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Protein
Submitted name:

LATS2B

Gene

Lats2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular protein localization Source: MGI
  • G1/S transition of mitotic cell cycle Source: MGI
  • hippo signaling Source: MGI
  • hormone-mediated signaling pathway Source: MGI
  • intracellular signal transduction Source: MGI
  • keratinocyte differentiation Source: MGI
  • mitotic nuclear division Source: InterPro
  • negative regulation of canonical Wnt signaling pathway Source: MGI
  • negative regulation of cyclin-dependent protein serine/threonine kinase activity Source: MGI
  • protein phosphorylation Source: MGI
  • regulation of organ growth Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
LATS2BImported
Submitted name:
Serine/threonine-protein kinase LATS2Imported
Gene namesi
Name:Lats2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1354386. Lats2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ8VHE2. baseline and differential.
GenevestigatoriQ8VHE2.

Structurei

3D structure databases

ProteinModelPortaliQ8VHE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118994.
HOGENOMiHOG000150627.
HOVERGENiHBG073574.
KOiK08791.

Family and domain databases

InterProiIPR028742. LATS2.
[Graphical view]
PANTHERiPTHR24356:SF149. PTHR24356:SF149. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VHE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KASTQGLLVG PNSDTSLDAK
60 70 80 90 100
VLGSKDASRQ QQMRATPKFG PYQKALREIR YSLLPFANES GTSAAAEVNR
110 120 130 140 150
QMLQELVNAG CDQMHIPGAC LFLEMLLSVP PISQTAAPGL QAHRLLQLCS
160 170
VCEFKLGPSH LYLKHGASRL LSPLCP
Length:176
Mass (Da):19,203
Last modified:March 1, 2002 - v1
Checksum:iB4B80DBE0ADC756E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154504 Genomic DNA. No translation available.
AY015061 mRNA. Translation: AAK07725.1.
RefSeqiNP_700431.1. NM_153382.1.
XP_006519288.1. XM_006519225.2.
UniGeneiMm.347899.

Genome annotation databases

EnsembliENSMUST00000077981; ENSMUSP00000077130; ENSMUSG00000021959.
GeneIDi50523.
KEGGimmu:50523.
UCSCiuc007udm.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154504 Genomic DNA. No translation available.
AY015061 mRNA. Translation: AAK07725.1.
RefSeqiNP_700431.1. NM_153382.1.
XP_006519288.1. XM_006519225.2.
UniGeneiMm.347899.

3D structure databases

ProteinModelPortaliQ8VHE2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000077981; ENSMUSP00000077130; ENSMUSG00000021959.
GeneIDi50523.
KEGGimmu:50523.
UCSCiuc007udm.1. mouse.

Organism-specific databases

CTDi26524.
MGIiMGI:1354386. Lats2.

Phylogenomic databases

GeneTreeiENSGT00760000118994.
HOGENOMiHOG000150627.
HOVERGENiHBG073574.
KOiK08791.

Miscellaneous databases

ChiTaRSiLats2. mouse.
NextBioi307518.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiQ8VHE2. baseline and differential.
GenevestigatoriQ8VHE2.

Family and domain databases

InterProiIPR028742. LATS2.
[Graphical view]
PANTHERiPTHR24356:SF149. PTHR24356:SF149. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and Tissue Distribution of Two Novel Spliced Variants of the Mouse Lats2 Gene."
    Chen Y.-G., Mantalaris A., Wu J.H.D.
    Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: Bone marrowImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8VHE2_MOUSE
AccessioniPrimary (citable) accession number: Q8VHE2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: May 27, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.