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Q8VHE2

- Q8VHE2_MOUSE

UniProt

Q8VHE2 - Q8VHE2_MOUSE

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Protein
Submitted name:

LATS2B

Gene

Lats2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein serine/threonine kinase activity Source: InterPro

GO - Biological processi

  1. cellular protein localization Source: MGI
  2. hippo signaling Source: MGI
  3. keratinocyte differentiation Source: MGI
  4. mitotic nuclear division Source: InterPro
  5. negative regulation of canonical Wnt signaling pathway Source: MGI
  6. protein phosphorylation Source: MGI
  7. regulation of organ growth Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
LATS2BImported
Submitted name:
Serine/threonine-protein kinase LATS2Imported
Gene namesi
Name:Lats2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:1354386. Lats2.

Expressioni

Gene expression databases

GenevestigatoriQ8VHE2.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118994.
HOGENOMiHOG000150627.
HOVERGENiHBG073574.
KOiK08791.

Family and domain databases

InterProiIPR028742. LATS2.
[Graphical view]
PANTHERiPTHR24356:SF149. PTHR24356:SF149. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VHE2-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KASTQGLLVG PNSDTSLDAK
60 70 80 90 100
VLGSKDASRQ QQMRATPKFG PYQKALREIR YSLLPFANES GTSAAAEVNR
110 120 130 140 150
QMLQELVNAG CDQMHIPGAC LFLEMLLSVP PISQTAAPGL QAHRLLQLCS
160 170
VCEFKLGPSH LYLKHGASRL LSPLCP
Length:176
Mass (Da):19,203
Last modified:March 1, 2002 - v1
Checksum:iB4B80DBE0ADC756E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154504 Genomic DNA. No translation available.
AY015061 mRNA. Translation: AAK07725.1.
RefSeqiNP_700431.1. NM_153382.1.
XP_006519288.1. XM_006519225.1.
UniGeneiMm.347899.

Genome annotation databases

EnsembliENSMUST00000077981; ENSMUSP00000077130; ENSMUSG00000021959.
GeneIDi50523.
KEGGimmu:50523.
UCSCiuc007udm.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154504 Genomic DNA. No translation available.
AY015061 mRNA. Translation: AAK07725.1 .
RefSeqi NP_700431.1. NM_153382.1.
XP_006519288.1. XM_006519225.1.
UniGenei Mm.347899.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000077981 ; ENSMUSP00000077130 ; ENSMUSG00000021959 .
GeneIDi 50523.
KEGGi mmu:50523.
UCSCi uc007udm.1. mouse.

Organism-specific databases

CTDi 26524.
MGIi MGI:1354386. Lats2.

Phylogenomic databases

GeneTreei ENSGT00760000118994.
HOGENOMi HOG000150627.
HOVERGENi HBG073574.
KOi K08791.

Miscellaneous databases

ChiTaRSi LATS2. mouse.
NextBioi 307518.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8VHE2.

Family and domain databases

InterProi IPR028742. LATS2.
[Graphical view ]
PANTHERi PTHR24356:SF149. PTHR24356:SF149. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and Tissue Distribution of Two Novel Spliced Variants of the Mouse Lats2 Gene."
    Chen Y.-G., Mantalaris A., Wu J.H.D.
    Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: Bone marrowImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8VHE2_MOUSE
AccessioniPrimary (citable) accession number: Q8VHE2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3