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Q8VHE2

- Q8VHE2_MOUSE

UniProt

Q8VHE2 - Q8VHE2_MOUSE

Protein
Submitted name:

LATS2B

Gene

Lats2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. protein serine/threonine kinase activity Source: InterPro

    GO - Biological processi

    1. cellular protein localization Source: MGI
    2. hippo signaling Source: MGI
    3. keratinocyte differentiation Source: MGI
    4. mitotic nuclear division Source: InterPro
    5. negative regulation of canonical Wnt signaling pathway Source: MGI
    6. protein phosphorylation Source: MGI
    7. regulation of organ growth Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    LATS2BImported
    Submitted name:
    Serine/threonine-protein kinase LATS2Imported
    Gene namesi
    Name:Lats2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:1354386. Lats2.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8VHE2.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00750000117422.
    HOGENOMiHOG000150627.
    HOVERGENiHBG073574.
    KOiK08791.

    Family and domain databases

    InterProiIPR028742. LATS2.
    [Graphical view]
    PANTHERiPTHR24356:SF149. PTHR24356:SF149. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8VHE2-1 [UniParc]FASTAAdd to Basket

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    MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KASTQGLLVG PNSDTSLDAK    50
    VLGSKDASRQ QQMRATPKFG PYQKALREIR YSLLPFANES GTSAAAEVNR 100
    QMLQELVNAG CDQMHIPGAC LFLEMLLSVP PISQTAAPGL QAHRLLQLCS 150
    VCEFKLGPSH LYLKHGASRL LSPLCP 176
    Length:176
    Mass (Da):19,203
    Last modified:March 1, 2002 - v1
    Checksum:iB4B80DBE0ADC756E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC154504 Genomic DNA. No translation available.
    AY015061 mRNA. Translation: AAK07725.1.
    RefSeqiNP_700431.1. NM_153382.1.
    XP_006519288.1. XM_006519225.1.
    UniGeneiMm.347899.

    Genome annotation databases

    EnsembliENSMUST00000077981; ENSMUSP00000077130; ENSMUSG00000021959.
    GeneIDi50523.
    KEGGimmu:50523.
    UCSCiuc007udm.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC154504 Genomic DNA. No translation available.
    AY015061 mRNA. Translation: AAK07725.1 .
    RefSeqi NP_700431.1. NM_153382.1.
    XP_006519288.1. XM_006519225.1.
    UniGenei Mm.347899.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000077981 ; ENSMUSP00000077130 ; ENSMUSG00000021959 .
    GeneIDi 50523.
    KEGGi mmu:50523.
    UCSCi uc007udm.1. mouse.

    Organism-specific databases

    CTDi 26524.
    MGIi MGI:1354386. Lats2.

    Phylogenomic databases

    GeneTreei ENSGT00750000117422.
    HOGENOMi HOG000150627.
    HOVERGENi HBG073574.
    KOi K08791.

    Miscellaneous databases

    ChiTaRSi LATS2. mouse.
    NextBioi 307518.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8VHE2.

    Family and domain databases

    InterProi IPR028742. LATS2.
    [Graphical view ]
    PANTHERi PTHR24356:SF149. PTHR24356:SF149. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Identification and Tissue Distribution of Two Novel Spliced Variants of the Mouse Lats2 Gene."
      Chen Y.-G., Mantalaris A., Wu J.H.D.
      Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/cImported.
      Tissue: Bone marrowImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8VHE2_MOUSE
    AccessioniPrimary (citable) accession number: Q8VHE2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3