE

UniProt

Q8VHK4 - Q8VHK4_MOUSE

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Protein
Submitted name:

Aggrecanase-1

Gene
Adamts4
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metalloendopeptidase activity Source: MGI
  2. metallopeptidase activity Source: MGI
  3. protein binding Source: MGI

GO - Biological processi

  1. defense response to bacterium Source: MGI
  2. proteolysis Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, MetalloproteaseSAAS annotations, Protease

Names & Taxonomyi

Protein namesi
Submitted name:
Aggrecanase-1Imported
Gene namesi
Name:Adamts4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1339949. Adamts4.

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ8VHK4.
BgeeiQ8VHK4.
GenevestigatoriQ8VHK4.

Structurei

3D structure databases

ProteinModelPortaliQ8VHK4.

Family & Domainsi

Sequence similaritiesi

Contains peptidase M12B domain.SAAS annotations

Phylogenomic databases

InParanoidiQ8VHK4.

Family and domain databases

Gene3Di3.40.390.10. 1 hit.
InterProiIPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
[Graphical view]
PROSITEiPS50215. ADAM_MEPRO. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8VHK4-1 [UniParc]FASTAAdd to Basket

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HVFNMLHDNS KPCTNLNGQG GSSRHVMAPV MAHVDPEEPW SPCSARFITD    50
FLDNGYGHCL LDKPEAPLHL PATFPGKDYD ADRQCQLTFG PDSSHCPQLP 100
PPCAALWCSG HLNGHAM 117
Length:117
Mass (Da):12,775
Last modified:March 1, 2002 - v1
Checksum:i941853E69F4526C3
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei117 – 1171Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF449483 mRNA. Translation: AAL68774.1.
UniGeneiMm.491147.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF449483 mRNA. Translation: AAL68774.1 .
UniGenei Mm.491147.

3D structure databases

ProteinModelPortali Q8VHK4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1339949. Adamts4.

Phylogenomic databases

InParanoidi Q8VHK4.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q8VHK4.
Bgeei Q8VHK4.
Genevestigatori Q8VHK4.

Family and domain databases

Gene3Di 3.40.390.10. 1 hit.
InterProi IPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
[Graphical view ]
PROSITEi PS50215. ADAM_MEPRO. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Expression of murine aggrecanases."
    Daikou S., Glaeser K.E., Horner A., Davies E.M., Jeffcott L.B.
    Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8VHK4_MOUSE
AccessioniPrimary (citable) accession number: Q8VHK4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: June 11, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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