ID   Q8VHE2_MOUSE            Unreviewed;       176 AA.
AC   Q8VHE2;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 113.
DE   SubName: Full=LATS2B {ECO:0000313|EMBL:AAK07725.1};
DE   SubName: Full=Large tumor suppressor 2 {ECO:0000313|Ensembl:ENSMUSP00000077130.7};
GN   Name=Lats2 {ECO:0000313|EMBL:AAK07725.1,
GN   ECO:0000313|Ensembl:ENSMUSP00000077130.7,
GN   ECO:0000313|MGI:MGI:1354386};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAK07725.1};
RN   [1] {ECO:0000313|EMBL:AAK07725.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BALB/c {ECO:0000313|EMBL:AAK07725.1};
RC   TISSUE=Bone marrow {ECO:0000313|EMBL:AAK07725.1};
RA   Chen Y.-G., Mantalaris A., Wu J.H.D.;
RT   "Identification and Tissue Distribution of Two Novel Spliced Variants of
RT   the Mouse Lats2 Gene.";
RL   Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000077130.7, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000077130.7,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000077130.7}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000077130.7};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AY015061; AAK07725.1; -; mRNA.
DR   RefSeq; NP_700431.1; NM_153382.1.
DR   RefSeq; XP_006519288.1; XM_006519225.2.
DR   ProteomicsDB; 332444; -.
DR   DNASU; 50523; -.
DR   Ensembl; ENSMUST00000077981.7; ENSMUSP00000077130.7; ENSMUSG00000021959.17.
DR   GeneID; 50523; -.
DR   UCSC; uc007udm.1; mouse.
DR   AGR; MGI:1354386; -.
DR   CTD; 26524; -.
DR   MGI; MGI:1354386; Lats2.
DR   VEuPathDB; HostDB:ENSMUSG00000021959; -.
DR   GeneTree; ENSGT00940000159161; -.
DR   OrthoDB; 5266359at2759; -.
DR   BioGRID-ORCS; 50523; 2 hits in 82 CRISPR screens.
DR   ChiTaRS; Lats2; mouse.
DR   Proteomes; UP000000589; Chromosome 14.
DR   Bgee; ENSMUSG00000021959; Expressed in ascending aorta and 255 other cell types or tissues.
PE   2: Evidence at transcript level;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   REGION          23..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        27..42
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   176 AA;  19203 MW;  B4B80DBE0ADC756E CRC64;
     MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KASTQGLLVG PNSDTSLDAK VLGSKDASRQ
     QQMRATPKFG PYQKALREIR YSLLPFANES GTSAAAEVNR QMLQELVNAG CDQMHIPGAC
     LFLEMLLSVP PISQTAAPGL QAHRLLQLCS VCEFKLGPSH LYLKHGASRL LSPLCP
//